2016
Genetic polymorphisms of PPAR gamma, arsenic methylation capacity and breast cancer risk in Mexican women
Pineda-Belmontes CP, Hernández-Ramírez RU, Hernández-Alcaraz C, Cebrián ME, López-Carrillo L. Genetic polymorphisms of PPAR gamma, arsenic methylation capacity and breast cancer risk in Mexican women. Salud Pública De México 2016, 58: 220-227. PMID: 27557380, DOI: 10.21149/spm.v58i2.7791.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedArsenicArsenicalsBreast NeoplasmsCarrier ProteinsCase-Control StudiesChromatography, High Pressure LiquidEnvironmental ExposureFemaleGenetic Predisposition to DiseaseHumansMass SpectrometryMethylationMiddle AgedPolymerase Chain ReactionPolymorphism, Single NucleotidePPAR gammaRiskRNA-Binding ProteinsYoung AdultConceptsRisk of BCBreast cancerArsenic methylation capacityPolymerase chain reactionMethylation capacityMexican womenBreast cancer riskUrinary arsenic speciesCancer riskPresence of polymorphismsPPAR gammaPolymorphisms of interestUrine samplesGenetic polymorphismsChain reactionWomenHigh-performance liquid chromatographyRiskPolymorphismMethylation ratioSignificant interactionAssociationLiquid chromatography
2014
Arsenic methylation capacity is associated with breast cancer in northern Mexico
López-Carrillo L, Hernández-Ramírez RU, Gandolfi AJ, Ornelas-Aguirre JM, Torres-Sánchez L, Cebrian ME. Arsenic methylation capacity is associated with breast cancer in northern Mexico. Toxicology And Applied Pharmacology 2014, 280: 53-59. PMID: 25062773, DOI: 10.1016/j.taap.2014.07.013.Peer-Reviewed Original ResearchConceptsPrimary methylation indexBC riskSecondary methylation indexHospital-based case-control studyMethylation indexMethylation capacityHigher BC riskBreast cancer incidenceCase-control studyRisk of BCBiological exposure indexArsenic methylation capacityMetabolite percentagesDietary factorsCancer incidenceBreast cancerIAs metabolismMost womenTotal urinaryReproductive historyBC carcinogenesisInter-individual variationWomenExposure indexRisk
2011
Phthalate exposure associated with self-reported diabetes among Mexican women
Svensson K, Hernández-Ramírez RU, Burguete-García A, Cebrián ME, Calafat AM, Needham LL, Claudio L, López-Carrillo L. Phthalate exposure associated with self-reported diabetes among Mexican women. Environmental Research 2011, 111: 792-796. PMID: 21696718, PMCID: PMC5240471, DOI: 10.1016/j.envres.2011.05.015.Peer-Reviewed Original ResearchConceptsSelf-reported diabetesPhthalate exposureMexican womenExploratory cross-sectional studyCase-control studyCross-sectional studyGenesis of diabetesUbiquitous industrial chemicalsAdult Mexican womenAdverse health effectsDiabetes statusHealthy womenSignificant positive associationPhthalate metabolitesUrinary concentrationsBreast cancerImportant confoundersMonobenzyl phthalateDiabetesPlace of residencePossible associationMetabolic homeostasisHealth effectsWomenDilution tandem mass spectrometryPersonal care product use and urinary levels of phthalate metabolites in Mexican women
Romero-Franco M, Hernández-Ramírez RU, Calafat AM, Cebrián ME, Needham LL, Teitelbaum S, Wolff MS, López-Carrillo L. Personal care product use and urinary levels of phthalate metabolites in Mexican women. Environment International 2011, 37: 867-871. PMID: 21429583, DOI: 10.1016/j.envint.2011.02.014.Peer-Reviewed Original ResearchConceptsMono-3-carboxypropyl phthalateMono-n-butyl phthalateMono-2-ethylhexyl phthalatePhthalate metabolitesUrinary concentrationsMonoethyl phthalateUrinary levelsPopulation-based case-control studyOngoing population-based case-control studyPersonal care product useMono-isobutyl phthalateHigh-performance liquid chromatography isotope-dilution tandem mass spectrometryCase-control studyDetectable urinary concentrationsCarboxypentyl phthalateHydroxyhexyl phthalateOxohexyl phthalateBreast cancerLiquid chromatography-isotope dilution tandem mass spectrometryMonobenzyl phthalateReproductive historySociodemographic characteristicsGenetic susceptibilityPotential health impactsMexican women
2009
Exposure to Phthalates and Breast Cancer Risk in Northern Mexico
López-Carrillo L, Hernández-Ramírez RU, Calafat AM, Torres-Sánchez L, Galván-Portillo M, Needham LL, Ruiz-Ramos R, Cebrián ME. Exposure to Phthalates and Breast Cancer Risk in Northern Mexico. Environmental Health Perspectives 2009, 118: 539-544. PMID: 20368132, PMCID: PMC2854732, DOI: 10.1289/ehp.0901091.Peer-Reviewed Original ResearchConceptsBreast cancerMonoethyl phthalatePhthalate metabolitesUrinary concentrationsRisk of BCMono-n-butyl phthalateBreast cancer riskGeometric mean concentrationsPremenopausal womenRisk factorsParent phthalatesCancer riskMonobenzyl phthalateBC casesSignificant negative associationEndocrine systemMexican womenUrine samplesUbiquitous environmental pollutantWomenHigh-performance liquid chromatographyAssociationNegative associationExposureMCPP