2023
Dynamics of chikungunya virus transmission in the first year after its introduction in Brazil: A cohort study in an urban community
Anjos R, Portilho M, Jacob-Nascimento L, Carvalho C, Moreira P, Sacramento G, Nery N, de Oliveira D, Cruz J, Cardoso C, Argibay H, Plante K, Plante J, Weaver S, Kitron U, Reis M, Ko A, Costa F, Ribeiro G. Dynamics of chikungunya virus transmission in the first year after its introduction in Brazil: A cohort study in an urban community. PLOS Neglected Tropical Diseases 2023, 17: e0011863. PMID: 38150470, PMCID: PMC10775974, DOI: 10.1371/journal.pntd.0011863.Peer-Reviewed Original ResearchAnalyses of Early ZIKV Genomes Are Consistent with Viral Spread from Northeast Brazil to the Americas
de Moraes L, Portilho M, Vrancken B, Van den Broeck F, Santos L, Cucco M, Tauro L, Kikuti M, Silva M, Campos G, Reis M, Barral A, Barral-Netto M, Boaventura V, Vandamme A, Theys K, Lemey P, Ribeiro G, Khouri R. Analyses of Early ZIKV Genomes Are Consistent with Viral Spread from Northeast Brazil to the Americas. Viruses 2023, 15: 1236. PMID: 37376536, PMCID: PMC10301521, DOI: 10.3390/v15061236.Peer-Reviewed Original ResearchConceptsAcute ZIKV infectionSpread of ZIKVPublic health responseZika virus outbreakClinical symptomsZIKV infectionHealth responseZIKVZIKV genomeViral spreadGenomic surveillanceVirus outbreakInfectionSubsequent disseminationSurveillance effortsZIKV dynamicsFuture surveillance effortsOutbreakEarly stagesZika virus RNA persistence and recovery in water and wastewater: An approach for Zika virus surveillance in resource-constrained settings
Zhu K, Hill C, Muirhead A, Basu M, Brown J, Brinton M, Hayat M, Venegas-Vargas C, Reis M, Casanovas-Massana A, Meschke J, Ko A, Costa F, Stauber C. Zika virus RNA persistence and recovery in water and wastewater: An approach for Zika virus surveillance in resource-constrained settings. Water Research 2023, 241: 120116. PMID: 37270953, PMCID: PMC10330535, DOI: 10.1016/j.watres.2023.120116.Peer-Reviewed Original ResearchConceptsZIKV RNAZIKV outbreakZika virus surveillanceNucleic acid testingZika virus epidemicResource-constrained settingsWidespread diagnostic testingPublic health surveillanceReverse transcription droplet digital PCRTranscription droplet digital PCRAcid testingRNA persistenceDiagnostic testingHealth surveillanceDroplet digital PCRVirus epidemicVirus surveillanceIndividual testingSuch casesDigital PCRSurveillanceOutbreakRNAZIKVRecovery
2022
Unequal burden of Zika-associated microcephaly among populations with public and private healthcare in Salvador, Brazil
Aromolaran A, Araujo K, Ladines-Lim JB, Nery N, do Rosário MS, Rastely VN, Archanjo G, Daltro D, da Silveira Carvalho G, Pimentel K, de Almeida JRM, de Siqueira IC, Ribeiro HC, Oliveira-Filho J, de Oliveira D, Henriques DF, Rodrigues SG, da Costa Vasconcelos P, de Almeida ARP, Sacramento GA, Cruz JS, Sarno M, de Paula Freitas B, Mattos A, Khouri R, Reis MG, Ko AI, Costa F. Unequal burden of Zika-associated microcephaly among populations with public and private healthcare in Salvador, Brazil. International Journal Of Infectious Diseases 2022, 120: 201-204. PMID: 35470025, PMCID: PMC9119857, DOI: 10.1016/j.ijid.2022.04.030.Peer-Reviewed Original ResearchMeSH KeywordsBrazilDelivery of Health CareFemaleHumansInfantMicrocephalyPregnancyPregnancy Complications, InfectiousZika VirusZika Virus InfectionConceptsZIKV exposurePregnant womenSocioeconomic statusRelative disease burdenCongenital Zika syndromeZika virus epidemicLow socioeconomic statusZika syndromeClinical presentationDisease burdenSimilar prevalenceSerologic dataDifferent socioeconomic statusS HospitalHospitalLarge hospitalsMicrocephalyStudy centersVirus epidemicWomenPositive associationInfantsUnequal burdenHigh rateExposure rate
2020
Changes in the dynamics of dengue incidence in South and Central America are possibly due to cross‐population immunity after Zika virus epidemics
Mugabe V, Borja L, Cardoso C, Weaver S, Reis M, Kitron U, Ribeiro G. Changes in the dynamics of dengue incidence in South and Central America are possibly due to cross‐population immunity after Zika virus epidemics. Tropical Medicine And International Health 2020, 26: 272-280. PMID: 33190402, DOI: 10.1111/tmi.13526.Peer-Reviewed Original ResearchMeSH KeywordsCentral AmericaChikungunya virusDengueDengue VirusEpidemicsHumansIncidenceLinear ModelsSouth AmericaZika VirusZika Virus InfectionConceptsDengue casesLaboratory-confirmed dengue casesDENV vaccine developmentSignificant public health implicationsDengue virus infectionDengue incidenceLong-term surveillance studyCross-species immunityPublic health implicationsIncidence of dengueVirus immunityVirus infectionEpidemiological dataSurveillance studyDengue feverZika virusDisease severityVaccine developmentIncidenceZika epidemicAnnual dengue incidenceZika outbreakHealth implicationsImmunityOverall rate
2019
Evaluation of two commercially available chikungunya virus IgM enzyme-linked immunoassays (ELISA) in a setting of concomitant transmission of chikungunya, dengue and Zika viruses
Kikuti M, Tauro L, Moreira P, Nascimento L, Portilho M, Soares G, Weaver S, Reis M, Kitron U, Ribeiro G. Evaluation of two commercially available chikungunya virus IgM enzyme-linked immunoassays (ELISA) in a setting of concomitant transmission of chikungunya, dengue and Zika viruses. International Journal Of Infectious Diseases 2019, 91: 38-43. PMID: 31704226, DOI: 10.1016/j.ijid.2019.11.001.Peer-Reviewed Original ResearchConceptsConvalescent samplesIgM enzymeRT-PCRZika virus transmissionNegative patientsCHIKV infectionAcute samplesZIKV casesConvalescent seraSurveillance studyCHIKV transmissionZika virusCHIKV casesDiagnostic performanceLow specificityVirus transmissionEquivocal resultsTest sensitivitySerumELISA specificityPatientsHigh rateDengueConcomitant transmissionMore equivocal results