1985
Neurologic, neuropsychologic, and computed cranial tomography scan abnormalities in 2- to 10-year survivors of small-cell lung cancer.
Johnson B, Becker B, Goff W, Petronas N, Krehbiel M, Makuch R, McKenna G, Glatstein E, Ihde D. Neurologic, neuropsychologic, and computed cranial tomography scan abnormalities in 2- to 10-year survivors of small-cell lung cancer. Journal Of Clinical Oncology 1985, 3: 1659-67. PMID: 2999346, DOI: 10.1200/jco.1985.3.12.1659.Peer-Reviewed Original ResearchConceptsProphylactic cranial irradiationMental status examinationLarge radiotherapy fractionsCranial irradiationStatus ExaminationScan abnormalitiesNeuropsychologic testingSmall-cell lung cancer trialHigh-dose induction chemotherapyLow-dose maintenance chemotherapySmall cell lung cancerRadiotherapy fractionsAbnormal neurologic examinationCranial tomography scanProgressive ventricular dilatationTherapeutic cranial irradiationTomography scan abnormalitiesHigh-dose chemotherapyStart of therapyLong-term survivorsLung cancer trialsMajority of casesCCT findingsInduction chemotherapyMaintenance chemotherapy
1984
A comparison of computed tomography and radionuclide scanning for detection of brain metastases in small cell lung cancer.
Crane J, Nelson M, Ihde D, Makuch R, Glatstein E, Zabell A, Johnston-Early A, Bates H, Saini N, Cohen M. A comparison of computed tomography and radionuclide scanning for detection of brain metastases in small cell lung cancer. Journal Of Clinical Oncology 1984, 2: 1017-24. PMID: 6088707, DOI: 10.1200/jco.1984.2.9.1017.Peer-Reviewed Original ResearchConceptsSmall cell lung cancerRadionuclide brain scanCell lung cancerBrain metastasesCT scanBrain scansAsymptomatic patientsNeurologic signsLung cancerExtensive-stage diseaseTherapeutic cranial irradiationTomographic brain scansCT brain scanSix-month intervalsCranial irradiationRN scansSCLC patientsAsymptomatic lesionsSymptomatic patientsSystemic therapyConsecutive patientsNeurologic historyComputed tomographyPatientsMetastasisDiagnosis and significance of liver metastases in small cell carcinoma of the lung.
Mulshine J, Makuch R, Johnston-Early A, Matthews M, Carney D, Ihde D, Cohen M, Bates H, Dunnick N, Minna J. Diagnosis and significance of liver metastases in small cell carcinoma of the lung. Journal Of Clinical Oncology 1984, 2: 733-41. PMID: 6330314, DOI: 10.1200/jco.1984.2.7.733.Peer-Reviewed Original ResearchConceptsLiver function testsLiver metastasesLiver biopsyLiver scanFunction testsLiver evaluationSmall cell lung cancerNoninvasive procedureDisease-free survivorsPercutaneous liver biopsySmall cell carcinomaCell lung cancerRadionuclide liver scanResponse of patientsNational Cancer InstituteSuch metastasesLiver involvementConsecutive patientsStaging procedureHepatic metastasesPrognostic implicationsCell carcinomaPhysical examinationLung cancerCancer Institute