1989
Glucocorticoid regulation of the rat cytochrome P450c (P450IA1) gene: Receptor binding within intron I
Mathis J, Houser W, Bresnick E, Cidlowski J, Hines R, Prough R, Simpson E. Glucocorticoid regulation of the rat cytochrome P450c (P450IA1) gene: Receptor binding within intron I. Archives Of Biochemistry And Biophysics 1989, 269: 93-105. PMID: 2916850, DOI: 10.1016/0003-9861(89)90090-8.Peer-Reviewed Original ResearchConceptsGlucocorticoid receptorConcentrations of dexamethasoneUntreated cellsMRNA contentFetal rat hepatocytesHalf-maximal increaseAddition of dexamethasonePresence of dexamethasoneCultured fetal rat hepatocytesGlucocorticoid-responsive elementRat hepatocytesDexamethasoneCytochrome P450cGlucocorticoid regulationHepG2 hepatoma cellsGlucocorticoidsAcetyltransferase activityHepatic cytochromeChloramphenicol acetyltransferase activityReceptorsNorthern blot analysisBlot analysisHepatoma cellsReceptor fraction
1986
Regulation of cytochrome P-450c by glucocorticoids and polycyclic aromatic hydrocarbons in cultured fetal rat hepatocytes
Mathis J, Prough R, Hines R, Bresnick E, Simpson E. Regulation of cytochrome P-450c by glucocorticoids and polycyclic aromatic hydrocarbons in cultured fetal rat hepatocytes. Archives Of Biochemistry And Biophysics 1986, 246: 439-448. PMID: 2870681, DOI: 10.1016/0003-9861(86)90490-x.Peer-Reviewed Original Research