2017
Parasite MIF Orthologs
Holowka T, Bucala R. Parasite MIF Orthologs. Progress In Inflammation Research 2017, 221-239. DOI: 10.1007/978-3-319-52354-5_14.Peer-Reviewed Original ResearchMacrophage migration inhibitory factorHuman macrophage migration inhibitory factorImmune responseMIF receptor CD74Adaptive immune responsesMigration inhibitory factorPro-inflammatory activityAnimal model studiesInflammatory cytokinesReceptor CD74IL-8Novel treatmentsSmall molecule inhibitorsTherapeutic interventionsInhibitory factorInfectious diseasesMacrophage migrationHost macrophagesMIF orthologsPathogenic impactMolecule inhibitorsTautomerase activitySignal transduction pathwaysTransduction pathwaysNematode parasites
2010
AV411 (Ibudilast) and AV1013 are non-competitive inhibitors of macrophage migration inhibitory factor: a novel induced-fit allosteric inhibition mechanism (133.11)
Cho Y, Crichlow G, Vermeire J, Leng L, Du X, Hodsdon M, Bucala R, Cappello M, Gross M, Gaeta F, Johnson K, Lolis E. AV411 (Ibudilast) and AV1013 are non-competitive inhibitors of macrophage migration inhibitory factor: a novel induced-fit allosteric inhibition mechanism (133.11). The Journal Of Immunology 2010, 184: 133.11-133.11. DOI: 10.4049/jimmunol.184.supp.133.11.Peer-Reviewed Original ResearchMacrophage migration inhibitory factorMigration inhibitory factorInhibitory factorPro-inflammatory proteinsAnti-inflammatory activityAnti-inflammatory drugsNon-selective inhibitorPDE inhibitor rolipramNeuropathic painOpioid withdrawalBronchial asthmaOcular indicationsGlial cellsNon-competitive inhibitorPossible therapeuticsInhibitor rolipramChemotactic functionAV411Tautomerase activityInhibitorsAllosteric binding siteIsobutylmethylxanthineTreatmentAsthmaPain
2000
ChemInform Abstract: Inhibition of Macrophage Migration Inhibitory Factor (MIF) Tautomerase Activity by Dopachrome Analogues
Zhang X, Bucala R. ChemInform Abstract: Inhibition of Macrophage Migration Inhibitory Factor (MIF) Tautomerase Activity by Dopachrome Analogues. ChemInform 2000, 31: no-no. DOI: 10.1002/chin.200008138.Peer-Reviewed Original Research
1999
Inhibition of macrophage migration inhibitory factor (MIF) tautomerase activity by dopachrome analogs
Zhang X, Bucala R. Inhibition of macrophage migration inhibitory factor (MIF) tautomerase activity by dopachrome analogs. Bioorganic & Medicinal Chemistry Letters 1999, 9: 3193-3198. PMID: 10576686, DOI: 10.1016/s0960-894x(99)00561-2.Peer-Reviewed Original Research