2024
Intrinsic connectivity demonstrates a shared role of the posterior cingulate for cue reactivity in both gambling and cocaine use disorders
Vaccaro A, Lacadie C, Potenza M. Intrinsic connectivity demonstrates a shared role of the posterior cingulate for cue reactivity in both gambling and cocaine use disorders. Addictive Behaviors 2024, 155: 108027. PMID: 38581751, PMCID: PMC11273263, DOI: 10.1016/j.addbeh.2024.108027.Peer-Reviewed Original ResearchConceptsCocaine use disorderPosterior cingulate cortexCue reactivityBehavioral addictionsUse disorderGambling disorderPosterior cingulatePosterior cingulate cortex connectivityHealthy comparison subjectsIntrinsic connectivity distributionIntervention developmentCocaine cuesFMRI taskAddictive disordersCingulate cortexComparison subjectsNeurobiological foundationsSad videosDecreased connectivityFunctional connectivityCocainePost hoc analysisAddictionRelevant to maintenanceGambling
2023
Anandamide and 2-arachidonoylglycerol baseline plasma concentrations and their clinical correlate in gambling disorder
Baenas I, Solé-Morata N, Granero R, Fernández-Aranda F, Pujadas M, Mora-Maltas B, Lucas I, Gómez-Peña M, Moragas L, del Pino-Gutiérrez A, Tapia J, de la Torre R, Potenza M, Jiménez-Murcia S. Anandamide and 2-arachidonoylglycerol baseline plasma concentrations and their clinical correlate in gambling disorder. European Psychiatry 2023, 66: e97. PMID: 37937379, PMCID: PMC10755577, DOI: 10.1192/j.eurpsy.2023.2460.Peer-Reviewed Original ResearchConceptsHealthy control subjectsPlasma concentrationsBaseline plasma concentrationsPeripheral blood samplesBrain reward pathwaysGambling disorderSemi-structured clinical interviewConcentrations of endocannabinoidsNeuropsychological variablesAddiction-related disordersGD severityClinical correlatesControl subjectsAdult outpatientsEndocannabinoid systemBlood samplesClinical InterviewPlasma AEA concentrationsEndogenous ligandReward pathwayClinical groupsEndocannabinoidsAEA concentrationsPsychometric assessmentNeurobiological substratesPlasma concentration of leptin is related to food addiction in gambling disorder: Clinical and neuropsychological implications
Etxandi M, Baenas I, Mora-Maltas B, Granero R, Fernández-Aranda F, Tovar S, Solé-Morata N, Lucas I, Casado S, Gómez-Peña M, Moragas L, del Pino-Gutiérrez A, Tapia J, Valenciano-Mendoza E, Potenza M, Gearhardt A, Diéguez C, Jiménez-Murcia S. Plasma concentration of leptin is related to food addiction in gambling disorder: Clinical and neuropsychological implications. Journal Of Behavioral Addictions 2023, 12: 1019-1031. PMID: 38141066, PMCID: PMC10786224, DOI: 10.1556/2006.2023.00051.Peer-Reviewed Original ResearchConceptsBody mass indexLeptin concentrationsFood addictionPlasma concentrationsHigher body mass indexAppetite-regulating hormonesYale Food Addiction Scale 2.0Gambling disorderSemi-structured clinical interviewLiver-expressed antimicrobial peptide 2Clinical featuresMass indexAppetite regulationHormonal variablesBlood samplesLifetime diagnosisPatientsAntimicrobial peptide 2Clinical InterviewNeuropsychological featuresPoor inhibitory controlAnthropometric variablesEndocrine measuresHormonal concentrationsLeptinGambling participation among Connecticut adolescents from 2007 to 2019: Potential risk and protective factors
Stefanovics E, Gueorguieva R, Zhai Z, Potenza M. Gambling participation among Connecticut adolescents from 2007 to 2019: Potential risk and protective factors. Journal Of Behavioral Addictions 2023, 12: 490-499. PMID: 37335777, PMCID: PMC10316163, DOI: 10.1556/2006.2023.00027.Peer-Reviewed Original ResearchConceptsPrevalence of gamblingGambling participationPatterns of gamblingSocial supportSocial support programsGambling advertisementsTraumatic experiencesMedia coverageState of ConnecticutSocio-demographic characteristicsAffective concernsSubstance useConnecticut high school studentsGamblingAdolescent gamblingAnonymous self-completed questionnairePotential risk factorsParticipationSupport programsPublic health concernSelf-completed questionnaireCurrent substance useSocio-demographic dataCross-sectional surveyWarrants further studyChronically homeless veterans with gambling disorder: Epidemiology, clinical correlates, and traumatic experiences
