2023
The potential of saliva as an accessible and sensitive sample type for the detection of respiratory pathogens and host immunity
Laxton C, Peno C, Hahn A, Allicock O, Perniciaro S, Wyllie A. The potential of saliva as an accessible and sensitive sample type for the detection of respiratory pathogens and host immunity. The Lancet Microbe 2023, 4: e837-e850. PMID: 37516121, DOI: 10.1016/s2666-5247(23)00135-0.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsSARS-CoV-2Respiratory pathogensPotential of salivaUsefulness of salivaUse of salivaRespiratory specimenRespiratory secretionsDisease burdenImmunological componentsImmunity surveillanceClinical utilityHost immunityClinical useDiagnostic testsNon-invasive natureSalivaCOVID-19 pandemicSample typesMethodological factorsPathogensImmunitySecretion
2022
Reemergence of Invasive Pneumococcal Disease in Germany During the Spring and Summer of 2021
Perniciaro S, van der Linden M, Weinberger DM. Reemergence of Invasive Pneumococcal Disease in Germany During the Spring and Summer of 2021. Clinical Infectious Diseases 2022, 75: 1149-1153. PMID: 35136983, PMCID: PMC9383454, DOI: 10.1093/cid/ciac100.Peer-Reviewed Original ResearchConceptsInvasive pneumococcal diseaseIPD surveillance dataIPD casesIPD incidencePneumococcal diseaseNonpharmaceutical interventionsVaccine-serotype invasive pneumococcal diseaseSurveillance dataCoronavirus disease 2019 (COVID-19) pandemicSARS-CoV-2Disease 2019 pandemicVaccine serotypesChildren 0Baseline valuesAge groupsSerotype-specific variationPercentage changeOverall casesIncidenceNPI strategiesIPD levelAge distributionDiseaseBaselineSerotypes
2021
The Impact of Changes in Diagnostic Testing Practices on Estimates of COVID-19 Transmission in the United States
Pitzer VE, Chitwood M, Havumaki J, Menzies NA, Perniciaro S, Warren JL, Weinberger DM, Cohen T. The Impact of Changes in Diagnostic Testing Practices on Estimates of COVID-19 Transmission in the United States. American Journal Of Epidemiology 2021, 190: 1908-1917. PMID: 33831148, PMCID: PMC8083380, DOI: 10.1093/aje/kwab089.Peer-Reviewed Original ResearchConceptsSevere acute respiratory syndrome coronavirus 2Acute respiratory syndrome coronavirus 2Diagnostic testingRespiratory syndrome coronavirus 2Reproductive numberPercentage of patientsSyndrome coronavirus 2Coronavirus disease 2019Diagnostic testing practicesFraction of casesCOVID-19 transmissionEffective reproductive numberCoronavirus 2Disease 2019Testing practicesCoronavirus diseaseBasic reproductive numberLevel of interventionEstimates of R0Daily number