2024
Characterization of sleep apnea among a sample of adults from Samoa
Heinsberg L, Pomer A, Cade B, Carlson J, Naseri T, Reupena M, Viali S, Weeks D, McGarvey S, Redline S, Hawley N. Characterization of sleep apnea among a sample of adults from Samoa. Sleep Epidemiology 2024, 4: 100099. DOI: 10.1016/j.sleepe.2024.100099.Peer-Reviewed Original ResearchApnea-hypopnea indexOxygen desaturation indexSleep apneaCharacteristics of sleep apneaSevere sleep apneaSleep apnea deviceObesity-risk alleleGeographic region of residenceType 2 diabetesInfluence sleep healthHypopnea indexDesaturation indexGlobal public health concernApneaHigher BMIRegion of residenceCircumference ratioMale sexMiddle-income countriesSample of adultsPublic health concernSamoan adultsBMISleep healthHealth concernAssociations between fasting glucose rate-of-change and the missense variant, rs373863828, in an adult Samoan cohort
Rivara A, Russell E, Carlson J, Pomer A, Naseri T, Reupena M, Manna S, Viali S, Minster R, Weeks D, DeLany J, Kershaw E, McGarvey S, Hawley N. Associations between fasting glucose rate-of-change and the missense variant, rs373863828, in an adult Samoan cohort. PLOS ONE 2024, 19: e0302643. PMID: 38829901, PMCID: PMC11146712, DOI: 10.1371/journal.pone.0302643.Peer-Reviewed Original ResearchConceptsType 2 diabetesAllele of rs373863828Body mass indexFasting glucoseAdult SamoansDevelopment of type 2 diabetesOdds of type 2 diabetesReduction of modifiable risk factorsRs373863828 genotypeAssociated with higher body mass indexType 2 diabetes developmentGlucose rate of changeMass indexHousehold asset scoreUrbanization of residenceHigher body mass indexRisk factorsModifiable risk factorsRate of changeBaseline variablesMultivariate linear regressionPhysical activityDiabetes preventionType 2 diabetes mellitusSmoking status
2023
Protocol: Implementation and evaluation of an adolescent-mediated intervention to improve glycemic control and diabetes self-management among Samoan adults
Hawley N, Rivara A, Naseri J, Faumuina K, Potoa’e-Solaita N, Iopu F, Faiai M, Naveno E, Tasele S, Lefale T, Lantini R, Carlson J, Rabin T, Semaia P, Mugadza P, Rosen R. Protocol: Implementation and evaluation of an adolescent-mediated intervention to improve glycemic control and diabetes self-management among Samoan adults. PLOS ONE 2023, 18: e0279084. PMID: 36795707, PMCID: PMC9934313, DOI: 10.1371/journal.pone.0279084.Peer-Reviewed Original ResearchConceptsGlycemic controlPrimary efficacy outcomeCardiovascular risk factorsChronic disease riskType 2 diabetesSelf-care strategiesSelf-care practicesHealth behavior changeBehavior changeEfficacy outcomesUsual careDiabetes InterventionsAdult family membersRisk factorsDiabetes knowledgeSamoan adultsIntervention acceptabilityFamily-centered culturePositive behavior changeDisease riskHealth disparitiesActive interventionDisproportionate riskInterventionEthnic minority groups
2022
Associations between diabetes-related symptoms, glycemic control, and health-related quality of life in adult Samoans