Stefanovics E, Potenza M, Szymkowiak D, Tsai J. Chronically homeless veterans with gambling disorder: Epidemiology, clinical correlates, and traumatic experiences. Journal Of Psychiatric Research 2023, 164: 118-124. PMID: 37339548, DOI: 10.1016/j.jpsychires.2023.05.062.Peer-Reviewed Original ResearchConceptsPsychiatric treatmentGambling disorderChi-square testChronic homelessnessClinical correlatesDescriptive epidemiologyLow educational attainmentElevated oddsSuicidal thoughtsLogistic regressionTraumatic experiencesMental healthSubstance useHomeless veteransHomeless ProgramVeteransTreatmentLower ratesEpidemiologyBehavioral concernsDisordersStudy of factorsCorrelatesAnalysis of varianceEducational attainmentA systematic review and meta-analysis of risky decision-making in specific domains of problematic use of the internet: Evidence across different decision-making tasks
Müller S, Antons S, Wegmann E, Ioannidis K, King D, Potenza M, Chamberlain S, Brand M. A systematic review and meta-analysis of risky decision-making in specific domains of problematic use of the internet: Evidence across different decision-making tasks. Neuroscience & Biobehavioral Reviews 2023, 152: 105271. PMID: 37277009, DOI: 10.1016/j.neubiorev.2023.105271.Peer-Reviewed Original ResearchConnectome-based prediction of craving in gambling disorder and cocaine use disorder
Antons S, Yip S, Lacadie C, Dadashkarimi J, Scheinost D, Brand M, Potenza M. Connectome-based prediction of craving in gambling disorder and cocaine use disorder. Dialogues In Clinical Neuroscience 2023, 25: 33-42. PMID: 37190759, PMCID: PMC10190201, DOI: 10.1080/19585969.2023.2208586.Peer-Reviewed Original ResearchConceptsCocaine use disorderGambling disorderBehavioral addictionsCue-reactivity taskComponents of memoryGeneral neural mechanismCommon neural networkFunctional magnetic resonanceMedial frontal regionsDefault mode networkFeatures of addictionAutobiographical memoryValence ratingsMeta-analytic dataPrefrontal regionsNeural mechanismsPrefrontal cortexFronto-parietalFrontal regionsMotor imageryMotor/Diverse sampleLimbic networkNeural connectivityCravingClinical Correlates of Sports Betting: A Systematic Review
Valenciano-Mendoza E, Mora-Maltas B, Mestre-Bach G, Munguía L, Richard J, Derevensky J, Potenza M, Jiménez-Murcia S. Clinical Correlates of Sports Betting: A Systematic Review. Journal Of Gambling Studies 2023, 39: 579-624. PMID: 37004597, PMCID: PMC10066997, DOI: 10.1007/s10899-023-10196-0.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsSystematic reviewMultiple sociodemographic variablesGambling disorderNCBI/PubMedSelf-administered instrumentAPA PsycINFO databasesClinical correlatesCo-occurring psychopathologyGeneral populationPRISMA guidelinesPrevention strategiesClinical diagnosisPsycINFO databasesSubstance useSociodemographic variablesAddictive disordersRelevant studiesVulnerable individualsHigh impulsivityDisordersCertain pathologiesImpulsive malesGambling-related variablesAddictive behaviorsGroups of participantsRelationships Between Impulsivity, Methamphetamine use Disorder and Gambling Disorder
Wang Y, Zuo J, Hao W, Wu L, Liu F, Wang Q, He L, Peng P, Zhou Y, Li M, Yang Q, Wang X, Liu T, Potenza M. Relationships Between Impulsivity, Methamphetamine use Disorder and Gambling Disorder. Journal Of Gambling Studies 2023, 39: 1635-1650. PMID: 36973505, DOI: 10.1007/s10899-023-10201-6.Peer-Reviewed Original ResearchConceptsMethamphetamine use disorderUse disordersMethamphetamine usePotential risk factorsDrug use characteristicsGambling disorderFirst sexual activityClinical characteristicsClinical featuresDrug rehabilitation centersRisk factorsHigh prevalenceDichotomous logistic regressionIndependent sample t-testRehabilitation centerCompulsory drug rehabilitation centerNon-planning impulsivityLogistic regressionSample t-testPrevalenceDisordersSexual activityBarratt Impulsiveness Scale-11T-testFamily membersFeatures Linked to Treatment Outcomes in Behavioral Addictions and Related Disorders
