2017
Effect of doxazosin on stress reactivity and the ability to resist smoking
Verplaetse TL, Weinberger AH, Oberleitner LM, Smith KM, Pittman BP, Shi JM, Tetrault JM, Lavery ME, Picciotto MR, McKee SA. Effect of doxazosin on stress reactivity and the ability to resist smoking. Journal Of Psychopharmacology 2017, 31: 830-840. PMID: 28440105, PMCID: PMC5823502, DOI: 10.1177/0269881117699603.Peer-Reviewed Original ResearchConceptsTobacco cravingCortisol levelsSubsequent ad libitum smokingEffects of doxazosinAd libitum smokingNumber of cigarettesNicotine-motivated behaviorsSmoking lapse behaviorΑ1-adrenergic antagonistNicotine-deprived smokersTitration periodPreclinical findingsSmoking cessationNoradrenergic systemTreatment strategiesDoxazosinSmoking behaviorSmokingHuman laboratoryPhysiologic reactivityPilot studyStress reactivityEffects of stressCigarettesStress imagery
2015
The Yale Craving Scale: Development and psychometric properties
Rojewski AM, Morean ME, Toll BA, McKee SA, Krishnan-Sarin S, Green BG, Bartoshuk LM, O’Malley S. The Yale Craving Scale: Development and psychometric properties. Drug And Alcohol Dependence 2015, 154: 158-166. PMID: 26183404, PMCID: PMC4834029, DOI: 10.1016/j.drugalcdep.2015.06.040.Peer-Reviewed Original ResearchConceptsCeiling effectsPsychometric evaluationCraving ScaleDrinking scoresTreatment-seeking smokersInternal consistencyGood internal consistencyHeavy drinkersSmokingGroup comparisonsDrinking urgesStudy sampleDrinking outcomesSensation intensitySubjective cravingLabeled Magnitude ScaleCigarettesPsychometric propertiesScoresCurrent studyLatent factor structureTest-criterion relationshipsSound scaleSmokersDependent population
2011
Gender Differences in Smoking Following an Implicit Mood Induction
Weinberger AH, McKee SA. Gender Differences in Smoking Following an Implicit Mood Induction. Nicotine & Tobacco Research 2011, 14: 621-625. PMID: 21908458, PMCID: PMC3430446, DOI: 10.1093/ntr/ntr198.Peer-Reviewed Original ResearchConceptsNumber of cigarettesSmoking behaviorNegative mood inductionMood inductionFemale smokersNegative affectMood conditionGender differencesPositive mood inductionNeutral mood conditionAdult smokersSmoking maintenanceSmokersSmokingTreatment developmentMood manipulationNegative moodRole of genderInductionCigarettesLaboratory sessionsAffectDifferencesThe role of smoking expectancies in the relationship between PTSD symptoms and smoking behavior among women exposed to intimate partner violence
Ashare RL, Weinberger AH, McKee SA, Sullivan TP. The role of smoking expectancies in the relationship between PTSD symptoms and smoking behavior among women exposed to intimate partner violence. Addictive Behaviors 2011, 36: 1333-1336. PMID: 21849230, PMCID: PMC3179791, DOI: 10.1016/j.addbeh.2011.07.022.Peer-Reviewed Original ResearchConceptsNicotine dependenceSmoking behaviorPTSD symptomsSmoking expectanciesIPV-exposed womenIntimate partner violencePTSD re-experiencing symptomsPublic health problemPTSD arousal symptomsHigh rateNegative health consequencesTobacco smokingPartner violencePTSD symptom clustersRe-experiencing symptomsHealth problemsSmokingSymptomsSymptom clustersHealth consequencesTreatment developmentCigarettesArousal symptomsWomenLast month
2010
Brain β2*-nicotinic acetylcholine receptor occupancy after use of a nicotine inhaler
