2018
A preliminary investigation into the effects of doxazosin on cognitive functioning in tobacco‐deprived and ‐satiated smokers
Roberts W, Verplaetse TL, Moore KE, Oberleitner LM, McKee SA. A preliminary investigation into the effects of doxazosin on cognitive functioning in tobacco‐deprived and ‐satiated smokers. Human Psychopharmacology Clinical And Experimental 2018, 33: e2660. PMID: 29878501, PMCID: PMC5995328, DOI: 10.1002/hup.2660.Peer-Reviewed Original ResearchConceptsContinuous performance taskInhibitory controlCognitive functioningPerformance taskTobacco withdrawalEffects of doxazosinSustained attentionCognitive performanceWithdrawal symptomsCognitive AssessmentSmoking outcomesMost measuresSelf-reported withdrawal symptomsReaction timeTaskParticipantsFunctioningPredrug levelsΑ1 antagonistTitration periodGreater improvementDoxazosinSmokingSymptomsPreliminary investigation
2012
Sex differences in stimulus expectancy and pharmacologic effects of a moderate dose of alcohol on smoking lapse risk in a laboratory analogue study
Kahler CW, Metrik J, Spillane NS, Leventhal AM, McKee SA, Tidey JW, McGeary JE, Knopik VS, Rohsenow DJ. Sex differences in stimulus expectancy and pharmacologic effects of a moderate dose of alcohol on smoking lapse risk in a laboratory analogue study. Psychopharmacology 2012, 222: 71-80. PMID: 22227611, PMCID: PMC3687530, DOI: 10.1007/s00213-011-2624-6.Peer-Reviewed Original ResearchConceptsInstruction conditionPharmacologic effectsStimulus expectancyQuit smoking attemptsDirect pharmacologic effectInitial lapseHeavy alcohol drinkersLapse riskLaboratory analog studiesPlacebo designBeverage contentSmoking attemptsAnalogue studyAlcohol drinkersGreater satisfactionModerate doseSex differencesSmoking behaviorPharmacological effectsSmokingNonalcoholic beveragesTaskCondition effectsSatisfactionInstruction
2009
Nicotine Deprivation and Trait Impulsivity Affect Smokers' Performance on Cognitive Tasks of Inhibition and Attention
Harrison EL, Coppola S, McKee SA. Nicotine Deprivation and Trait Impulsivity Affect Smokers' Performance on Cognitive Tasks of Inhibition and Attention. Experimental And Clinical Psychopharmacology 2009, 17: 91-98. PMID: 19331485, PMCID: PMC2863308, DOI: 10.1037/a0015657.Peer-Reviewed Original ResearchConceptsCognitive processingNicotine deprivationImpulsive smokersTrait impulsivityGo/No-Go taskBarratt Impulsiveness ScaleCognitive tasksInhibitory controlPerformance decrementsImpulsiveness ScaleTask IISubjects designImpulsivityGreater impairmentDaily smokersReaction timeDeprivation conditionsMixed model regression analysisTaskProcessingRelapse riskImpairmentSignificant deprivationImpulsivenessDeprivation