2007
Mechanisms Regulating Human FMO3 Transcription
Klick D, Hines R. Mechanisms Regulating Human FMO3 Transcription. Drug Metabolism Reviews 2007, 39: 419-442. PMID: 17786630, DOI: 10.1080/03602530701498612.Peer-Reviewed Original ResearchConceptsGC-box binding proteinsHepG2 cellsPromoter characterizationLiver nuclear proteinsNuclear proteinsTransient expressionFMO enzymesDevelopmental expressionBinding proteinTranscriptionAdult regulationProteinSpecific mechanismsEnzymeExpressionCellsNFYMajor roleYY1USF1Oxidative drugsHeterodimersMonooxygenasesReporterIsoforms
1994
Restoration of aryl hydrocarbon (Ah) responsiveness in MDA-MB-231 human breast cancer cells by transient expression of the estrogen receptor
Thomsen J, Wang X, Hines R, Safe S. Restoration of aryl hydrocarbon (Ah) responsiveness in MDA-MB-231 human breast cancer cells by transient expression of the estrogen receptor. Carcinogenesis 1994, 15: 933-937. PMID: 8200098, DOI: 10.1093/carcin/15.5.933.Peer-Reviewed Original ResearchConceptsMDA-MB-231 cellsHuman breast cancer cellsMDA-MB-231 human breast cancer cellsAh-responsivenessBreast cancer cellsNM TCDDHuman estrogen receptor expression plasmidAryl hydrocarbon responsivenessCancer cellsReceptor expression plasmidAryl hydrocarbon receptorProgesterone receptorEstrogen receptorResponsive plasmidCYP1A1 gene expressionHydrocarbon receptorReceptorsCell linesCYP1A1 geneCAT activityExpression of nuclearParallel studyHuman CYP1A1 geneCellsExpression plasmid
1988
Production of growth factors related to fibroblast growth factor and platelet-derived growth factor by human embryonal carcinoma cells
Tiesman J, Meyer A, Hines R, Rizzino A. Production of growth factors related to fibroblast growth factor and platelet-derived growth factor by human embryonal carcinoma cells. In Vitro Cellular & Developmental Biology 1988, 24: 1209-1216. PMID: 3209587, DOI: 10.1007/bf02624192.Peer-Reviewed Original ResearchConceptsPlatelet-derived growth factorGrowth factorSK-Hep-1 cellsEC cellsMouse EC cellsCarcinoma cellsHuman EC cell linesNT2/D1Basic fibroblast growth factorGrowth factor productionHeparin-binding growth factorsEmbryonal carcinoma cellsEC cell linesPDGF A-chainFibroblast growth factorHuman embryonal carcinoma cellsHuman EC cellsMouse embryonal carcinoma cellsFactor productionFGFbCell linesCDNA probeSimilar salt concentrationsCellsCurrent study