2023
Extensive transmission of SARS-CoV-2 BQ.1* variant in a population with high levels of hybrid immunity: A prevalence survey
Ticona J, Xiao M, Li D, Nery N, Hitchings M, Belitardo E, Fofana M, Victoriano R, Cruz J, de Moraes L, Strobel I, Silva J, do Aragão Filho A, Ribeiro G, Reis M, Costa F, Khouri R, Ko A, Cummings D. Extensive transmission of SARS-CoV-2 BQ.1* variant in a population with high levels of hybrid immunity: A prevalence survey. International Journal Of Infectious Diseases 2023, 139: 159-167. PMID: 38070701, PMCID: PMC10784150, DOI: 10.1016/j.ijid.2023.11.039.Peer-Reviewed Original ResearchThe impact of COVID-19 on microbiological profile and antibiotic consumption in ICU: a retrospective study in an infectious disease hospital in Brazil
de França Diniz Rocha V, da Silva E, Azevedo J, Ribeiro M, Reis M, Barros T, Reis J. The impact of COVID-19 on microbiological profile and antibiotic consumption in ICU: a retrospective study in an infectious disease hospital in Brazil. The Brazilian Journal Of Infectious Diseases 2023, 28: 103705. PMID: 38065221, PMCID: PMC10764251, DOI: 10.1016/j.bjid.2023.103705.Peer-Reviewed Original ResearchConceptsIntensive care unitInfectious Diseases HospitalAntimicrobial resistanceMicrobiological profileCandida sppRetrospective studyTracheal secretionsCarbapenem-resistant A. baumanniiConsequences of antimicrobial resistanceIntensive care unit patient-daysImpact of antimicrobial resistanceMultidrug-resistant Enterococcus faeciumCharacteristics of patientsConsumption of ceftriaxoneConsumption of antibioticsPiperacillin-tazobactamUnique characteristics of patientsA. baumanniiAcinetobacter baumanniiAntibiotic consumptionEnterobacter speciesIncidence densityESKAPE groupClinical culturesKlebsiella pneumoniaeMalaria and COVID-19 coinfection in a non-malaria-endemic area in Brazil
Rocha V, Brasil L, Gomes E, Khouri R, Ferreira G, Vasconcelos B, Gouveia M, Santos T, Reis M, Lacerda M. Malaria and COVID-19 coinfection in a non-malaria-endemic area in Brazil. Revista Da Sociedade Brasileira De Medicina Tropical 2023, 56: e0598-2022. PMID: 37222351, PMCID: PMC10204151, DOI: 10.1590/0037-8682-0598-2022.Peer-Reviewed Original ResearchConceptsCOVID-19 coinfectionSevere acute respiratory syndrome coronavirus 2Acute respiratory syndrome coronavirus 2Respiratory syndrome coronavirus 2Severe vivax malariaIntensive care unitSyndrome coronavirus 2Coronavirus disease 2019Transcription-quantitative PCR resultsSevere malariaCare unitCoronavirus 2Vivax malariaDifferential diagnosisDisease 2019Febrile diseaseEndemic areasPlasmodium vivaxEndemic regionsCoinfectionRapid testMalariaPCR resultsQuantitative PCRHypotension
2022
Plasmodium infection is associated with cross-reactive antibodies to carbohydrate epitopes on the SARS-CoV-2 Spike protein
Lapidus S, Liu F, Casanovas-Massana A, Dai Y, Huck J, Lucas C, Klein J, Filler R, Strine M, Sy M, Deme A, Badiane A, Dieye B, Ndiaye I, Diedhiou Y, Mbaye A, Diagne C, Vigan-Womas I, Mbengue A, Sadio B, Diagne M, Moore A, Mangou K, Diallo F, Sene S, Pouye M, Faye R, Diouf B, Nery N, Costa F, Reis M, Muenker M, Hodson D, Mbarga Y, Katz B, Andrews J, Campbell M, Srivathsan A, Kamath K, Baum-Jones E, Faye O, Sall A, Vélez J, Cappello M, Wilson M, Ben-Mamoun C, Tedder R, McClure M, Cherepanov P, Somé F, Dabiré R, Moukoko C, Ouédraogo J, Boum Y, Shon J, Ndiaye D, Wisnewski A, Parikh S, Iwasaki A, Wilen C, Ko A, Ring A, Bei A. Plasmodium infection is associated with cross-reactive antibodies to carbohydrate epitopes on the SARS-CoV-2 Spike protein. Scientific Reports 2022, 12: 22175. PMID: 36550362, PMCID: PMC9778468, DOI: 10.1038/s41598-022-26709-7.Peer-Reviewed Original ResearchConceptsCross-reactive