Molecular Characterisation of Chikungunya Virus Infections in Trinidad and Comparison of Clinical and Laboratory Features with Dengue and Other Acute Febrile Cases
Sahadeo N, Mohammed H, Allicock O, Auguste A, Widen S, Badal K, Pulchan K, Foster J, Weaver S, Carrington C. Molecular Characterisation of Chikungunya Virus Infections in Trinidad and Comparison of Clinical and Laboratory Features with Dengue and Other Acute Febrile Cases. PLOS Neglected Tropical Diseases 2015, 9: e0004199. PMID: 26580074, PMCID: PMC4651505, DOI: 10.1371/journal.pntd.0004199.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overChikungunya FeverChikungunya virusDengueDiagnosis, DifferentialFemaleFever of Unknown OriginGenotypeHumansMaleMiddle AgedMolecular Diagnostic TechniquesMolecular Sequence DataPhylogenyRNA, ViralSequence Analysis, DNASequence HomologyTrinidad and TobagoYoung AdultConceptsAcute undifferentiated febrile illnessChikungunya feverChikungunya virusCHIKV infectionDengue virusDengue feverRT-qPCRExact testLower white blood cell countWhite blood cell countPearson χ2Undifferentiated febrile illnessCharacteristics of patientsChikungunya virus infectionSymptoms of peopleBlood cell countComparison of ClinicalConfidence intervalsFisher's exact testT-testStudent's t-testMann-Whitney UFebrile illnessJoint painLaboratory features