2003
CYP2C9exon 4 mutations and warfarin dose phenotype in Asians
Rettie A, Tai G, Veenstra D, Farin F, Srinouanprachan S, Lin Y, Thummel K, Hines R. CYP2C9exon 4 mutations and warfarin dose phenotype in Asians. Blood 2003, 101: 2896-2897. PMID: 12642346, DOI: 10.1182/blood-2002-11-3452.Peer-Reviewed Original Research
2002
Alternative Processing of the Human FMO6 Gene Renders Transcripts Incapable of Encoding a Functional Flavin-Containing Monooxygenase
Hines R, Hopp K, Franco J, Saeian K, Begun F. Alternative Processing of the Human FMO6 Gene Renders Transcripts Incapable of Encoding a Functional Flavin-Containing Monooxygenase. Molecular Pharmacology 2002, 62: 320-325. PMID: 12130684, DOI: 10.1124/mol.62.2.320.Peer-Reviewed Original Research
1997
Further Characterization of the Major and Minor RabbitFMO1Promoters and Identification of both Positive and Negative Distal Regulatory Elements
Luo Z, Hines R. Further Characterization of the Major and Minor RabbitFMO1Promoters and Identification of both Positive and Negative Distal Regulatory Elements. Archives Of Biochemistry And Biophysics 1997, 346: 96-104. PMID: 9328289, DOI: 10.1006/abbi.1997.0287.Peer-Reviewed Original ResearchConceptsRegulatory domainRegulatory sequencesRegulatory regionsSpecific DNA/protein complexesDNA/protein complexesUpstream regulatory domainsDistal regulatory elementsNegative regulatory sequencesPositive regulatory domainUpstream regulatory sequencesNegative regulatory regionPositive regulatory regionBasal transcriptional activityProtein complexesTranscription initiationHepG2 nuclear extractsDeletion mutantsMature transcriptsDeletion analysisRegulatory elementsLeader sequenceMinor promoterTransient expressionUpstream promoterTranscriptional activity
1996
Identification of Multiple Rabbit Flavin-Containing Monooxygenase Form 1 (FMO1) Gene Promoters and Observation of Tissue-Specific DNase I Hypersensitive Sites
Luo Z, Hines R. Identification of Multiple Rabbit Flavin-Containing Monooxygenase Form 1 (FMO1) Gene Promoters and Observation of Tissue-Specific DNase I Hypersensitive Sites. Archives Of Biochemistry And Biophysics 1996, 336: 251-260. PMID: 8954572, DOI: 10.1006/abbi.1996.0555.Peer-Reviewed Original Research