Modeling ability to resist alcohol in the human laboratory: A pilot study
Sloan M, Sells J, Vaughan C, Morris J, Ortega N, Sundar S, Soundararajan S, Stangl B, Gowin J, Chawla S, Diazgranados N, McKee S, Waters A, Ramchandani V. Modeling ability to resist alcohol in the human laboratory: A pilot study. Drug And Alcohol Dependence Reports 2022, 5: 100105. PMID: 36844167, PMCID: PMC9948911, DOI: 10.1016/j.dadr.2022.100105.Peer-Reviewed Original ResearchAlcohol self-administration paradigmSelf-administration paradigmCox proportional hazards regressionAlcohol usePilot studyLow-risk consumptionRisk of lapseHalf of patientsProportional hazards regressionSelf-administer alcoholAlcohol use disorderAlcohol intakeHazards regressionPriming doseUse disordersScale scoreHeavy drinkersHuman laboratoryImpaired controlInitial exposureCharacteristics of individualsPreliminary evidenceControl Scale scoresFuture studiesIndividualsSex differences in stress-induced alcohol intake: a review of preclinical studies focused on amygdala and inflammatory pathways
Mineur YS, Garcia-Rivas V, Thomas MA, Soares AR, McKee SA, Picciotto MR. Sex differences in stress-induced alcohol intake: a review of preclinical studies focused on amygdala and inflammatory pathways. Psychopharmacology 2022, 239: 2041-2061. PMID: 35359158, PMCID: PMC9704113, DOI: 10.1007/s00213-022-06120-w.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsAlcohol intakeInflammatory pathwaysAlcohol drinkingStress-induced alcohol drinkingSex differencesSex-dependent effectsStress-induced alcoholEffects of stressPreclinical behavioral modelsAlcohol-dependent behaviorsMicroglial activationClinical studiesPreclinical studiesInflammatory signalingNeuronal functionAlcohol seekingIntakeFuture studiesDrinkingDifferencesAmygdalaPathwayStudyWomen