2024
Efficacy and safety of implantable cardioverter-defibrillator implantation in the elderly—The I-70 Study: A randomized clinical trial
Singh S, Wininger M, Raitt M, Adabag S, Moore H, Rottman J, Scrymgeour A, Zhang J, Zheng K, Guarino P, Kyriakides T, Group I, Johnson G, Williams A, Beed A, MacMurdy K, Saavedra P. Efficacy and safety of implantable cardioverter-defibrillator implantation in the elderly—The I-70 Study: A randomized clinical trial. Heart Rhythm O2 2024, 5: 365-373. PMID: 38984364, PMCID: PMC11228113, DOI: 10.1016/j.hroo.2024.04.010.Peer-Reviewed Original ResearchImplantable cardioverter defibrillatorParticipant follow-upPatient treatment preferencesICD implantationFollow-upTarget sample sizeAll-cause hospitalizationsPrimary prevention ICD implantationMonths of follow-upImplantable cardioverter defibrillator therapySafety of implantable cardioverter defibrillatorsImplantable cardioverter defibrillator implantationOptimal medical therapyRate of sudden deathTreatment preferencesImplantable cardioverter defibrillator shocksSafety of ICD implantationConfidence intervalsStudy protocolMedical therapyParticipantsProlonging lifePatientsSudden deathCardioverter defibrillator
2010
Robot-Assisted Therapy for Long-Term Upper-Limb Impairment after Stroke
Lo AC, Guarino PD, Richards LG, Haselkorn JK, Wittenberg GF, Federman DG, Ringer RJ, Wagner TH, Krebs HI, Volpe BT, Bever CT, Bravata DM, Duncan PW, Corn BH, Maffucci AD, Nadeau SE, Conroy SS, Powell JM, Huang GD, Peduzzi P. Robot-Assisted Therapy for Long-Term Upper-Limb Impairment after Stroke. New England Journal Of Medicine 2010, 362: 1772-1783. PMID: 20400552, PMCID: PMC5592692, DOI: 10.1056/nejmoa0911341.Peer-Reviewed Original ResearchConceptsWolf Motor Function TestFugl-Meyer scoreUsual careMotor Function TestRobot-assisted therapyStroke Impact ScaleIntensive therapySecondary analysisFunction testsComparison therapyMotor functionImpact ScaleSerious adverse eventsFugl-Meyer AssessmentUpper limb deficitsLong-term deficitsSensorimotor recoveryAdverse eventsSecondary outcomesPrimary outcomeRehabilitative therapyPatientsLimb impairmentTherapyStroke