antibodiesSARS-CoV-2Positive SARS-CoV-2 antibody resultsPositive SARS-CoV-2 antibodiesSARS-CoV-2 reactivitySARS-CoV-2 antibodiesAcute malaria infectionSpike proteinAntibody test resultsPre-pandemic samplesMalaria-endemic countriesPopulation-level immunityMalaria-endemic regionsSpike S1 subunitNon-endemic countriesSARS-CoV-2 spike proteinSARS-CoV-2 proteinsPopulation-level exposureCOVID-19 transmissionMalaria exposureFalse-positive resultsMalaria infectionDisease burdenPlasmodium infectionAntibody resultsStructural factors associated with SARS-CoV-2 infection risk in an urban slum setting in Salvador, Brazil: A cross-sectional survey
Fofana MO, Nery N, Ticona J, de Andrade Belitardo EMM, Victoriano R, Anjos RO, Portilho MM, de Santana MC, dos Santos LL, de Oliveira D, Cruz JS, Muenker MC, Khouri R, Wunder EA, Hitchings MDT, Johnson O, Reis MG, Ribeiro GS, Cummings DAT, Costa F, Ko AI. Structural factors associated with SARS-CoV-2 infection risk in an urban slum setting in Salvador, Brazil: A cross-sectional survey. PLOS Medicine 2022, 19: e1004093. PMID: 36074784, PMCID: PMC9499230, DOI: 10.1371/journal.pmed.1004093.Peer-Reviewed Original ResearchConceptsSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectionAcute respiratory syndrome coronavirus 2 infectionSARS-CoV-2 infection riskUrban slumsSyndrome coronavirus 2 infectionSARS-CoV-2 seroprevalenceSARS-CoV-2 incidenceCoronavirus 2 infectionCross-sectional serosurveyMain outcome measuresUrban slum populationPresence of IgGSARS-CoV-2 spike proteinUrban slum communityCross-sectional surveyUrban slum residentsCumulative incidenceMedian ageRisk factorsOutcome measuresStudy populationHigh seroprevalenceMedian dailyPandemic waveGender distributionReliable estimation of SARS-CoV-2 anti-spike protein IgG titers from single dilution optical density values in serologic surveys
Belitardo E, Nery N, Ticona J, Portilho MM, Mello IO, Ribeiro GS, Reis MG, Costa F, Cummings DAT, Ko AI, Fofana MO. Reliable estimation of SARS-CoV-2 anti-spike protein IgG titers from single dilution optical density values in serologic surveys. Diagnostic Microbiology And Infectious Disease 2022, 104: 115807. PMID: 36162285, PMCID: PMC9428330, DOI: 10.1016/j.diagmicrobio.2022.115807.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 incidenceCommunity-based cohortPopulation-level immunitySARS-CoV-2Large-scale serosurveysELISA optical densityIgG titersIgG ELISAPandemic evolvesSerologic surveyTitersOptical density valuesPopulation-level changesSerosurveyImmunitySingle dilutionSerial dilutionsNODCohortIncidenceELISASerumCOVID-19 vaccine hesitancy and associated factors according to sex: A population-based survey in Salvador, Brazil
Nery N, Ticona J, Cardoso C, Prates A, Vieira H, de Almeida A, da Silva Souza M, dos Reis O, Pellizzaro M, Portilho M, da Anunciação R, Victoriano R, dos Anjos R, Argibay H, Lima D, Mesquita I, Conceição W, Santana P, Oliveira E, Santana P, Brodskyn C, Fraga D, da Silva Solcà M, Reis M, Costa F, Ribeiro G. COVID-19 vaccine hesitancy and associated factors according to sex: A population-based survey in Salvador, Brazil. PLOS ONE 2022, 17: e0262649. PMID: 35061811, PMCID: PMC8782400, DOI: 10.1371/journal.pone.0262649.Peer-Reviewed Original ResearchConceptsCOVID-19 vaccine hesitancyVaccine hesitancyCOVID-19 vaccineCOVID-19 riskCOVID-19 vaccine acceptanceInfluenza vaccination historyPopulation-based surveyCoronavirus disease 2019Less vaccine hesitancyHigher educational levelInfluenza vaccinationVaccination historyMultivariable analysisPrevious diagnosisVaccine acceptanceAssociated FactorsVaccine campaignDisease 2019VaccineComorbiditiesHesitancyCOVID-19VaccinationEducational levelWomen