2016
Effectiveness of Albendazole for Hookworm Varies Widely by Community and Correlates with Nutritional Factors: A Cross-Sectional Study of School-Age Children in Ghana.
Humphries D, Nguyen S, Kumar S, Quagraine JE, Otchere J, Harrison LM, Wilson M, Cappello M. Effectiveness of Albendazole for Hookworm Varies Widely by Community and Correlates with Nutritional Factors: A Cross-Sectional Study of School-Age Children in Ghana. American Journal Of Tropical Medicine And Hygiene 2016, 96: 347-354. PMID: 27895280, PMCID: PMC5303035, DOI: 10.4269/ajtmh.16-0682.Peer-Reviewed Original ResearchConceptsEgg reduction rateCross-sectional studyMass drug administrationSchool-aged childrenEffectiveness of albendazoleCure rateDrug AdministrationMid-upper arm circumferenceSoil-transmitted helminth infectionsHost factorsNutritional factorsSingle-dose albendazoleOverall cure rateBlood hemoglobin levelsKintampo North MunicipalitySignificant community-level variationIndividual host factorsWorld Health OrganizationCommon STHHemoglobin levelsArm circumferenceHookworm infectionHelminth infectionsDeworming programsHookworm prevalence
2006
Dietary Iron Content Mediates Hookworm Pathogenesis In Vivo
Held MR, Bungiro RD, Harrison LM, Hamza I, Cappello M. Dietary Iron Content Mediates Hookworm Pathogenesis In Vivo. Infection And Immunity 2006, 74: 289-295. PMID: 16368983, PMCID: PMC1346670, DOI: 10.1128/iai.74.1.289-295.2006.Peer-Reviewed Original ResearchConceptsDay 20 postinfectionGrowth delayIron-restricted dietHigh-iron dietIntestinal worm burdenDietary iron restrictionIron deficiency anemiaBlood hemoglobin levelsDietary iron contentGreater weight lossSignificant growth delayHemoglobin levelsDeficiency anemiaHookworm infectionDiet groupHamster modelSevere diseaseStandard dietUninfected controlsHemoglobin concentrationUninfected animalsWorm burdenDay 10Infected animalsHookworm disease
2003
Oral Transfer of Adult Ancylostoma ceylanicum Hookworms into Permissive and Nonpermissive Host Species
Bungiro RD, Anderson BR, Cappello M. Oral Transfer of Adult Ancylostoma ceylanicum Hookworms into Permissive and Nonpermissive Host Species. Infection And Immunity 2003, 71: 1880-1886. PMID: 12654804, PMCID: PMC152085, DOI: 10.1128/iai.71.4.1880-1886.2003.Peer-Reviewed Original ResearchConceptsBALB/c miceHigh-dose groupHumoral immune responseCD-1 miceLong-term survivalRecovery of parasitesExcretory-secretory productsHemoglobin levelsPrechallenge levelsC57BL/6 miceHookworm infectionC miceWeanling hamstersOral infectionImmune responseMurine modelHookworm larvaeSyrian hamstersMouse strainsTypical infectionsInfectionPrior exposureMiceAdult wormsOral transfer