2023
Testing the efficacy of real-time fMRI neurofeedback for training people who smoke daily to upregulate neural responses to nondrug rewards
Chung Y, White R, Geier C, Johnston S, Smyth J, Delgado M, McKee S, Wilson S. Testing the efficacy of real-time fMRI neurofeedback for training people who smoke daily to upregulate neural responses to nondrug rewards. Cognitive, Affective, & Behavioral Neuroscience 2023, 23: 440-456. PMID: 36788202, DOI: 10.3758/s13415-023-01070-y.Peer-Reviewed Original ResearchConceptsNondrug rewardsNeurofeedback trainingNeural responsesReal-time fMRI neurofeedback trainingReal-time fMRI neurofeedbackReward-related brain activityReward-related brain areasFMRI neurofeedback trainingTraining runsSingle neurofeedback sessionFMRI neurofeedbackBrain responsesNeurofeedback researchBrain activityBOLD activationNeurofeedback sessionsSuch rewardsStriatal activityNeurofeedbackControl conditionRewardBrain areasMonetary incentivesRecent researchSmoking cessation
2020
Sex/gender differences in brain function and structure in alcohol use: A narrative review of neuroimaging findings over the last 10 years
Verplaetse TL, Cosgrove KP, Tanabe J, McKee SA. Sex/gender differences in brain function and structure in alcohol use: A narrative review of neuroimaging findings over the last 10 years. Journal Of Neuroscience Research 2020, 99: 309-323. PMID: 32333417, PMCID: PMC7584757, DOI: 10.1002/jnr.24625.Peer-Reviewed Original ResearchConceptsAlcohol use disorderAlcohol consumptionNarrative reviewBrain functionAlcohol useRisk of AUDMagnetic resonance imagingPositron emission tomographyDiffusion tensor imagingHigh-risk drinkingFunctional magnetic resonanceImaging outcomesSex/genderProblematic alcohol consumptionUse disordersResonance imagingEmission tomographySex/gender differencesRobust increaseTensor imagingBrain imaging researchRecent neuroimaging literatureWomenEvent-related potentialsNeurobiological underpinnings
2018
Pharmacotherapy for Co-Occurring Alcohol Use Disorder and Post-Traumatic Stress Disorder: Targeting the Opioidergic, Noradrenergic, Serotonergic, and GABAergic/Glutamatergic Systems.
Verplaetse TL, McKee SA, Petrakis IL. Pharmacotherapy for Co-Occurring Alcohol Use Disorder and Post-Traumatic Stress Disorder: Targeting the Opioidergic, Noradrenergic, Serotonergic, and GABAergic/Glutamatergic Systems. Alcohol Research 2018, 39: 193-205. PMID: 31198658, PMCID: PMC6561397.Peer-Reviewed Original ResearchConceptsPost-traumatic stress disorderCo-occurring alcohol use disorderAlcohol use disorderComorbid alcohol use disorderStress disorderNeurobiological systemsMaintenance of AUDUse disordersPTSD symptom severityAlcohol-motivated behaviorsAlcohol use outcomesPharmacologic treatment strategiesBrain systemsTreatment of individualsCurrent medicationsComorbid populationGlutamatergic systemPotential pharmacotherapyPharmacologic interventionsUse outcomesTreatment outcomesTreatment strategiesSingular diagnosisDual diagnosisTreatment interventions
2017
Oral Contraceptives and Cigarette Smoking: A Review of the Literature and Future Directions
Allen AM, Weinberger AH, Wetherill RR, Howe CL, McKee SA. Oral Contraceptives and Cigarette Smoking: A Review of the Literature and Future Directions. Nicotine & Tobacco Research 2017, 21: 592-601. PMID: 29165663, PMCID: PMC6468133, DOI: 10.1093/ntr/ntx258.Peer-Reviewed Original ResearchConceptsSmoking-related outcomesOC useOral contraceptivesSmoking cessation outcomesCessation outcomesOC usersNovel smoking cessation interventionUse of OCsNicotine metabolismWeight gainSmoking-related symptomsEndogenous sex hormonesSmoking cessation interventionFaster nicotine metabolismCross-sectional studyPhysiological stress responsePremenopausal smokersCurrent smokingPremenopausal womenCessation interventionsCigarette smokingEstradiol levelsSex hormonesGreater oddsFollowing keywordsNetwork Analysis of Intrinsic Functional Brain Connectivity in Male and Female Adult Smokers: A Preliminary Study
Maria M, Vanderweyen D, Camp C, Zhu X, McKee SA, Cosgrove KP, Hartwell KJ, Brady KT, Joseph JE. Network Analysis of Intrinsic Functional Brain Connectivity in Male and Female Adult Smokers: A Preliminary Study. Nicotine & Tobacco Research 2017, 20: 810-818. PMID: 29059410, PMCID: PMC5991199, DOI: 10.1093/ntr/ntx206.Peer-Reviewed Original ResearchConceptsFemale smokersMale smokersAdult smokersNicotine dependenceSalience network regionsIntrinsic functional brain connectivityFemale adult smokersHigh nicotine dependenceEffects of nicotineAge-matched controlsGraph theory measuresFunctional brain connectivityIntrinsic functional connectivitySex differencesSmoking interventionsNucleus accumbensRight insulaSmokersBrain network communicationFunctional connectivityBrain connectivityBlood oxygenFunctional magnetic resonance imaging (fMRI) experimentsConnector hubsBrain networksSex disparities in substance abuse research: Evaluating 23 years of structural neuroimaging studies
