1989
Altered Regulation of the Cytochrome P4501A1 Gene: Novel Inducer-Independent Gene Expression in Pulmonary Carcinoma Cell Lines
McLemore T, Adelberg S, Czerwinski M, Hubbard W, Yu S, Storeng R, Wood T, Hines R, Boyd M. Altered Regulation of the Cytochrome P4501A1 Gene: Novel Inducer-Independent Gene Expression in Pulmonary Carcinoma Cell Lines. Journal Of The National Cancer Institute 1989, 81: 1787-1794. PMID: 2555530, DOI: 10.1093/jnci/81.23.1787.Peer-Reviewed Original ResearchConceptsPulmonary carcinoma cell linesLung cancer cell linesCarcinoma cell linesCancer cell linesLung cancerCell linesCYP1A1 gene expressionNon-small cell linesSmall cell lung carcinomaHuman lung cancer cell linesHeavy cigarette smokersHuman pulmonary carcinoma cell linesNon-small cell lung carcinoma cell lineSmall cell lung cancer linesNon-small cellCell lung carcinomaNormal human lungCell lung cancer linesHuman lung cancerCYP1A1 mRNACell lung carcinoma cell lineLung cancer cellsAryl hydrocarbon hydroxylase activityCYP1A1 geneLung carcinoma cell line
1987
Aflatoxin B1-4-hydroxylase is associated with cytochrome P3-450 in C57BL6 mouse liver
Koser P, Faletto M, Bansal S, Caballes L, Bresnick E, Hines R, Gurtoo H. Aflatoxin B1-4-hydroxylase is associated with cytochrome P3-450 in C57BL6 mouse liver. Biochemical And Biophysical Research Communications 1987, 142: 872-878. PMID: 3103616, DOI: 10.1016/0006-291x(87)91494-x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAroclorsAryl Hydrocarbon HydroxylasesBenzoflavonesBeta-NaphthoflavoneChlorodiphenyl (54% Chlorine)Cytochrome P-450 Enzyme SystemDNAEnzyme InductionFemaleLiverMethylcholanthreneMiceMice, Inbred C57BLMixed Function OxygenasesNucleic Acid HybridizationPolychlorinated BiphenylsRNA, MessengerConceptsHigh dosesLow doseP1-450Aryl hydrocarbon hydroxylase activityP3-450 mRNAHydroxylase activityMouse liverDosesP3-450Aroclor 1254MiceLiverDoseMessenger RNACytochrome P3-450MRNA