2023
Interactive association of posttraumatic stress disorder, apolipoprotein ε4 genotype, and age on cognitive functioning
Lawrence K, Rippey C, Welikson B, Pietrzak R, Adams T. Interactive association of posttraumatic stress disorder, apolipoprotein ε4 genotype, and age on cognitive functioning. International Journal Of Geriatric Psychiatry 2023, 38: e5888. PMID: 36757293, PMCID: PMC10168127, DOI: 10.1002/gps.5888.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderThree-way interactionCognitive functioningStress disorderOlder participantsTreatment of PTSDMain effectProbable posttraumatic stress disorderAge-related cognitive impairmentAPOE ε4U.S. military veteransApolipoprotein ε4 genotypeCognitive deficitsPsychomotor performanceAge-related associationsInteractive associationsVeterans StudyMilitary veteransCognitive impairmentPreliminary evidenceTwo-way interactionAPM performanceΕ4 carriersAnalysis of covarianceFunctioning
2020
Positive Age Beliefs Lead to Lower Dementia Risk Even Among Older Persons With High-Risk Gene
Levy B, Slade M, Pietrzak R, Ferrucci L. Positive Age Beliefs Lead to Lower Dementia Risk Even Among Older Persons With High-Risk Gene. Innovation In Aging 2020, 4: 597-597. PMCID: PMC7742059, DOI: 10.1093/geroni/igaa057.2009.Peer-Reviewed Original ResearchOlder individualsLower dementia riskStrong risk factorRetirement Study participantsHigh-risk genesΕ4 variantDementia riskRisk factorsΕ4 carriersAPOE ε4High riskDementiaOlder personsStudy participantsAPOE geneProtective factorsRelevant covariatesRiskTotal sampleBaselineCurrent studyCohortΕ4Individuals