2015
Estrogen- and Satiety State-Dependent Metabolic Lateralization in the Hypothalamus of Female Rats
Toth I, Kiss DS, Jocsak G, Somogyi V, Toronyi E, Bartha T, Frenyo LV, Horvath TL, Zsarnovszky A. Estrogen- and Satiety State-Dependent Metabolic Lateralization in the Hypothalamus of Female Rats. PLOS ONE 2015, 10: e0137462. PMID: 26339901, PMCID: PMC4560379, DOI: 10.1371/journal.pone.0137462.Peer-Reviewed Original ResearchConceptsAd libitum fed animalsFemale ratsRight-sided dominanceSatiety stateFed animalsOvariectomized female ratsContribution of estrogenMetabolic differencesHours of fastingIntensity of cellsState 3 mitochondrial respirationHypothalamic functionMetabolic asymmetryTissue metabolismHypothalamusEstrogenProportion of animalsHypothalamic asymmetryRatsAd libitumLateralizationHigher centersMitochondrial respiration rateEnergy metabolism
2009
The role of mitochondrial uncoupling proteins in lifespan
Dietrich MO, Horvath TL. The role of mitochondrial uncoupling proteins in lifespan. Pflügers Archiv - European Journal Of Physiology 2009, 459: 269-275. PMID: 19760284, PMCID: PMC2809791, DOI: 10.1007/s00424-009-0729-0.Peer-Reviewed Original ResearchConceptsMitochondrial inner membraneCellular biochemical reactionsMitochondrial uncoupling proteinProduction of ATPCellular functionsInner membraneSpecialized proteinsBreakdown of lipidsMain organellesExcess of ROSPhysiological uncouplingOxidative phosphorylationUncoupling proteinAdenosine triphosphateOxygen reactive speciesROS productionProteinEnergetic substratesBiochemical reactionsCellular damageMitochondriaROSIntermediate substrateUCPShed light