2016
Age-Dependent Human Hepatic Carboxylesterase 1 (CES1) and Carboxylesterase 2 (CES2) Postnatal Ontogeny
Hines R, Simpson P, McCarver D. Age-Dependent Human Hepatic Carboxylesterase 1 (CES1) and Carboxylesterase 2 (CES2) Postnatal Ontogeny. Drug Metabolism And Disposition 2016, 44: 959-966. PMID: 26825642, DOI: 10.1124/dmd.115.068957.Peer-Reviewed Original ResearchConceptsHepatic carboxylesterase 1Weeks of ageCarboxylesterase 1CES2 expressionAge groupsYounger age groupsCES1 expressionLiver diseaseAdverse outcomesMetabolic clearancePmol/Older groupOlder individualsWestern blottingLiver samplesWeeksEnvironmental chemicalsPostnatal ontogenyMicrosomal proteinMedian valueAgeCytosolic fractionGroupExpressionSubjects
2012
Amine Oxidases and Reductases
Hines R, Prough R. Amine Oxidases and Reductases. 2012, 1-27. DOI: 10.1002/9780470921920.edm012.Peer-Reviewed Original ResearchNatural environmental chemicalsCytochrome P450-dependent monooxygenasesP450-dependent monooxygenasesAmine oxidationVariety of compoundsParticular reactionAmine oxidaseEnvironmental chemicalsEnzymeGenesMonooxygenasesProteinReductaseEndogenous aminesVariety of drugsOxidationAminesCompoundsOxidaseReactionChemicalsVariety