1991
Modulation of Neonatal Neutrophil Function by Pentoxifylline
Krause P, Maderazo E, Contrino J, Eisenfeld L, Herson V, Greca N, Bannon P, Kreutzer D. Modulation of Neonatal Neutrophil Function by Pentoxifylline. Pediatric Research 1991, 29: 123-127. PMID: 2014147, DOI: 10.1203/00006450-199102000-00002.Peer-Reviewed Original ResearchConceptsPMN functionNitroblue tetrazolium reductionImpaired PMN functionsNeonatal neutrophil functionTetrazolium reductionTreatment of infectionsPolymorphonuclear leukocyte chemotaxisF-actin contentDose-dependent effectPotential clinical useCertain disease processesSimilar dose-dependent responseDose-dependent responseNeutrophil functionNewborn infantsPMN activityPMN deformabilityPMN chemotaxisDisease processPentoxifyllineLeukocyte chemotaxisMethylxanthine pentoxifyllinePhagocytic activityNeonatesClinical use
1990
Longitudinal study of neutrophil adherence and motility
Eisenfeld L, Krause P, Herson V, Savidakis J, Bannon P, Maderazo E, Woronick C, Giuliano C, Banco L. Longitudinal study of neutrophil adherence and motility. The Journal Of Pediatrics 1990, 117: 926-929. PMID: 2246695, DOI: 10.1016/s0022-3476(05)80139-8.Peer-Reviewed Original Research
1989
Characterization of Nonmotile Neutrophil Subpopulations in Neonates and Adults
Krause P, Kreutzer D, Eisenfeld L, Herson V, Weisman S, Bannon P, Greca N. Characterization of Nonmotile Neutrophil Subpopulations in Neonates and Adults. Pediatric Research 1989, 25: 519-524. PMID: 2717268, DOI: 10.1203/00006450-198905000-00019.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntibodies, MonoclonalChemotaxis, LeukocyteFetal BloodHumansInfant, NewbornNeutrophilsPhagocytosisConceptsPMN subpopulationPolymorphonuclear leukocytesPMN motilityAdult polymorphonuclear leukocytesMost polymorphonuclear leukocytesMicropore filtersNeutrophil subpopulationsHomogeneous populationPhagocytic functionNeonatesChemotactic stimuliMAbsSubpopulationsAdultsPMN precursorsPresent studyHigh percentageMotilityCellsPrevious studiesPopulationLeukocytesAntibodies
1987
Host defense during pregnancy: Neutrophil chemotaxis and adherence
Krause P, Ingardia C, Pontius L, Malech H, LoBello T, Maderazo E. Host defense during pregnancy: Neutrophil chemotaxis and adherence. American Journal Of Obstetrics And Gynecology 1987, 157: 274-280. PMID: 3618673, DOI: 10.1016/s0002-9378(87)80150-3.Peer-Reviewed Original ResearchMeSH KeywordsCell AdhesionChemotaxis, LeukocyteFemaleHumansLabor, ObstetricNeutrophilsPostpartum PeriodPregnancyConceptsPolymorphonuclear leukocyte chemotaxisPregnant womenLeukocyte chemotaxisThird trimesterLeukocyte adherenceNonpregnant control subjectsIncidence of infectionMonths post partumPolymorphonuclear leukocyte adherenceNylon wool columnsMicropore filter assaysHumoral defectsFirst trimesterAutoimmune diseasesControl subjectsImmunologic functionPostpartum periodNeutrophil chemotaxisPregnancyWool columnsHost defensePost partumTrimesterNeutrophil motilityWomenThe Effect of Betamethasone on Neonatal Neutrophil Chemotaxis
Fuenfer M, Herson V, Raye J, Woronick C, Eisenfeld L, Ingardia C, Block C, Krause P. The Effect of Betamethasone on Neonatal Neutrophil Chemotaxis. Pediatric Research 1987, 22: 150-153. PMID: 3658539, DOI: 10.1203/00006450-198708000-00009.Peer-Reviewed Original ResearchMeSH KeywordsBacterial InfectionsBetamethasoneChemotaxis, LeukocyteFetal BloodHumansIn Vitro TechniquesInfant, NewbornNeutrophilsConceptsEffect of betamethasoneBacterial infectionsNewborn infantsPMN functionMaternal glucocorticoid administrationNeonatal PMN functionFetal lung maturationMigration of PMNRandom migrationConcentrations of betamethasonePMN random migrationSignificant clinical importanceBetamethasone administrationGlucocorticoid administrationPregnant womenLung maturationNeutrophil functionStandard doseCord bloodNeutrophil chemotaxisAntiinflammatory agentsClinical importanceImportant causeImmune systemBetamethasone
1986
Polymorphonuclear Leukocyte Adherence and Chemotaxis in Stressed and Healthy Neonates
Krause P, Herson V, Boutin-Lebowitz J, Eisenfeld L, Block C, LoBello T, Maderazo E. Polymorphonuclear Leukocyte Adherence and Chemotaxis in Stressed and Healthy Neonates. Pediatric Research 1986, 20: 296-300. PMID: 3703618, DOI: 10.1203/00006450-198604000-00004.Peer-Reviewed Original ResearchConceptsStressed neonatesHealthy neonatesPMN adherencePMN chemotaxisAcute lower respiratory illnessBacterial infectionsPolymorphonuclear neutrophil (PMN) adherenceLower respiratory illnessPolymorphonuclear leukocyte adherenceRespiratory illnessNeutrophil adherenceLeukocyte adherenceFurther impairmentNeonatesHealthy adultsImportant causeGreater riskInfectionChemotaxis assaysAdherenceAdultsIllnessChemotaxisSignificant improvementSusceptibility