2023
Testing the efficacy of real-time fMRI neurofeedback for training people who smoke daily to upregulate neural responses to nondrug rewards
Chung Y, White R, Geier C, Johnston S, Smyth J, Delgado M, McKee S, Wilson S. Testing the efficacy of real-time fMRI neurofeedback for training people who smoke daily to upregulate neural responses to nondrug rewards. Cognitive, Affective, & Behavioral Neuroscience 2023, 23: 440-456. PMID: 36788202, DOI: 10.3758/s13415-023-01070-y.Peer-Reviewed Original ResearchConceptsNondrug rewardsNeurofeedback trainingNeural responsesReal-time fMRI neurofeedback trainingReal-time fMRI neurofeedbackReward-related brain activityReward-related brain areasFMRI neurofeedback trainingTraining runsSingle neurofeedback sessionFMRI neurofeedbackBrain responsesNeurofeedback researchBrain activityBOLD activationNeurofeedback sessionsSuch rewardsStriatal activityNeurofeedbackControl conditionRewardBrain areasMonetary incentivesRecent researchSmoking cessation
2019
Commentary on Tosun et al. (2019): Dynamic changes in sex hormones and smoking cessation
Peltier MR, McKee SA. Commentary on Tosun et al. (2019): Dynamic changes in sex hormones and smoking cessation. Addiction 2019, 114: 1814-1815. PMID: 31347245, PMCID: PMC6732031, DOI: 10.1111/add.14728.Peer-Reviewed Original ResearchUse of Mentholated Cigarettes and Likelihood of Smoking Cessation in the United States: A Meta-Analysis
Smith PH, Assefa B, Kainth S, Salas-Ramirez KY, McKee SA, Giovino GA. Use of Mentholated Cigarettes and Likelihood of Smoking Cessation in the United States: A Meta-Analysis. Nicotine & Tobacco Research 2019, 22: 307-316. PMID: 31204787, PMCID: PMC7161928, DOI: 10.1093/ntr/ntz067.Peer-Reviewed Original ResearchConceptsAfrican American smokersSmoking cessationMenthol cigarette useAmerican smokersMenthol useUS smokersCigarette useComprehensive tobacco control effortCross-sectional studyNon-menthol usersPublic health benefitsTobacco control effortsEffect sizeBlack/African AmericanMentholated cigarettesMenthol banLower oddsSmokersMeta-AnalysisSignificant associationCessationLower likelihoodHealth benefitsQuantitative summaryStudy sample
2018
Electronic Cigarette Use and Risk of Harmful Alcohol Consumption in the U.S. Population
Roberts W, Moore K, Peltier MR, Verplaetse TL, Oberleitner L, Hacker R, McKee SA. Electronic Cigarette Use and Risk of Harmful Alcohol Consumption in the U.S. Population. Alcohol Clinical And Experimental Research 2018, 42: 2385-2393. PMID: 30222189, PMCID: PMC6286236, DOI: 10.1111/acer.13889.Peer-Reviewed Original ResearchConceptsAlcohol use disorderE-cigarette useHarmful alcohol useE-cigarette usersHarmful alcohol consumptionAlcohol use outcomesElectronic cigarette useCigarette useAlcohol useE-cigarettesUse outcomesNondaily usersUse disordersAlcohol consumptionPast-year e-cigarette useHazardous drinkingAssociated Disabilities Interview ScheduleCigarette/e-cigarette useU.S. populationRelated Conditions Wave IIIDrinking frequencyTobacco cigarette useNational Epidemiologic SurveyBinge drinking frequencyQuantity/frequencyA preliminary investigation into the effects of doxazosin on cognitive functioning in tobacco‐deprived and ‐satiated smokers
Roberts W, Verplaetse TL, Moore KE, Oberleitner LM, McKee SA. A preliminary investigation into the effects of doxazosin on cognitive functioning in tobacco‐deprived and ‐satiated smokers. Human Psychopharmacology Clinical And Experimental 2018, 33: e2660. PMID: 29878501, PMCID: PMC5995328, DOI: 10.1002/hup.2660.Peer-Reviewed Original ResearchConceptsContinuous performance taskInhibitory controlCognitive functioningPerformance taskTobacco withdrawalEffects of doxazosinSustained attentionCognitive performanceWithdrawal symptomsCognitive AssessmentSmoking outcomesMost measuresSelf-reported withdrawal symptomsReaction timeTaskParticipantsFunctioningPredrug levelsΑ1 antagonistTitration periodGreater improvementDoxazosinSmokingSymptomsPreliminary investigationPilot investigation of the effect of carvedilol on stress-precipitated smoking-lapse behavior