Rivara A, Pomer A, Wetzel A, Viali S, Naseri T, Reupena M, Kershaw E, McGarvey S, Hawley N. Associations between diabetes-related symptoms, glycemic control, and health-related quality of life in adult Samoans. Pacific Health Dialog 2022, 21: 638-655. DOI: 10.26635/phd.2022.142.Peer-Reviewed Original ResearchHealth-related qualityDiabetes-related symptomsGlycemic controlAdult SamoansSymptom presenceDiabetes self-care behaviorsSymptom checklist questionnairesHigh symptom burdenDiabetes-related complicationsMultivariate logistic regressionType 2 diabetesSelf-care behaviorsMann-Whitney U testEarly evaluationChi-square testSymptom burdenDiabetes statusCommon symptomsDiabetes symptomsWhitney U testHeart painSeries of anthropometricHigh prevalenceDiabetes experiencePrediabetesThe protective effect of rs373863828 on type 2 diabetes does not operate through a body composition pathway in adult Samoans
Hawley NL, Duckham RL, Carlson JC, Naseri T, Reupena MS, Lameko V, Pomer A, Wetzel A, Selu M, Lupematisila V, Unasa F, Vesi L, Fatu T, Unasa S, Faasalele‐Savusa K, Rivara AC, Russell E, Delany JP, Viali S, Kershaw EE, Minster RL, Weeks DE, McGarvey ST. The protective effect of rs373863828 on type 2 diabetes does not operate through a body composition pathway in adult Samoans. Obesity 2022, 30: 2468-2476. PMID: 36284436, PMCID: PMC10111239, DOI: 10.1002/oby.23559.Peer-Reviewed Original ResearchConceptsFat-free massType 2 diabetesFat distributionProtective effectBody compositionFavorable body fat distributionDual-energy X-ray absorptiometry-derived body compositionBody fat distributionGreater fat-free massPercent body fatBody size/compositionAssociation of genotypesRs373863828 genotypeVisceral adiposityHigher BMIAdult SamoansRole of fatGreater BMILean massBody fatLower oddsParadoxical associationTissue-specific mechanismsA alleleDiabetesCREBRF missense variant rs373863828 has both direct and indirect effects on type 2 diabetes and fasting glucose in Polynesian peoples living in Samoa and Aotearoa New Zealand
Russell EM, Carlson JC, Krishnan M, Hawley NL, Sun G, Cheng H, Naseri T, Reupena M, Viali S, Tuitele J, Major TJ, Miljkovic I, Merriman TR, Deka R, Weeks DE, McGarvey ST, Minster RL. CREBRF missense variant rs373863828 has both direct and indirect effects on type 2 diabetes and fasting glucose in Polynesian peoples living in Samoa and Aotearoa New Zealand. BMJ Open Diabetes Research & Care 2022, 10: e002275. PMID: 35144939, PMCID: PMC8845200, DOI: 10.1136/bmjdrc-2021-002275.Peer-Reviewed Original ResearchConceptsBody mass indexType 2 diabetesAssociation of BMIHigher body mass indexMinor alleleType 2 diabetes riskCross-sectional associationsPacific Island populationsRs373863828 genotypeMass indexDiabetes riskHigher oddsLower oddsDiabetesObesityEvidence of differencesMissense variantsRs373863828Regression analysisGlucoseAssociationOddsIndirect effectsPolynesian individuals
2016
Food Label Use is associated with Dietary Quality and Dietary Patterns among Latinos with Type 2 Diabetes
SAMUEL G, Segura‐Pérez S, Shebl F, Hawley N, Damio G, Chhabra J, Vega‐López S, Fernandez M, Pérez‐Escamilla R. Food Label Use is associated with Dietary Quality and Dietary Patterns among Latinos with Type 2 Diabetes. The FASEB Journal 2016, 30 DOI: 10.1096/fasebj.30.1_supplement.674.41.Peer-Reviewed Original ResearchType 2 diabetesFood frequency questionnaireDietary patternsFood label useDietary qualityLabel useDietary intakeHealth disparitiesType 2 diabetes careDiabetes-related knowledgeHealthy dietary patternMultivariable logistic regressionHealthy Eating IndexHealthy food choicesEthnic health disparitiesEducation levelFFQ dataFrequency questionnaireIndependent determinantsDiabetes careSnack patternsDiet managementLatino adultsDiabetesType 2