2019
Evaluation of two commercially available chikungunya virus IgM enzyme-linked immunoassays (ELISA) in a setting of concomitant transmission of chikungunya, dengue and Zika viruses
Kikuti M, Tauro L, Moreira P, Nascimento L, Portilho M, Soares G, Weaver S, Reis M, Kitron U, Ribeiro G. Evaluation of two commercially available chikungunya virus IgM enzyme-linked immunoassays (ELISA) in a setting of concomitant transmission of chikungunya, dengue and Zika viruses. International Journal Of Infectious Diseases 2019, 91: 38-43. PMID: 31704226, DOI: 10.1016/j.ijid.2019.11.001.Peer-Reviewed Original ResearchConceptsConvalescent samplesIgM enzymeRT-PCRZika virus transmissionNegative patientsCHIKV infectionAcute samplesZIKV casesConvalescent seraSurveillance studyCHIKV transmissionZika virusCHIKV casesDiagnostic performanceLow specificityVirus transmissionEquivocal resultsTest sensitivitySerumELISA specificityPatientsHigh rateDengueConcomitant transmissionMore equivocal resultsPerformance of recombinant chimeric proteins in the serological diagnosis of Trypanosoma cruzi infection in dogs
Leony L, Freitas N, Del-Rei R, Carneiro C, Reis A, Jansen A, Xavier S, Gomes Y, Silva E, Reis M, Fraga D, Celedon P, Zanchin N, Dantas-Torres F, Santos F. Performance of recombinant chimeric proteins in the serological diagnosis of Trypanosoma cruzi infection in dogs. PLOS Neglected Tropical Diseases 2019, 13: e0007545. PMID: 31242195, PMCID: PMC6615644, DOI: 10.1371/journal.pntd.0007545.Peer-Reviewed Original ResearchConceptsCruzi infectionIBMP-8.4Cruzi IgG antibodiesDiagnostic performanceTrypanosoma cruzi infectionAntigenic matrixIgG antibody detectionIBMP-8.3IBMP-8.1IBMP-8.2High diagnostic performanceSuperior diagnostic performanceIgG antibodiesChimeric antigenInfected dogsVisceral leishmaniasisEpidemiological studiesRecombinant chimeric proteinAntibody detectionInfectious diseasesTransmission riskSerological diagnosisDogsROC curveDiagnostic potential
2007
Detection of antinucleosome antibodies in systemic lupus erythematosus
Lima I, Barbosa L, Lopes M, Reis E, Reis M, Colossi K, Abreu M, Ferreira C, Santiago M. Detection of antinucleosome antibodies in systemic lupus erythematosus. Advances In Rheumatology 2007, 47: 160-164. DOI: 10.1590/s0482-50042007000300004.Peer-Reviewed Original ResearchDiagnosis of SLESystemic lupus erythematosusSystemic sclerosisDisease activitySLEDAI scoreLupus erythematosusAntinucleosome antibodiesSLE samplesDisease activity indexCross-sectional studyAnti-DNA antibodiesMean age 35Lack of associationMyositis patientsRheumatology criteriaRheumatologic practiceSLE patientsAge 35American CollegeActivity indexPatientsDiagnosisAntibodiesDiagnostic performanceELISA system