Esterlis I, Mitsis EM, Batis JC, Bois F, Picciotto MR, Stiklus SM, Kloczynski T, Perry E, Seibyl JP, McKee S, Staley JK, Cosgrove KP. Brain β2*-nicotinic acetylcholine receptor occupancy after use of a nicotine inhaler. The International Journal Of Neuropsychopharmacology 2010, 14: 389-398. PMID: 21029513, PMCID: PMC3510008, DOI: 10.1017/s1461145710001227.Peer-Reviewed Original ResearchConceptsNicotine inhalerWithdrawal symptomsReceptor occupancyTobacco smokingLow nicotine cigarettesAdministration of nicotineHigh receptor occupancyDoses of nicotineNicotinic acetylcholine receptorsInhaler useTobacco smokersBaseline scanRegular cigarettesInhalerConstant infusionAcetylcholine receptorsSPECT studiesCigarettesSymptomsBeta 2Significant decreaseNicotineSignificant differencesSmokingNAChRsNicotine and food deprivation decrease the ability to resist smoking
Leeman RF, O’Malley S, White MA, McKee SA. Nicotine and food deprivation decrease the ability to resist smoking. Psychopharmacology 2010, 212: 25-32. PMID: 20585761, PMCID: PMC3111597, DOI: 10.1007/s00213-010-1902-z.Peer-Reviewed Original ResearchConceptsSubsequent ad libitum smokingNicotine deprivationAd libitum smokingFood deprivationSmoking lapse behaviorSelf-administration periodEffect of foodSmokers' abilityMore cigarettesFirst cigaretteHuman laboratory paradigmDaily smokersTobacco cravingFood intakeCessation failureSmokingConclusionsThese findingsFood cuesMonetary reinforcementCigarettesNicotineSex differencesDeprivationLaboratory sessionsOutcomesAlcohol expectancy increases positive responses to cigarettes in young, escalating smokers
McKee SA, Harrison EL, Shi J. Alcohol expectancy increases positive responses to cigarettes in young, escalating smokers. Psychopharmacology 2010, 210: 355-364. PMID: 20352411, PMCID: PMC2874601, DOI: 10.1007/s00213-010-1831-x.Peer-Reviewed Original ResearchConceptsSmoking behaviorAd lib smoking behaviorExpectation of alcoholHeavy-drinking young adultsDaily cigarette useExperience of smokingSmoking patternsNondaily smokersSubsequent smokingSmokingSingle cigaretteCigarette useAge groupsAlcohol altersSmokersSubjective effectsYoung adultsYoung adulthoodCigarettesPlaceboHigh rateSubjective reactivitySubjective responsesPrimary aimPositive response
2009
Experimenting and daily smokers: Episodic patterns of alcohol and cigarette use
Harrison EL, Hinson RE, McKee SA. Experimenting and daily smokers: Episodic patterns of alcohol and cigarette use. Addictive Behaviors 2009, 34: 484-486. PMID: 19176271, PMCID: PMC2865434, DOI: 10.1016/j.addbeh.2008.12.013.Peer-Reviewed Original ResearchConceptsCigarette useEpisodic patternPatterns of alcoholBinge levelsConsumption of drinksSmoking historyCigarette smokingTobacco dependenceDaily smokersNicotine dependenceSmoking episodesConcurrent alcoholSmokersSmokingMore drinksAlcohol useGroup differencesDrinksTypical drinkingDrinkingTotal numberHoursSelf-reported pleasureCigarettesCollege-age sample
2008
Developing human laboratory models of smoking lapse behavior for medication screening
McKee SA. Developing human laboratory models of smoking lapse behavior for medication screening. Addiction Biology 2008, 14: 99-107. PMID: 18855800, PMCID: PMC2732001, DOI: 10.1111/j.1369-1600.2008.00135.x.Peer-Reviewed Original ResearchConceptsMedication screeningHuman laboratory modelSmoking behaviorMedication developmentSubsequent ad libitum smokingAd libitum smokingDrug Administration approvalSelf-administration sessionsMedication signalsCessation medicationsLapse behaviorAdministration approvalFirst cigaretteAbstinence outcomesQuit attemptsSmoking relapseUS FoodSmokingSmokersRelapseImportant targetTranslational workCigarettesScreeningMechanistic evaluation[123I]5-IA-85380 SPECT imaging nicotine occupancy of brain β2-nicotinic acetylcholine receptors after smoking low nicotine and nicotine-free cigarettes
