2015
Neonatal Sepsis 2004-2013: The Rise and Fall of Coagulase-Negative Staphylococci
Bizzarro MJ, Shabanova V, Baltimore RS, Dembry LM, Ehrenkranz RA, Gallagher PG. Neonatal Sepsis 2004-2013: The Rise and Fall of Coagulase-Negative Staphylococci. The Journal Of Pediatrics 2015, 166: 1193-1199. PMID: 25919728, PMCID: PMC4413005, DOI: 10.1016/j.jpeds.2015.02.009.Peer-Reviewed Original ResearchConceptsEarly-onset sepsisLate-onset sepsisNeonatal intensive care unitCoagulase-negative staphylococciIntensive care unitCare unitLevel IV neonatal intensive care unitEpisodes of sepsisLow birth weightInfection prevention initiativesInfection prevention effortsPercent of casesGroup B streptococciHospital courseSepsis episodesMost infantsBirth weightCommon organismB streptococciSepsisOutcome dataAdditional surveillancePrevention effortsStudy periodInfants
2013
Neutrophil CD64 with Hematologic Criteria for Diagnosis of Neonatal Sepsis
Streimish I, Bizzarro M, Northrup V, Wang C, Renna S, Koval N, Li FY, Ehrenkranz RA, Rinder HM, Bhandari V. Neutrophil CD64 with Hematologic Criteria for Diagnosis of Neonatal Sepsis. American Journal Of Perinatology 2013, 31: 021-030. PMID: 23456906, DOI: 10.1055/s-0033-1334453.Peer-Reviewed Original ResearchConceptsCulture-proven sepsisClinical sepsisNeutrophil CD64CD64 indexNeonatal sepsisHematologic criteriaSingle-centre neonatal intensive care unitEarly-onset clinical sepsisNeonatal intensive care unitNeutrophil CD64 indexProspective observational cohortAbsolute neutrophil countNormal birth weightIntensive care unitAbsolute band countNegative predictive valueAdditional markersSepsis evaluationNeutrophil countObservational cohortCare unitBirth weightHematologic parametersSepsisCD64
2012
Neutrophil CD64 as a Diagnostic Marker in Neonatal Sepsis
Streimish I, Bizzarro M, Northrup V, Wang C, Renna S, Koval N, Li FY, Ehrenkranz R, Rinder HM, Bhandari V. Neutrophil CD64 as a Diagnostic Marker in Neonatal Sepsis. The Pediatric Infectious Disease Journal 2012, 31: 777-781. PMID: 22481422, PMCID: PMC3375383, DOI: 10.1097/inf.0b013e318256fb07.Peer-Reviewed Original Research
2011
Antibiotic Exposure in the Newborn Intensive Care Unit and the Risk of Necrotizing Enterocolitis
Alexander VN, Northrup V, Bizzarro MJ. Antibiotic Exposure in the Newborn Intensive Care Unit and the Risk of Necrotizing Enterocolitis. The Journal Of Pediatrics 2011, 159: 392-397. PMID: 21489560, PMCID: PMC3137655, DOI: 10.1016/j.jpeds.2011.02.035.Peer-Reviewed Original ResearchConceptsRisk of NECAntibiotic exposureControl subjectsRisk factorsNewborn intensive care unitCulture-proven sepsisFull enteral feedingCases of NECIndependent risk factorDiagnosis of NECRespiratory distress syndromeIntensive care unitRisk factor dataPrior sepsisEnteral feedingNecrotizing enterocolitisDistress syndromeCare unitGestational ageBirth weightAntibiotic useCase subjectsSepsisMultivariate analysisNeonates
2010
A Quality Improvement Initiative to Reduce Central Line–Associated Bloodstream Infections in a Neonatal Intensive Care Unit
Bizzarro MJ, Sabo B, Noonan M, Bonfiglio MP, Northrup V, Diefenbach K. A Quality Improvement Initiative to Reduce Central Line–Associated Bloodstream Infections in a Neonatal Intensive Care Unit. Infection Control And Hospital Epidemiology 2010, 31: 241-248. PMID: 20102278, DOI: 10.1086/650448.Peer-Reviewed Original ResearchConceptsCentral line-associated bloodstream infectionsNeonatal intensive care unitLate-onset sepsisRate of CLABSINational Healthcare Safety NetworkCentral venous cathetersIntensive care unitCLABSI ratesBloodstream infectionsCare unitLevel III neonatal intensive care unitCentral Line–Associated Bloodstream InfectionsLine-associated bloodstream infectionsLine–Associated Bloodstream InfectionsEvidence-based guidelinesQuality improvement initiativesQuality improvement committeeCVC placementVenous cathetersNICU patientsInpatient careClinical practicePreintervention dataQuasi-experimental studySepsis