2011
Web-browser encryption of personal health information
Morse R, Nadkarni P, Schoenfeld D, Finkelstein D. Web-browser encryption of personal health information. BMC Medical Informatics And Decision Making 2011, 11: 70. PMID: 22073940, PMCID: PMC3276430, DOI: 10.1186/1472-6947-11-70.Peer-Reviewed Original ResearchConceptsPersonal health informationRemote data entryWeb browserSensitive informationData centersHealth informationData entryHealth recordsUnprecedented amountPatient dataPatient confidentialityFinancial lossesClinical dataInformationMedical conditionsEncryptionServerBrowserClinical researchEffective medical practiceRange of situationsConfidentialityAccessSystemMedical practice
2009
Automated Database Mediation Using Ontological Metadata Mappings
Marenco L, Wang R, Nadkarni P. Automated Database Mediation Using Ontological Metadata Mappings. Journal Of The American Medical Informatics Association 2009, 16: 723-737. PMID: 19567801, PMCID: PMC2744723, DOI: 10.1197/jamia.m3031.Peer-Reviewed Original ResearchConceptsCross-database queriesHigh-level rulesEnforcement of constraintsDatabase MediationDatabase federationsDatabase ontologyExtended metadataGranularity levelsMetadata mappingBiomedical ontologiesDifferent granularitiesFramework simplifiesCategories of dataMaintenance of systemsMapping rulesQueriesDatabase informationGranularity of representationGlobal vocabularyOntologyGranularityIntegrator systemMetadataDatabaseSNOMED
2007
SenseLab: new developments in disseminating neuroscience information
Crasto CJ, Marenco LN, Liu N, Morse TM, Cheung KH, Lai PC, Bahl G, Masiar P, Lam HY, Lim E, Chen H, Nadkarni P, Migliore M, Miller PL, Shepherd GM. SenseLab: new developments in disseminating neuroscience information. Briefings In Bioinformatics 2007, 8: 150-162. PMID: 17510162, PMCID: PMC2756159, DOI: 10.1093/bib/bbm018.Peer-Reviewed Original Research
2005
Metadata-driven Delphi rating on the Internet
Deshpande AM, Shiffman RN, Nadkarni PM. Metadata-driven Delphi rating on the Internet. Computer Methods And Programs In Biomedicine 2005, 77: 49-56. PMID: 15639709, DOI: 10.1016/j.cmpb.2004.05.006.Peer-Reviewed Original ResearchConceptsDelphi ratingPaper-based data collectionTraditional paper-based methodsReusable softwarePaper-based methodsProgramming codeData entrySoftwareAnalysis toolsMetadataComputerized techniqueData collectionValues schemaInternetSchemaFive-level Likert scaleWebCodeDisagreement indexGuideline StandardizationExpertsToolMethodCostCollection
2004
Integration of Web-based and PC-based Clinical Research Databases
Brandt CA, Sun K, Charpentier P, Nadkarni PM. Integration of Web-based and PC-based Clinical Research Databases. Methods Of Information In Medicine 2004, 43: 287-295. PMID: 15227559, DOI: 10.1055/s-0038-1633870.Peer-Reviewed Original ResearchConceptsDatabase applicationsClinical study data management systemsIntegration of applicationsCommon semantic modelData management systemWeb-based repositoryClinical research databaseSchema conflictsSharing of featuresData managementMapping schemaSemantic modelDifferent operating environmentsModel unificationManagement systemIntegration effortsOperating environmentArea of applicabilityData collectionMajor benefitsSimilar purposesIntegrationApplicationsCritical conflictsData libraries
2003
Achieving Evolvable Web-Database Bioscience Applications Using the EAV/CR Framework: Recent Advances
Marenco L, Tosches N, Crasto C, Shepherd G, Miller PL, Nadkarni PM. Achieving Evolvable Web-Database Bioscience Applications Using the EAV/CR Framework: Recent Advances. Journal Of The American Medical Informatics Association 2003, 10: 444-453. PMID: 12807806, PMCID: PMC212781, DOI: 10.1197/jamia.m1303.Peer-Reviewed Original ResearchConceptsEAV/CRXML-based protocolHuman Brain ProjectDatabase supportData querySemantic descriptorsAutomatic generationNeuroscience databasesCR frameworkScientific domainsBrain ProjectInterclass relationshipsSchema maintenanceFrameworkBioscience applicationsResearch focusQueriesMetadataDatabaseUMLSUsersData extractionDifferent subsetsSchemaParticular research focusTrialDB: A web-based Clinical Study Data Management System.
