2019
Pharmacological interventions for the treatment of delirium in critically ill adults
Burry L, Hutton B, Williamson DR, Mehta S, Adhikari NK, Cheng W, Ely EW, Egerod I, Fergusson DA, Rose L. Pharmacological interventions for the treatment of delirium in critically ill adults. 2019, 9: cd011749. PMID: 31479532, PMCID: PMC6719921, DOI: 10.1002/14651858.cd011749.pub2.Peer-Reviewed Original ResearchConceptsTreatment of deliriumIntensive care unitComa-free daysDuration of deliriumNon-pharmacological interventionsLong-term outcomesIll adultsPharmacological interventionsMechanical ventilationAgonist dexmedetomidineDrug classesICU stayIll patientsReview authorsPatient outcomesOvid MEDLINELonger intensive care unitLong-term cognitive outcomesActive drug treatmentAvailable pharmacological interventionsMultiple pharmacological interventionsLonger ICU stayIll adult patientsResolution of symptomsHigh dependency unit
2018
Prognostic Accuracy of the Quick Sequential Organ Failure Assessment for Mortality in Patients With Suspected Infection: A Systematic Review and Meta-analysis.
Fernando SM, Tran A, Taljaard M, Cheng W, Rochwerg B, Seely AJE, Perry JJ. Prognostic Accuracy of the Quick Sequential Organ Failure Assessment for Mortality in Patients With Suspected Infection: A Systematic Review and Meta-analysis. Annals Of Internal Medicine 2018, 168: 266-275. PMID: 29404582, DOI: 10.7326/m17-2820.Peer-Reviewed Original ResearchConceptsQuick Sequential Organ Failure AssessmentPrediction of mortalitySequential Organ Failure AssessmentOrgan Failure AssessmentIntensive care unitNon-ICU populationSIRS criteriaICU populationAdult patientsPooled specificityEmergency departmentPooled sensitivityPrognostic accuracySystemic inflammatory response syndrome criteriaShort-term mortalityScreening of patientsFailure AssessmentEnglish-language studiesSyndrome criteriaTreatment initiationCare unitPatient selectionStudy qualityEmergency physiciansHospital wards