2018
Interventions to treat cutaneous leishmaniasis in children: A systematic review
Uribe-Restrepo A, Cossio A, Desai MM, Dávalos D, del Mar Castro M. Interventions to treat cutaneous leishmaniasis in children: A systematic review. PLOS Neglected Tropical Diseases 2018, 12: e0006986. PMID: 30550538, PMCID: PMC6310290, DOI: 10.1371/journal.pntd.0006986.Peer-Reviewed Original ResearchConceptsInternational Clinical Trials Registry PlatformAdverse eventsMeglumine antimoniateCutaneous leishmaniasisSystematic reviewClinical trialsManagement of CLClinical Trials Registry PlatformOld World cutaneous leishmaniasisTreatment of CLIntralesional meglumine antimoniateOld World CLEfficacy of cryotherapySerious adverse eventsTrials Registry PlatformHarms of interventionsRisk of biasEfficacy of treatmentFull-text reviewAmerican cutaneous leishmaniasisPROSPERO International registerRegistry PlatformCohort studySystemic therapyPediatric population
2017
Clinical and parasitological factors in parasite persistence after treatment and clinical cure of cutaneous leishmaniasis
Martínez-Valencia AJ, Daza-Rivera CF, Rosales-Chilama M, Cossio A, Rincón E, Desai MM, Saravia NG, Gómez MA. Clinical and parasitological factors in parasite persistence after treatment and clinical cure of cutaneous leishmaniasis. PLOS Neglected Tropical Diseases 2017, 11: e0005713. PMID: 28704369, PMCID: PMC5526576, DOI: 10.1371/journal.pntd.0005713.Peer-Reviewed Original ResearchConceptsCutaneous leishmaniasisParasite persistencePercent of patientsInitiation of treatmentEnd of treatmentViability of LeishmaniaDisease reactivationTonsillar mucosaClinical cureClinical resolutionTreatment initiationProtective immunityMeglumine antimoniatePersistent infectionMucosal tissuesPrevious episodesTherapeutic cureParasitological factorsProtective factorsPatientsParasitological parametersTreatmentLeishmaniasisWeeksHigher proportion