Esterlis I, Batis J, Cosgrove K, Bois F, McKee S, Kloczynski T, Stiklus S, O'Malley S, Perry E, Tamagnan G, Seibyl J, Staley J. [123I]5-IA-85380 SPECT imaging nicotine occupancy of brain β2-nicotinic acetylcholine receptors after smoking low nicotine and nicotine-free cigarettes. NeuroImage 2008, 41: t182. DOI: 10.1016/j.neuroimage.2008.04.149.Peer-Reviewed Original Research
2007
Young adult non-daily smokers: Patterns of alcohol and cigarette use
Harrison EL, McKee SA. Young adult non-daily smokers: Patterns of alcohol and cigarette use. Addictive Behaviors 2007, 33: 668-674. PMID: 18093745, PMCID: PMC2349092, DOI: 10.1016/j.addbeh.2007.11.012.Peer-Reviewed Original ResearchSubjective reactivity to the first cigarette of the day as a predictor of smoking relapse: A preliminary study
Toll BA, Schepis TS, O’Malley S, McKee SA, Krishnan-Sarin S. Subjective reactivity to the first cigarette of the day as a predictor of smoking relapse: A preliminary study. Drug And Alcohol Dependence 2007, 89: 302-305. PMID: 17320313, PMCID: PMC2475673, DOI: 10.1016/j.drugalcdep.2007.01.011.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAffectAgedAntidepressive Agents, Second-GenerationBehavior TherapyBupropionCircadian RhythmDelayed-Action PreparationsFemaleHumansMaleMiddle AgedMotivationNicotineOutcome Assessment, Health CarePrognosisSecondary PreventionSmokingSmoking CessationSubstance Withdrawal SyndromeSurveys and QuestionnairesTobacco Use DisorderConceptsFirst cigaretteSmoking relapseEnd of treatmentCessation treatment outcomeInitial cigaretteWithdrawal symptomsClinical trialsQuit dayTreatment outcomesNovel predictorRelapseCigarettesPreliminary studyTime pointsGreater decreaseCravingSubjective responsesSubjective reactivityDaysFuture studiesSignificant changesWithdrawalPredictorsResponseBupropion
2006
Gender and weight concerns in adolescent smokers
Cavallo DA, Duhig AM, McKee S, Krishnan-Sarin S. Gender and weight concerns in adolescent smokers. Addictive Behaviors 2006, 31: 2140-2146. PMID: 16567058, DOI: 10.1016/j.addbeh.2006.02.021.Peer-Reviewed Original ResearchConceptsBody mass indexAdolescent smokersWeight concernsSmoking-specific weight concernsYears of smokingDaily cigarette useSmoking controls weightAdolescent daily smokersMass indexMore cigarettesDaily smokersSmokingCigarette useImportant gender differencesSmokersInfluence of genderCigarettesMalesGender differencesSignificant relationshipFemalesGenderControl weightWeightSmoking for weight control: Effect of priming for body image in female restrained eaters
McKee SA, Nhean S, Hinson RE, Mase T. Smoking for weight control: Effect of priming for body image in female restrained eaters. Addictive Behaviors 2006, 31: 2319-2323. PMID: 16567057, DOI: 10.1016/j.addbeh.2006.02.014.Peer-Reviewed Original Research
2005
Daily patterns of alcohol, cigarette, and marijuana use in adolescent smokers and nonsmokers
Duhig AM, Cavallo DA, McKee SA, George TP, Krishnan-Sarin S. Daily patterns of alcohol, cigarette, and marijuana use in adolescent smokers and nonsmokers. Addictive Behaviors 2005, 30: 271-283. PMID: 15621398, DOI: 10.1016/j.addbeh.2004.05.016.Peer-Reviewed Original ResearchConceptsFrequent daily useAdolescent smokersMarijuana useAdolescent cigarette smokersDaily usePatterns of alcoholMale smokersCigarette smokersSmokersClinical interventionsNonsmokersFuture researchPast monthMarijuanaMore daysSame dayCigarettesSignificant differencesOne-fifthDaily use patternsDaysMonths
2004
Revisiting the Factor Structure of the Questionnaire on Smoking Urges
Toll BA, McKee SA, Krishnan-Sarin S, O'Malley SS. Revisiting the Factor Structure of the Questionnaire on Smoking Urges. Psychological Assessment 2004, 16: 391-395. PMID: 15584799, PMCID: PMC2527732, DOI: 10.1037/1040-3590.16.4.391.Peer-Reviewed Original Research