2019
Smoking Across the Menopausal Transition in a 10-Year Longitudinal Sample: The Role of Sex Hormones and Depressive Symptoms
Peltier MR, Flores JM, Smith PH, Roberts W, Verplaetse TL, Moore KE, Hacker R, Oberleitner LM, McKee SA. Smoking Across the Menopausal Transition in a 10-Year Longitudinal Sample: The Role of Sex Hormones and Depressive Symptoms. Nicotine & Tobacco Research 2019, 22: 872-877. PMID: 31058288, PMCID: PMC7249927, DOI: 10.1093/ntr/ntz069.Peer-Reviewed Original ResearchConceptsRegular smoking behaviorMenopausal transitionSmoking behaviorRegular smokingSex hormonesDepressive symptomsSmoking-related health consequencesMenopausal transition statusCigarette smoking ratesImpact of progesteroneRandom effects logistic regression modelHigher depression scoresMenopausal transition stageLogistic regression modelsContinued smokingSmoking cessationSmoking patternsSmoking ratesOlder womenDepression scoresSmokingWomen's healthSmoking transitionsHormone measuresHealth consequences
2018
Tobacco use during a clinical trial of mecamylamine for alcohol dependence: Medication effects on smoking and associations with reductions in drinking
Roberts W, Ralevski E, Verplaetse TL, McKee SA, Petrakis IL. Tobacco use during a clinical trial of mecamylamine for alcohol dependence: Medication effects on smoking and associations with reductions in drinking. Journal Of Substance Use And Addiction Treatment 2018, 94: 91-96. PMID: 30243424, PMCID: PMC6154389, DOI: 10.1016/j.jsat.2018.08.015.Peer-Reviewed Original ResearchConceptsAlcohol use disorderClinical trialsSmoking outcomesNicotinic acetylcholine receptor antagonistAlcohol useHigh-dependence smokersEffects of mecamylamineSubgroups of smokersAcetylcholine receptor antagonistHigh tobacco dependencePlacebo groupMedication conditionReceptor antagonistMedication effectsTobacco dependenceTobacco useTreatment respondersMecamylamineSmokingTreatment phaseUse disordersAlcohol dependenceSmokersTrialsSignificant differencesEffects of Varenicline Alone and in Combination With Low-dose Naltrexone on Alcohol-primed Smoking in Heavy-drinking Tobacco Users
Roberts W, Shi JM, Tetrault JM, McKee SA. Effects of Varenicline Alone and in Combination With Low-dose Naltrexone on Alcohol-primed Smoking in Heavy-drinking Tobacco Users. Journal Of Addiction Medicine 2018, 12: 227-233. PMID: 29438157, PMCID: PMC5970035, DOI: 10.1097/adm.0000000000000392.Peer-Reviewed Original ResearchConceptsLow-dose naltrexoneTobacco usersTreatment outcomesPlacebo-controlled human laboratory studySmoking cessation treatmentEffects of vareniclineCigarettes ad libitumHuman laboratory studiesSubjective drug effectsVarenicline monotherapyCessation medicationsMedication therapyCessation treatmentMedication armTobacco useVareniclineLow doseSmoking relapseSmokingDrug effectsSmoking outcomesSmoking behaviorNaltrexoneCarbon monoxide levelsHeavy drinkers
2016
Guanfacine alters the effect of stress and smoking on heart rate variability in regular daily smokers
Verplaetse TL, Smith PH, Smith KM, Oberleitner LM, McKee SA. Guanfacine alters the effect of stress and smoking on heart rate variability in regular daily smokers. Psychopharmacology 2016, 234: 805-813. PMID: 28028603, PMCID: PMC5309140, DOI: 10.1007/s00213-016-4517-1.Peer-Reviewed Original ResearchConceptsHeart rate variabilityRegular daily smokersEffects of guanfacineSmoking lapse behaviorHF-HRVPlacebo groupDaily smokersRate variabilitySmoking-related decreaseΑ2A-adrenergic agonistAd libitum smokingAd lib smokingHigh-frequency heart rate variabilityEffects of stressStress imageryNoradrenergic targetsVagal activityParent studySmokingGuanfacineTonic levelsPhasic changesNeutral imagery conditionsPotential mechanismsImportant markerDepression motivates quit attempts but predicts relapse: differential findings for gender from the International Tobacco Control Study
Cooper J, Borland R, McKee SA, Yong HH, Dugué PA. Depression motivates quit attempts but predicts relapse: differential findings for gender from the International Tobacco Control Study. Addiction 2016, 111: 1438-1447. PMID: 26888199, PMCID: PMC4940212, DOI: 10.1111/add.13290.Peer-Reviewed Original ResearchConceptsQuit attemptsCessation supportTobacco control studiesDepressive symptomsControl studyInternational Tobacco Control studyQuasi-experimental cohort studyMore quit attemptsMixed-effects logistic regressionLow positive affectNon-depressed counterpartsShort-term abstinenceProspective cohortCohort studyTobacco smokersDepression IndexCurrent depressionSmokersLogistic regressionFirst monthAbstinenceDepressionTelephone surveyDifferential findingsSymptoms