2024
Analysis of Powassan Virus Genome Sequences from Human Cases Reveals Substantial Genetic Diversity with Implications for Molecular Assay Development
Klontz E, Chowdhury N, Holbrook N, Solomon I, Telford S, Aliota M, Vogels C, Grubaugh N, Helgager J, Hughes H, Velez J, Piantadosi A, Chiu C, Lemieux J, Branda J. Analysis of Powassan Virus Genome Sequences from Human Cases Reveals Substantial Genetic Diversity with Implications for Molecular Assay Development. Viruses 2024, 16: 1653. DOI: 10.3390/v16111653.Peer-Reviewed Original ResearchGenome sequenceDiversity of genomic sequencesHuman infectionsPCR assay designVirus genome sequencesAssay designIn silico analysisBiology of infectionViral genomic dataGenetic diversityGenomic dataSensitivity of PCRGenomeCladePCR assayHuman diseasesVirulent strainsPCR designPowassan virusSequenceImmunocompromised patientsPCRTick-borne virusesAssay developmentClinical diagnostics
2023
Application of Phylodynamic Tools to Inform the Public Health Response to COVID-19: Qualitative Analysis of Expert Opinions
Rich S, Richards V, Mavian C, Magalis B, Grubaugh N, Rasmussen S, Dellicour S, Vrancken B, Carrington C, Fisk-Hoffman R, Danso-Odei D, Chacreton D, Shapiro J, Seraphin M, Hepp C, Black A, Dennis A, Trovão N, Vandamme A, Rasmussen A, Lauzardo M, Dean N, Salemi M, Prosperi M. Application of Phylodynamic Tools to Inform the Public Health Response to COVID-19: Qualitative Analysis of Expert Opinions. JMIR Formative Research 2023, 7: e39409. PMID: 36848460, PMCID: PMC10131930, DOI: 10.2196/39409.Peer-Reviewed Original ResearchPublic health responsePublic health practitionersPublic health partnershipsHealth responseHealth practitionersCOVID-19Public healthSARS-CoV-2 genomic epidemiologyInfectious disease expertsSARS-CoV-2 pandemicHealth partnershipsFocus groupsPandemic responsePublic health professionalsVaccination eraPrecision public healthDisease expertsHealth professionalsEpidemiological investigationsInfectious diseasesMolecular epidemiologistsViral genomic dataFuture outbreaksCOVID-19 responseStrain emergence