Knowledge gaps in the epidemiology of severe dengue impede vaccine evaluation
Sharp T, Anderson K, Katzelnick L, Clapham H, Johansson M, Morrison A, Harris E, Paz-Bailey G, Waterman S. Knowledge gaps in the epidemiology of severe dengue impede vaccine evaluation. The Lancet Infectious Diseases 2021, 22: e42-e51. PMID: 34265259, PMCID: PMC11379041, DOI: 10.1016/s1473-3099(20)30871-9.Peer-Reviewed Original ResearchConceptsDengue virus infectionSevere dengueVirus infectionDisease severityAnti-dengue virus antibodiesMajor organ failureHospital admissionOrgan failureVaccine evaluationClinical spectrumVaccine trialsPrevious infectionRisk factorsVirus antibodiesClinical studiesClinical practiceDengue virusStudy participantsInfectionLack of specificityHost factorsVirus characteristicsDengueEpidemiologyRange of agesDengue Virus Infections among Peace Corps Volunteers in Timor-Leste, 2018–2019
Sánchez-González L, Venuto M, Poe S, Major C, Baskara L, Abdiyeva S, Murphy D, Munoz-Jordan J, Medina F, Paz-Bailey G, Petersen K, Becker K, Sharp T. Dengue Virus Infections among Peace Corps Volunteers in Timor-Leste, 2018–2019. American Journal Of Tropical Medicine And Hygiene 2021, 104: 2202-2209. PMID: 33901000, PMCID: PMC8176509, DOI: 10.4269/ajtmh.21-0020.Peer-Reviewed Original ResearchConceptsDengue virus infectionMosquito avoidance behaviorsVirus infectionPeace Corps volunteersAnti-DENV IgM antibodiesPeace Corps Medical OfficersOngoing health risksReporting feverDENV infectionIgM antibodiesRecent infectionEpidemiological characteristicsClinical managementMedical recordsMosquito bitesBed netsCollected bloodHealth servicesTravel historyDisease severityDisease controlInfectionMedical officersPreventive measuresDengue