Verplaetse TL, Weinberger AH, Ashare RL, Pittman BP, Shi JM, Tetrault JM, Lavery M, McKee SA. Pilot investigation of the effect of carvedilol on stress-precipitated smoking-lapse behavior. Journal Of Psychopharmacology 2018, 32: 1003-1009. PMID: 29692206, PMCID: PMC6258014, DOI: 10.1177/0269881118767647.Peer-Reviewed Original ResearchConceptsEffects of carvedilolSmoking lapse behaviorAdrenergic antagonistsTobacco cravingSmoking outcomesPhysiologic reactivitySystolic blood pressureNumber of cigarettesNicotine-motivated behaviors× time effectSelf-administration periodEffects of α1Human laboratory modelNicotine-deprived smokersPlacebo groupBlood pressureAdrenergic antagonismMedication conditionClinical indicationsNoradrenergic systemSubsequent smokingHeart rateProperties of drugsSmokingCarvedilol
2017
Network Analysis of Intrinsic Functional Brain Connectivity in Male and Female Adult Smokers: A Preliminary Study
Maria M, Vanderweyen D, Camp C, Zhu X, McKee SA, Cosgrove KP, Hartwell KJ, Brady KT, Joseph JE. Network Analysis of Intrinsic Functional Brain Connectivity in Male and Female Adult Smokers: A Preliminary Study. Nicotine & Tobacco Research 2017, 20: 810-818. PMID: 29059410, PMCID: PMC5991199, DOI: 10.1093/ntr/ntx206.Peer-Reviewed Original ResearchConceptsFemale smokersMale smokersAdult smokersNicotine dependenceSalience network regionsIntrinsic functional brain connectivityFemale adult smokersHigh nicotine dependenceEffects of nicotineAge-matched controlsGraph theory measuresFunctional brain connectivityIntrinsic functional connectivitySex differencesSmoking interventionsNucleus accumbensRight insulaSmokersBrain network communicationFunctional connectivityBrain connectivityBlood oxygenFunctional magnetic resonance imaging (fMRI) experimentsConnector hubsBrain networksGender differences in the real-world effectiveness of smoking cessation medications: Findings from the 2010–2011 Tobacco Use Supplement to the Current Population Survey
Smith PH, Zhang J, Weinberger AH, Mazure CM, McKee SA. Gender differences in the real-world effectiveness of smoking cessation medications: Findings from the 2010–2011 Tobacco Use Supplement to the Current Population Survey. Drug And Alcohol Dependence 2017, 178: 485-491. PMID: 28715776, PMCID: PMC6779031, DOI: 10.1016/j.drugalcdep.2017.05.046.Peer-Reviewed Original ResearchConceptsTransdermal nicotine patchUnassisted quit attemptsClinical trial dataTobacco Use SupplementQuit attemptsTrial dataClinical trial findingsReal-world effectivenessSample of smokersGender differencesRelevant gender differencesCessation optionsCessation medicationsCessation pharmacotherapyNicotine patchMedication interactionsSmoking cessationPotential confoundersTrial findingsVareniclineComparative effectivenessPropensity scoreCross-sectional dataWomenMedicationsMaternal smoking and autism spectrum disorder: meta-analysis with population smoking metrics as moderators
Jung Y, Lee AM, McKee SA, Picciotto MR. Maternal smoking and autism spectrum disorder: meta-analysis with population smoking metrics as moderators. Scientific Reports 2017, 7: 4315. PMID: 28659613, PMCID: PMC5489536, DOI: 10.1038/s41598-017-04413-1.Peer-Reviewed Original ResearchConceptsMale smoking prevalenceMaternal smokingNicotine exposureSmoking prevalenceAdult male smoking prevalenceSignificant associationPostnatal nicotine exposureUtero nicotine exposureAutism spectrum disorderRandom-effects modelWorld Health Organization dataMeta-regression analysisSmoking metricsSmoke exposureSecondhand smokingPooled ORsObservational studySpectrum disorderSmokingBrain developmentControl participantsPrevalenceASD riskExposureAssociationEffects of varenicline on alcohol cue reactivity in heavy drinkers
Roberts W, Harrison ELR, McKee SA. Effects of varenicline on alcohol cue reactivity in heavy drinkers. Psychopharmacology 2017, 234: 2737-2745. PMID: 28600734, PMCID: PMC5709183, DOI: 10.1007/s00213-017-4667-9.Peer-Reviewed Original ResearchConceptsEffects of vareniclineHuman laboratory studiesAlcohol use disorderAlcohol cue reactivityHeavy drinkersUse disordersPlacebo-controlled human laboratory studyCue exposureAlcohol useCue reactivityUse of vareniclineFront-line treatmentCue-induced alcohol cravingAlcohol cue exposureTitration periodCue-reactivity paradigmMedication groupPharmacological treatmentMedication effectsAdult smokersTobacco cravingVareniclineMethodsAs partLarge seriesAlcohol cravingEffect of doxazosin on stress reactivity and the ability to resist smoking
