3-Methylcholanthrene-induced expression of the cytochrome P-450c gene
Foldes R, Hines R, Ho K, Shen M, Nagel K, Bresnick E. 3-Methylcholanthrene-induced expression of the cytochrome P-450c gene. Archives Of Biochemistry And Biophysics 1985, 239: 137-146. PMID: 4004253, DOI: 10.1016/0003-9861(85)90820-3.Peer-Reviewed Original ResearchConceptsNuclear RNA speciesCytochrome P-450c mRNARNA speciesCytochrome P-450c geneP-450c geneClone 46Nuclear transcription systemNuclear RNA precursorsNuclear RNA transportRat serum albumin geneDot hybridization experimentsSerum albumin geneNorthern blot analysisTranscriptional controlRNA transportRNA precursorsNuclear RNARegulation of inductionHybridization experimentsTranscription systemM13 subclonesAlbumin geneCytochrome P-450cRNA inductionSpeciesGene structure and nucleotide sequence for rat cytochrome P-450c
Hines R, Levy J, Conrad R, Iversen P, Shen M, Renli A, Bresnick E. Gene structure and nucleotide sequence for rat cytochrome P-450c. Archives Of Biochemistry And Biophysics 1985, 237: 465-476. PMID: 3838427, DOI: 10.1016/0003-9861(85)90300-5.Peer-Reviewed Original ResearchConceptsRat cytochrome P-450cRegulatory sequencesCDNA sequenceEntire geneSecond genomic cloneCommon ancestral geneGenomic blot analysisComplete cDNA sequenceIntron/exon junctionsPotential regulatory sequencesCytochrome P-450c mRNACytochrome P-450c genePartial cDNA cloneRat genomic libraryAmino acid sequenceCross-hybridization studiesGross structural differencesA fragmentGT/AGExon 2P-450c geneAncestral geneGene structureGenomic clonesCytochrome P3-450