Lind KE, Gutierrez EJ, Yamamoto DJ, Regner MF, McKee SA, Tanabe J. Sex disparities in substance abuse research: Evaluating 23 years of structural neuroimaging studies. Drug And Alcohol Dependence 2017, 173: 92-98. PMID: 28212516, PMCID: PMC5581940, DOI: 10.1016/j.drugalcdep.2016.12.019.Peer-Reviewed Original ResearchConceptsSubstance use statusSex differencesBrain imaging researchSex disparitiesBrain imaging studiesStructural brain imaging studiesSubstance use studiesSubstance effectsSex effectsBrain morphometric changesStructural neuroimaging studiesSubstance use disordersUse statusNeuroimaging studiesNumber of participantsSubstance abuse researchBrain morphometryStructural brainGreater biasClinical courseSubstance abuseAnalytic approachBrain structuresProportion of studiesImaging research
2015
Antidepressant-like effects of guanfacine and sex-specific differences in effects on c-fos immunoreactivity and paired-pulse ratio in male and female mice
Mineur YS, Bentham MP, Zhou WL, Plantenga ME, McKee SA, Picciotto MR. Antidepressant-like effects of guanfacine and sex-specific differences in effects on c-fos immunoreactivity and paired-pulse ratio in male and female mice. Psychopharmacology 2015, 232: 3539-3549. PMID: 26146014, PMCID: PMC4561580, DOI: 10.1007/s00213-015-4001-3.Peer-Reviewed Original ResearchConceptsAntidepressant-like effectsPaired-pulse ratioC-Fos immunoreactivityPrefrontal cortexSwim testBrain areasRobust antidepressant-like effectsBrain regionsSex differencesMale C57BL/6J miceDepression-like behaviorEffects of guanfacineAcetylcholinesterase inhibitor physostigmineLight/dark boxBaseline sex differencesC-fos expressionDepression-like stateCritical brain regionsDifferent brain areasSex-specific changesAntidepressant efficacyCholinergic controlInhibitor physostigmineC57BL/6J miceAgonist guanfacine
2012
Sex Differences in Availability of β2*-Nicotinic Acetylcholine Receptors in Recently Abstinent Tobacco Smokers
Cosgrove KP, Esterlis I, McKee SA, Bois F, Seibyl JP, Mazure CM, Krishnan-Sarin S, Staley JK, Picciotto MR, O’Malley S. Sex Differences in Availability of β2*-Nicotinic Acetylcholine Receptors in Recently Abstinent Tobacco Smokers. JAMA Psychiatry 2012, 69: 418-427. PMID: 22474108, PMCID: PMC3508698, DOI: 10.1001/archgenpsychiatry.2011.1465.Peer-Reviewed Original ResearchMeSH KeywordsAdultAzetidinesBehavior, AddictiveBrainDepressionEstradiolFemaleFunctional NeuroimagingHumansIodine RadioisotopesMaleNicotinic AntagonistsProgesteronePyridinesRadioligand AssayReceptors, NicotinicSex CharacteristicsSmokingSubstance Withdrawal SyndromeTomography, Emission-Computed, Single-PhotonConceptsNAChR availabilityFemale smokersTobacco smokersNicotinic acetylcholine receptorsFemale nonsmokersProgesterone levelsAcetylcholine receptorsFemale sex steroid hormonesSex differencesSex steroid hormone levelsAbstinent tobacco smokersSex-matched nonsmokersTobacco smoking effectsMagnetic resonance imaging studyAge-matched malesEquilibrium distribution volumeEffects of nicotineSex steroid hormonesSteroid hormone levelsUnderlying neurochemical mechanismsResonance imaging studySingle photon emissionDays of abstinenceIA SPECTNicotine therapySex‐specific differences in GABAA‐benzodiazepine receptor availability: relationship with sensitivity to pain and tobacco smoking craving
Esterlis I, McKee SA, Kirk K, Lee D, Bois F, Stiklus SM, Seibyl JP, Krishnan‐Sarin S, O'Malley SS, Staley JK, Cosgrove KP. Sex‐specific differences in GABAA‐benzodiazepine receptor availability: relationship with sensitivity to pain and tobacco smoking craving. Addiction Biology 2012, 18: 370-378. PMID: 22353491, PMCID: PMC3378766, DOI: 10.1111/j.1369-1600.2011.00403.x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAffective SymptomsAnalysis of VarianceAnimalsBrainFemaleFlumazenilGABA ModulatorsHumansMaleMiddle AgedNicotinePain PerceptionReceptors, GABA-ASex CharacteristicsSmoking CessationSubstance Withdrawal SyndromeTobacco Use DisorderTomography, Emission-Computed, Single-PhotonYoung AdultConceptsMale smokersFemale smokersPain sensitivitySmoking interactionSmoking cravingBrain GABA levelsTobacco smoking behaviorSingle photon emissionPain symptomsLast cigaretteSmoking cessationGABA levelsSex-specific differencesTobacco smokeCigarette cravingNicotine dependenceBenzodiazepine receptorsSmokersSmoking behaviorReceptor availabilityBrain regionsCravingSex-specific regulationSignificant differencesSex differences