Verplaetse TL, Weinberger AH, Oberleitner LM, Smith KM, Pittman BP, Shi JM, Tetrault JM, Lavery ME, Picciotto MR, McKee SA. Effect of doxazosin on stress reactivity and the ability to resist smoking. Journal Of Psychopharmacology 2017, 31: 830-840. PMID: 28440105, PMCID: PMC5823502, DOI: 10.1177/0269881117699603.Peer-Reviewed Original ResearchConceptsTobacco cravingCortisol levelsSubsequent ad libitum smokingEffects of doxazosinAd libitum smokingNumber of cigarettesNicotine-motivated behaviorsSmoking lapse behaviorΑ1-adrenergic antagonistNicotine-deprived smokersTitration periodPreclinical findingsSmoking cessationNoradrenergic systemTreatment strategiesDoxazosinSmoking behaviorSmokingHuman laboratoryPhysiologic reactivityPilot studyStress reactivityEffects of stressCigarettesStress imageryTime Trends in Smoking Onset by Sex and Race/Ethnicity Among Adolescents and Young Adults: Findings From the 2006–2013 National Survey on Drug Use and Health
Thompson AB, Mowery PD, Tebes JK, McKee SA. Time Trends in Smoking Onset by Sex and Race/Ethnicity Among Adolescents and Young Adults: Findings From the 2006–2013 National Survey on Drug Use and Health. Nicotine & Tobacco Research 2017, 20: 312-320. PMID: 28339616, PMCID: PMC5896447, DOI: 10.1093/ntr/ntx010.Peer-Reviewed Original ResearchConceptsSmoking onsetYoung adult malesYoung adultsDrug useLog-binomial regression modelsAnnual declineTobacco-related health disparitiesTime trendsRate of onsetNational surveyTobacco control policiesNumber of adolescentsRace/ethnicityYoung adult femalesRegression modelsAdult malesNew smokersAdult smokingYoung adult yearsEthnic groupsHealth disparitiesGreater riskMore effective strategiesAdultsAdolescents
2016
Guanfacine alters the effect of stress and smoking on heart rate variability in regular daily smokers
Verplaetse TL, Smith PH, Smith KM, Oberleitner LM, McKee SA. Guanfacine alters the effect of stress and smoking on heart rate variability in regular daily smokers. Psychopharmacology 2016, 234: 805-813. PMID: 28028603, PMCID: PMC5309140, DOI: 10.1007/s00213-016-4517-1.Peer-Reviewed Original ResearchConceptsHeart rate variabilityRegular daily smokersEffects of guanfacineSmoking lapse behaviorHF-HRVPlacebo groupDaily smokersRate variabilitySmoking-related decreaseΑ2A-adrenergic agonistAd libitum smokingAd lib smokingHigh-frequency heart rate variabilityEffects of stressStress imageryNoradrenergic targetsVagal activityParent studySmokingGuanfacineTonic levelsPhasic changesNeutral imagery conditionsPotential mechanismsImportant markerSex/gender differences in smoking cessation: A review
Smith PH, Bessette AJ, Weinberger AH, Sheffer CE, McKee SA. Sex/gender differences in smoking cessation: A review. Preventive Medicine 2016, 92: 135-140. PMID: 27471021, PMCID: PMC5085924, DOI: 10.1016/j.ypmed.2016.07.013.Peer-Reviewed Original ResearchConceptsProspective observational studyObservational studyCross-sectional investigationSex/gender differencesSmoking cessationEffectiveness trialCommunity-based interventionsLong-term abstinenceGender differencesSmoker prevalenceEfficacy trialsOutcome assessmentTreatment studiesEpidemiological investigationsMeet criteriaStudy sampleTrialsCessationWomenRelapseSmokingBio-psychoMenQualitative reviewReviewSex Differences in Smoking Cessation Pharmacotherapy Comparative Efficacy: A Network Meta-analysis
Smith PH, Weinberger AH, Zhang J, Emme E, Mazure CM, McKee SA. Sex Differences in Smoking Cessation Pharmacotherapy Comparative Efficacy: A Network Meta-analysis. Nicotine & Tobacco Research 2016, 19: 273-281. PMID: 27613893, PMCID: PMC5939704, DOI: 10.1093/ntr/ntw144.Peer-Reviewed Original ResearchConceptsTransdermal nicotineSmoking cessationBupropion SRComparative efficacyFirst option treatmentSustained release bupropionPlacebo-controlled trialSex differencesCigarette smoking cessationNetwork Meta-AnalysisRelease bupropionCessation pharmacotherapyOption treatmentGeneral community sampleCigarette smokersQuit ratesVarenicline's efficacyPharmacological interventionsVareniclineBupropionNicotine addictionMeta-AnalysisPlaceboSimilar outcomesSignificant sex differencesAssociations of Gender, Smoking, and Stress with Transitions in Major Depression Diagnoses.
