2022
Why is leptospirosis hard to avoid for the impoverished? Deconstructing leptospirosis transmission risk and the drivers of knowledge, attitudes, and practices in a disadvantaged community in Salvador, Brazil
Palma F, Costa F, Lustosa R, Mogaji H, de Oliveira D, Souza F, Reis M, Ko A, Begon M, Khalil H. Why is leptospirosis hard to avoid for the impoverished? Deconstructing leptospirosis transmission risk and the drivers of knowledge, attitudes, and practices in a disadvantaged community in Salvador, Brazil. PLOS Global Public Health 2022, 2: e0000408. PMID: 36962720, PMCID: PMC10022107, DOI: 10.1371/journal.pgph.0000408.Peer-Reviewed Original ResearchLow socioeconomic statusLower riskLeptospirosis transmissionSocioeconomic statusIndividual infection riskEnvironmental risk factorsPublic health messagingUrban disadvantaged communitiesKAP variablesMale genderRisk factorsCross-sectional KAP surveyEpidemiological dataHigh-risk activitiesHealth messagingPrevention practicesGreater riskInfection riskInfectious diseasesKAP surveyTransmission riskResidents' knowledgeDisadvantaged communitiesRiskRisk activities
2019
Performance of recombinant chimeric proteins in the serological diagnosis of Trypanosoma cruzi infection in dogs
Leony L, Freitas N, Del-Rei R, Carneiro C, Reis A, Jansen A, Xavier S, Gomes Y, Silva E, Reis M, Fraga D, Celedon P, Zanchin N, Dantas-Torres F, Santos F. Performance of recombinant chimeric proteins in the serological diagnosis of Trypanosoma cruzi infection in dogs. PLOS Neglected Tropical Diseases 2019, 13: e0007545. PMID: 31242195, PMCID: PMC6615644, DOI: 10.1371/journal.pntd.0007545.Peer-Reviewed Original ResearchConceptsCruzi infectionIBMP-8.4Cruzi IgG antibodiesDiagnostic performanceTrypanosoma cruzi infectionAntigenic matrixIgG antibody detectionIBMP-8.3IBMP-8.1IBMP-8.2High diagnostic performanceSuperior diagnostic performanceIgG antibodiesChimeric antigenInfected dogsVisceral leishmaniasisEpidemiological studiesRecombinant chimeric proteinAntibody detectionInfectious diseasesTransmission riskSerological diagnosisDogsROC curveDiagnostic potential
2014
Anti-PR3 and anti-MPO antibodies are not present in sera of patients with pulmonary tuberculosis
Lima I, Oliveira R, Cabral M, Atta A, Marchi S, Reis E, Reis M, Barbosa L, Santiago M. Anti-PR3 and anti-MPO antibodies are not present in sera of patients with pulmonary tuberculosis. Rheumatology International 2014, 34: 1231-1234. PMID: 24719228, DOI: 10.1007/s00296-014-3009-z.Peer-Reviewed Original ResearchConceptsAnti-neutrophil cytoplasmic antibodiesAnti-PR3 antibodiesIndirect immunofluorescencePresence of ANCAPrevalence of ANCAInfectious diseasesComponents of neutrophilsGroup of patientsAnti-MPO antibodiesSera of patientsChest X-rayAnti-PR3Cytoplasmic antibodiesVasculitic syndromesTB patientsPulmonary tuberculosisAutoimmune disordersPresent studyClinical similaritiesSuch antibodiesPatientsELISA kitTuberculosisAntibodiesAutoantibodies
2013
Antibodies to citrullinated peptides in tuberculosis
Lima I, Oliveira R, Atta A, Marchi S, Barbosa L, Reis E, Reis M, Santiago M. Antibodies to citrullinated peptides in tuberculosis. Clinical Rheumatology 2013, 32: 685-687. PMID: 23344687, DOI: 10.1007/s10067-013-2173-y.Peer-Reviewed Original ResearchConceptsAnti-citrullinated peptide antibodiesAnti-MCV antibodiesRheumatoid arthritisHealthy controlsRheumatoid factor positivityRA patientsSymmetric polyarthritisTB patientsPulmonary tuberculosisBone erosionCCP antibodyAutoimmune diseasesHigh incidencePeptide antibodiesPatientsControl groupHigh specificityTuberculosisInfectious diseasesAntibodiesPositivityDiseaseSpecificityMethodological factorsPolyarthritis
2006
Frequency of antiphospholipid antibodies in patients with infectious diseases using three different ELISA methods
Santiago M, Martinelli R, Reis M, Reis E, Ko A, Fontes R, Silva M, Nascimento E, Espinola R, Harris N, Gharavi A, Pierangeli S. Frequency of antiphospholipid antibodies in patients with infectious diseases using three different ELISA methods. Jornal Brasileiro De Patologia E Medicina Laboratorial 2006, 42: 13-17. DOI: 10.1590/s1676-24442006000100004.Peer-Reviewed Original ResearchEnzyme-linked immunosorbent assayStandard enzyme-linked immunosorbent assayAntiphospholipid syndromeELISA kitInfectious diseasesAntiphospholipid antibodiesKala-azarACL ELISASera of patientsFrequency of positivityCases of leptospirosisCases of syphilisDetection of antibodiesAnticardiolipin antibodiesIgG aPLIgM aPLVisceral leishmaniasisELISA techniquePatientsHigh specificityELISA methodImmunosorbent assayDiseaseDiagnostic specificityGp I