Brandt CA, Deshpande AM, Lu C, Ananth G, Sun K, Gadagkar R, Morse R, Rodriguez C, Miller PL, Nadkarni PM. TrialDB: A web-based Clinical Study Data Management System. AMIA Annual Symposium Proceedings 2003, 2003: 794. PMID: 14728299, PMCID: PMC1480035.Peer-Reviewed Original ResearchConceptsClinical study data management systemsData management systemClass of softwareManagement systemPre-existing softwareWeb-based technologiesOpen source formDatabase engineClinical domainsSuch softwareData managementCentralized managementDifferent clinical domainsChallenging taskSuch systemsValue modelingSoftwareRequisite functionalityIntranetInternetDiverse typesSystemTaskDomainEngine
2002
Metadata-driven Ad Hoc Query of Patient Data
Deshpande AM, Brandt C, Nadkarni PM. Metadata-driven Ad Hoc Query of Patient Data. Journal Of The American Medical Informatics Association 2002, 9: 369-382. PMID: 12087118, PMCID: PMC346624, DOI: 10.1197/jamia.m1034.Peer-Reviewed Original ResearchConceptsClinical study data management systemsClinical patient record systemsQuery interfaceAd-Hoc QueriesData management systemWeb-based platformPatient record systemManagement systemClinical studiesRecord systemMetadataStandardized therapeutic interventionsUnderlying clinical conditionSystem operationNon-research settingsClinical parametersPatient managementClinical conditionsQueriesPortingTherapeutic interventionsInterfaceSystemPlatformAD
2001
Web-based UMLS concept retrieval by automatic text scanning: a comparison of two methods
Brandt C, Nadkarni P. Web-based UMLS concept retrieval by automatic text scanning: a comparison of two methods. Computer Methods And Programs In Biomedicine 2001, 64: 37-43. PMID: 11084231, DOI: 10.1016/s0169-2607(00)00092-4.Peer-Reviewed Original ResearchConceptsWeb applicationActive server pages (ASP) technologyAppropriate programming environmentApplication deliveryDatabase engineCode portabilityScripting environmentRelational databaseWeb developmentDevelopment environmentProgramming environmentConcept retrievalText scanningPage technologySuch functionalityRobust languageVendor implementationsRapid prototypingIdentical applicationsMedium of choiceEasy accessEnvironmentLispMaintainabilityApplications
2000
WebEAV
Nadkarni P, Brandt C, Marenco L. WebEAV. Journal Of The American Medical Informatics Association 2000, 7: 343-356. PMID: 10887163, PMCID: PMC61439, DOI: 10.1136/jamia.2000.0070343.Peer-Reviewed Original ResearchConceptsWeb development environmentWeb application developmentUser interface issuesClient-server technologyValue databaseWeb technologiesApplication developmentEntity attributesWeb developmentDevelopment environmentWeb interfaceGeneric frameworkInterface issuesComplex systemsFront endDatabaseTechnologyMetadataDevelopersSuitable examplesArchitectureTaskFeaturesFrameworkVehiclesIntegration of a hematopoietic progenitor cell program using the ACT/DB database system
Perrotta P, Nadkarni P. Integration of a hematopoietic progenitor cell program using the ACT/DB database system. Computer Methods And Programs In Biomedicine 2000, 61: 195-207. PMID: 10710182, DOI: 10.1016/s0169-2607(99)00038-3.Peer-Reviewed Original ResearchConceptsClient-server databaseComprehensive software systemSQL Server databaseDiverse data requirementsWeb-based technologiesData entry formsSoftware systemsServer databaseDatabase systemsInformation technologyMicrosoft AccessControl functionalityEntry formData requirementsTechnologyInternetDatabaseQuality assuranceOracleDeploymentSoftwareSystemFunctionalityRequirementsProcessingThe Yale Center for Medical Informatics: clinical, neuro- and genomic informatics.
Miller PL, Brandt C, Cheung K, Mattie M, Nadkarni P, Shiffman RN. The Yale Center for Medical Informatics: clinical, neuro- and genomic informatics. M.D. Computing 2000, 17: 29-32. PMID: 11014075.Peer-Reviewed Original Research
1999
Organization of Heterogeneous Scientific Data Using the EAV/CR Representation
Nadkarni P, Marenco L, Chen R, Skoufos E, Shepherd G, Miller P. Organization of Heterogeneous Scientific Data Using the EAV/CR Representation. Journal Of The American Medical Informatics Association 1999, 6: 478-493. PMID: 10579606, PMCID: PMC61391, DOI: 10.1136/jamia.1999.0060478.Peer-Reviewed Original ResearchConceptsEAV/CRHeterogeneous scientific dataPhysical database schemaStorage of dataInterobject relationshipsDatabase schemaHeterogeneous dataMedical domainComplex objectsScientific domainsClinical patient recordsSchemaBiomedical databasesRepresentationScientific dataPatient recordsSuch purposesDatabaseValue representationDomainObjectsParadigmDataOlfactory Receptor Database: a database of the largest eukaryotic gene family
Skoufos E, Healy M, Singer M, Nadkarni P, Miller P, Shepherd G. Olfactory Receptor Database: a database of the largest eukaryotic gene family. Nucleic Acids Research 1999, 27: 343-345. PMID: 9847223, PMCID: PMC148178, DOI: 10.1093/nar/27.1.343.Peer-Reviewed Original ResearchNeuronal database integration: the Senselab EAV data model.
Marenco L, Nadkarni P, Skoufos E, Shepherd G, Miller P. Neuronal database integration: the Senselab EAV data model. AMIA Annual Symposium Proceedings 1999, 102-6. PMID: 10566329, PMCID: PMC2232788.Peer-Reviewed Original Research