Variation in Induction of Human Placental CYP2E1: Possible Role in Susceptibility to Fetal Alcohol Syndrome?
Rasheed A, Hines R, McCarver-May D. Variation in Induction of Human Placental CYP2E1: Possible Role in Susceptibility to Fetal Alcohol Syndrome? Toxicology And Applied Pharmacology 1997, 144: 396-400. PMID: 9194424, DOI: 10.1006/taap.1997.8152.Peer-Reviewed Original ResearchMeSH KeywordsAnthropometryCytochrome P-450 CYP2E1Disease SusceptibilityEnzyme InductionFemaleFetal Alcohol Spectrum DisordersHumansMicrosomes, LiverPlacentaPregnancyConceptsFetal alcohol syndromeAlcohol syndromeIntersubject variationHeavy drinking womenSmall birth weightAbsolute alcohol intakeWestern blot analysisBirth lengthAlcohol intakeDrinking womenHepatic CYP2E1Birth weightTerm placentaHeavy drinkersAlcohol metabolismCYP2E1Placental microsomesHuman placentaHeavy drinkingPlacentaTime pointsPotential mechanismsEnvironmental agentsWomenPregnancy