2018
PCORnet Antibiotics and Childhood Growth Study: Process for Cohort Creation and Cohort Description
Block J, Bailey L, Gillman M, Lunsford D, Boone-Heinonen J, Cleveland L, Finkelstein J, Horgan C, Jay M, Reynolds J, Sturtevant J, Forrest C, Group P, Adams W, Appelhans B, Brickman A, Bian J, Daley M, Davidson A, Dempsey A, Dugas L, Eneli I, Fitzpatrick S, Heerman W, Horberg M, Hsia D, Ingber J, Isasi C, Janicke D, Kane D, Kharbanda E, Meltzer D, Messito M, Nadkarni P, O'Bryan K, Peay H, Puro J, Ranade D, Rao G, Tirado-Ramos A, Rayas M, Razzaghi H, Ricket I, Rosenman M, Siegel R, Solomonides T, Taveras E, Taylor B, Tolia V, Willis Z, VanWormer J, Wysocki T, Zhou X. PCORnet Antibiotics and Childhood Growth Study: Process for Cohort Creation and Cohort Description. Academic Pediatrics 2018, 18: 569-576. PMID: 29477481, PMCID: PMC9746871, DOI: 10.1016/j.acap.2018.02.008.Peer-Reviewed Original ResearchConceptsAntibiotic prescriptionsAntibiotic useObservational studySex-specific body mass indexCohort inclusion criteriaEarly antibiotic useSame-day heightSingle antibiotic prescriptionsBody mass indexLongitudinal observational studyClinical Research NetworkBroad-spectrum antibioticsMonths of agePCORnet common data modelCohort creationSevere obesityNational PatientMass indexCohort descriptionObesity prevalenceInclusion criteriaCohort characteristicsHealth care dataCare dataClinical research
2016
Quality of EHR data extractions for studies of preterm birth in a tertiary care center: guidelines for obtaining reliable data
Knake L, Ahuja M, McDonald E, Ryckman K, Weathers N, Burstain T, Dagle J, Murray J, Nadkarni P. Quality of EHR data extractions for studies of preterm birth in a tertiary care center: guidelines for obtaining reliable data. BMC Pediatrics 2016, 16: 59. PMID: 27130217, PMCID: PMC4851819, DOI: 10.1186/s12887-016-0592-z.Peer-Reviewed Original ResearchConceptsEHR data extractionElectronic health recordsWhite blood cell countTertiary care centerData extractionBlood cell countInitial hemoglobinNeonatal recordsChart reviewFuture study designsPreterm birthChart extractionGestational ageOutside hospitalManual data abstractionBirth weightCare centerDirect bilirubinLaboratory valuesCell countBirth dataStudy designHealth recordsManual abstractionGuidelines
2013
Radiation exposure and breast cancer: lessons from Chernobyl.
Ogrodnik A, Hudon T, Nadkarni P, Chandawarkar R. Radiation exposure and breast cancer: lessons from Chernobyl. Connecticut Medicine 2013, 77: 227-34. PMID: 23691737.Peer-Reviewed Original Research
2011
Pretraining and Posttraining Assessment of Residents' Performance in the Fourth Accreditation Council for Graduate Medical Education Competency: Patient Communication Skills
Chandawarkar RY, Ruscher KA, Krajewski A, Garg M, Pfeiffer C, Singh R, Longo WE, Kozol RA, Lesnikoski B, Nadkarni P. Pretraining and Posttraining Assessment of Residents' Performance in the Fourth Accreditation Council for Graduate Medical Education Competency: Patient Communication Skills. JAMA Surgery 2011, 146: 916-921. PMID: 21844435, DOI: 10.1001/archsurg.2011.167.Peer-Reviewed Original ResearchConceptsPatient communication skillsStandardized patient instructorsCancer scoreRating Scale scoresBreast cancer scoreMaster Interview Rating ScalePatient instructorsResidents' communication skillsInstitutional review boardGeneral surgery residentsMimic patientsRectal cancerProspective studyScale scoreSurgical residents' abilityPatient communicationMedian scoreCommunication skillsReview boardBaseline surveyRating ScaleGeneral communication skillsSurgery residentsGraduate Medical Education competenciesRank test
2003
The Cancer Genetics Network: Recruitment Results and Pilot Studies
Anton-Culver H, Ziogas A, Bowen D, Finkelstein D, Griffin C, Hanson J, Isaacs C, Kasten-Sportes C, Mineau G, Nadkarni P, Rimer B, Schildkraut J, Strong L, Weber B, Winn D, Hiatt R, Nayfield S. The Cancer Genetics Network: Recruitment Results and Pilot Studies. Public Health Genomics 2003, 6: 171-177. PMID: 15237201, DOI: 10.1159/000078165.Peer-Reviewed Original ResearchConceptsCancer Genetics NetworkFirst-degree relativesNational Cancer InstitutePublic health issuePotential study participantsFamily membersDifferent study designsCancer patientsCancer InstituteStudy participantsGenetic susceptibilityEstablishment of guidelinesStandard questionnaireStudy designPilot studyHealth issuesCancer susceptibilityTranslational researchPatientsResearch protocolCancer Genetics StudyFamily studiesMedical practiceRecruitment resultsMultiple ethnicities
2000
Using a Computer Database to Monitor Compliance With Pharmacotherapeutic Guidelines for Schizophrenia
Chen RS, Nadkarni PM, Levin FL, Miller PL, Erdos J, Rosenheck RA. Using a Computer Database to Monitor Compliance With Pharmacotherapeutic Guidelines for Schizophrenia. Psychiatric Services 2000, 51: 791-794. PMID: 10828112, DOI: 10.1176/appi.ps.51.6.791.Peer-Reviewed Original ResearchConceptsPatient Outcomes Research TeamAcute episodePrescription dataSchizophrenia Patient Outcomes Research TeamVeterans Affairs Medical CenterTrial of clozapinePercent of patientsFirst-line treatmentPatient prescription dataPharmacotherapeutic guidelinesPharmacotherapeutic recommendationsAdequate trialConventional antipsychoticsConventional medicationsConventional regimensOutpatient visitsAntipsychotic regimenTreatment recommendationsSymptom episodesMedical CenterPatientsClozapineConventional drugsComputerized databasePORT recommendations
1992
Fast Computation of Genetic Likelihoods on Human Pedigree Data
Goradia T, Lange K, Miller P, Nadkarni P. Fast Computation of Genetic Likelihoods on Human Pedigree Data. Human Heredity 1992, 42: 42-62. PMID: 1555846, DOI: 10.1159/000154045.Peer-Reviewed Original ResearchConceptsHuman pedigree dataNetwork of workstationsLarge-scale computationsHardware techniquesParallel machinesComputational speedDifferent architecturesLinkage problemFast computationVectorized versionComputationFast calculationLarge numberParallelizationSupercomputersVectorizationComplete phenotypingWorkstationsArchitectureGenetic likelihoodMachineNetworkVersionNew methodSubstantial improvement