2021
Intrahost speciations and host switches played an important role in the evolution of herpesviruses
Brito AF, Baele G, Nahata KD, Grubaugh ND, Pinney JW. Intrahost speciations and host switches played an important role in the evolution of herpesviruses. Virus Evolution 2021, 7: veab025. PMID: 33927887, PMCID: PMC8062258, DOI: 10.1093/ve/veab025.Peer-Reviewed Original ResearchIntrahost speciationHost switchingHost switchesEvolutionary historyTree reconciliationTree reconciliation analysesEvolution of herpesvirusesViral phylogenyHost biogeographyDivergence timingTopological incongruenceCophylogenetic analysesReconciliation analysisHost evolutionPhylogenetic differencesSequence dataGenomic dataViral speciesPhylogenyTemporal incongruenceCospeciationSpeciationImportant roleHostIncongruence
2016
Genetic Drift during Systemic Arbovirus Infection of Mosquito Vectors Leads to Decreased Relative Fitness during Host Switching
Grubaugh ND, Weger-Lucarelli J, Murrieta RA, Fauver JR, Garcia-Luna SM, Prasad AN, Black WC, Ebel GD. Genetic Drift during Systemic Arbovirus Infection of Mosquito Vectors Leads to Decreased Relative Fitness during Host Switching. Cell Host & Microbe 2016, 19: 481-492. PMID: 27049584, PMCID: PMC4833525, DOI: 10.1016/j.chom.2016.03.002.Peer-Reviewed Original ResearchConceptsRelative fitnessMosquito speciesLower relative fitnessWest Nile virusComplex virus populationsSignificant fitness costMosquito-borne RNA virusesHost switchingGenetic driftGenetic diversityAdaptive potentialPopulation expansionFitness costsAvian cellsDeleterious mutationsMutational diversityRNA virusesBridge vectorsViral populationsVirus populationsMosquito vectorsFitnessSpeciesDiversityNile virus