Verplaetse TL, Smith PH, Pittman BP, Mazure CM, McKee SA. Associations of Gender, Smoking, and Stress with Transitions in Major Depression Diagnoses. The Yale Journal Of Biology And Medicine 2016, 89: 123-9. PMID: 27354839, PMCID: PMC4918874.Peer-Reviewed Original ResearchConceptsMajor depression diagnosisFormer smokersDepression diagnosisMDD diagnosisMore stressful eventsStressful eventsFormer cigarette smokersU.S. National Epidemiologic SurveyCigarette smoking statusNational Epidemiologic SurveyAssociation of genderCurrent smokingSmoking statusCigarette smokersClinical assessmentDepression riskEpidemiologic SurveyLife event stressRelated conditionsSmokersSmokingDiagnosisBiological underpinningsEvent stressHigh ratePotential Unintended Consequences of Electronic Cigarette Use in Drinking Venues
Young-Wolff KC, McKee SA. Potential Unintended Consequences of Electronic Cigarette Use in Drinking Venues. Alcohol Clinical And Experimental Research 2016, 40: 939-941. PMID: 27062550, DOI: 10.1111/acer.13050.Peer-Reviewed Original ResearchDepression motivates quit attempts but predicts relapse: differential findings for gender from the International Tobacco Control Study
Cooper J, Borland R, McKee SA, Yong HH, Dugué PA. Depression motivates quit attempts but predicts relapse: differential findings for gender from the International Tobacco Control Study. Addiction 2016, 111: 1438-1447. PMID: 26888199, PMCID: PMC4940212, DOI: 10.1111/add.13290.Peer-Reviewed Original ResearchConceptsQuit attemptsCessation supportTobacco control studiesDepressive symptomsControl studyInternational Tobacco Control studyQuasi-experimental cohort studyMore quit attemptsMixed-effects logistic regressionLow positive affectNon-depressed counterpartsShort-term abstinenceProspective cohortCohort studyTobacco smokersDepression IndexCurrent depressionSmokersLogistic regressionFirst monthAbstinenceDepressionTelephone surveyDifferential findingsSymptoms
2015
Transcranial Direct Current Brain Stimulation Increases Ability to Resist Smoking
Falcone M, Bernardo L, Ashare RL, Hamilton R, Faseyitan O, McKee SA, Loughead J, Lerman C. Transcranial Direct Current Brain Stimulation Increases Ability to Resist Smoking. Brain Stimulation 2015, 9: 191-196. PMID: 26572280, PMCID: PMC4789149, DOI: 10.1016/j.brs.2015.10.004.Peer-Reviewed Original ResearchConceptsTranscranial direct current stimulationDorsolateral prefrontal cortexLeft dorsolateral prefrontal cortexActive transcranial direct current stimulationMA anodal stimulationAnodal stimulationSmoking cessation treatmentSmoking behavior changeSelf-reported smokingDirect current stimulationSecondary outcomesCessation treatmentWashout periodFirst cigaretteCigarette cravingOvernight abstinenceTDCS sessionsSmoking sessionCigarette consumptionSmokingTherapeutic potentialCurrent stimulationPrefrontal cortexCognitive control circuitsCathodal stimulationCorrelates of smoking status among women experiencing intimate partner violence: Substance use, posttraumatic stress, and coping
Sullivan TP, Flanagan JC, Dudley DN, Holt LJ, Mazure CM, McKee SA. Correlates of smoking status among women experiencing intimate partner violence: Substance use, posttraumatic stress, and coping. American Journal On Addictions 2015, 24: 546-553. PMID: 26249027, PMCID: PMC4600351, DOI: 10.1111/ajad.12261.Peer-Reviewed Original ResearchConceptsSymptom severitySmoking statusIntimate partner violenceAlcohol problem severityPopulation of womenProblem severityDaily smoking statusIPV-victimized womenPsychiatric symptom severityCessation interventionsCigarette smokingDaily smokersPartner violencePhysical intimate partner violenceSeverity of useCessation researchWomen's healthPosttraumatic stress symptom severityStress symptom severityDrug useNegative sequelaeContext of IPVLogistic regressionSmokersSeverity