2007
Mechanisms Regulating Human FMO3 Transcription
Klick D, Hines R. Mechanisms Regulating Human FMO3 Transcription. Drug Metabolism Reviews 2007, 39: 419-442. PMID: 17786630, DOI: 10.1080/03602530701498612.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCells, CulturedData Interpretation, StatisticalElectrophoretic Mobility Shift AssayFemaleFetusGene Expression Regulation, EnzymologicHumansLiverLuciferasesMaleMiddle AgedMutagenesis, Site-DirectedOxygenasesPlasmidsPregnancyConceptsGC-box binding proteinsHepG2 cellsPromoter characterizationLiver nuclear proteinsNuclear proteinsTransient expressionFMO enzymesDevelopmental expressionBinding proteinTranscriptionAdult regulationProteinSpecific mechanismsEnzymeExpressionCellsNFYMajor roleYY1USF1Oxidative drugsHeterodimersMonooxygenasesReporterIsoforms
2004
Two distinct classes of CCAAT box elements that bind nuclear factor-Y/α-actinin-4: potential role in human CYP1A1 regulation
Poch M, Al-Kassim L, Smolinski S, Hines R. Two distinct classes of CCAAT box elements that bind nuclear factor-Y/α-actinin-4: potential role in human CYP1A1 regulation. Toxicology And Applied Pharmacology 2004, 199: 239-250. PMID: 15364540, DOI: 10.1016/j.taap.2003.12.023.Peer-Reviewed Original ResearchMeSH KeywordsActininBlotting, SouthwesternCCAAT-Binding FactorChromatinCytochrome P-450 CYP1A1Electrophoresis, Polyacrylamide GelElectrophoretic Mobility Shift AssayEnzyme InhibitorsGene Expression Regulation, EnzymologicHeLa CellsHumansPhosphatidylinositol 3-KinasesPhosphoinositide-3 Kinase InhibitorsPrecipitin TestsProtein BindingTranscription Factors