Mestre-Bach G, Potenza M. Features Linked to Treatment Outcomes in Behavioral Addictions and Related Disorders. International Journal Of Environmental Research And Public Health 2023, 20: 2873. PMID: 36833569, PMCID: PMC9957199, DOI: 10.3390/ijerph20042873.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsPotential Biological Markers and Treatment Implications for Binge Eating Disorder and Behavioral Addictions
Mestre-Bach G, Potenza M. Potential Biological Markers and Treatment Implications for Binge Eating Disorder and Behavioral Addictions. Nutrients 2023, 15: 827. PMID: 36839185, PMCID: PMC9962023, DOI: 10.3390/nu15040827.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsInternet gaming disorderGambling disorderVentral striatumBehavioral addictionsBinge Eating DisorderReward processingEating DisordersGaming disorderReward systemTreatment implicationsBrain regionsBrain changesTreatment-related changesAddictionDisordersBingePotential biological markersPossible biomarkersBiological markersMore evidenceSpecific roleProcessingInterventionImplicationsCircuitry
2022
Obsessive-compulsive, harm-avoidance and persistence tendencies in patients with gambling, gaming, compulsive sexual behavior and compulsive buying-shopping disorders/concerns
Mestre-Bach G, Granero R, Fernández-Aranda F, Potenza M, Jiménez-Murcia S. Obsessive-compulsive, harm-avoidance and persistence tendencies in patients with gambling, gaming, compulsive sexual behavior and compulsive buying-shopping disorders/concerns. Addictive Behaviors 2022, 139: 107591. PMID: 36587418, DOI: 10.1016/j.addbeh.2022.107591.Peer-Reviewed Original ResearchConceptsObsessive-compulsive featuresTreatment-seeking patientsObsessive-compulsive subscaleBehavioral addictionsDifferent behavioural addictionsHarm avoidanceDifferent addictionsSymptom ChecklistObsessive-compulsive measuresLower scoresBuying-shopping disorderInternet gaming disorderCompulsive sexual behavior disorderCompulsive sexual behaviorSexual behavior disorderCharacter Inventory-RevisedGambling disorderGaming disorderCharacter InventoryClinical populationsInventory-RevisedPersonality profilesBehavior disorderHigher scoresEmpirical groupAre Signals Regulating Energy Homeostasis Related to Neuropsychological and Clinical Features of Gambling Disorder? A Case–Control Study
Etxandi M, Baenas I, Mora-Maltas B, Granero R, Fernández-Aranda F, Tovar S, Solé-Morata N, Lucas I, Casado S, Gómez-Peña M, Moragas L, del Pino-Gutiérrez A, Codina E, Valenciano-Mendoza E, Potenza M, Diéguez C, Jiménez-Murcia S. Are Signals Regulating Energy Homeostasis Related to Neuropsychological and Clinical Features of Gambling Disorder? A Case–Control Study. Nutrients 2022, 14: 5084. PMID: 36501114, PMCID: PMC9736671, DOI: 10.3390/nu14235084.Peer-Reviewed Original ResearchConceptsGambling disorderSemi-structured clinical interviewHigher impulsivity levelsBad psychological stateDysfunctional personality profileHigher cognitive impairmentGd presenceCognitive flexibilityNeuropsychological factorsSubstance use disordersDecision-making strategiesCognitive dimensionsImpulsivity levelsPsychological statePsychometric batteryVulnerability pathwaysHealthy controlsPersonality profilesBody mass indexCognitive impairmentClinical InterviewUse disordersGD groupPresent studyEnergy homeostasisRoles for Alexithymia, Emotion Dysregulation and Personality Features in Gambling Disorder: A Network Analysis
Mestre-Bach G, Granero R, Fernández-Aranda F, Potenza M, Jiménez-Murcia S. Roles for Alexithymia, Emotion Dysregulation and Personality Features in Gambling Disorder: A Network Analysis. Journal Of Gambling Studies 2022, 39: 1207-1223. PMID: 36434175, DOI: 10.1007/s10899-022-10164-0.Peer-Reviewed Original ResearchPrevalence and Clinical Characteristics of Recreational and At-Risk/Problematic Gambling in a National Sample of U.S. Military Veterans
Stefanovics E, Potenza M, Tsai J, Pietrzak R. Prevalence and Clinical Characteristics of Recreational and At-Risk/Problematic Gambling in a National Sample of U.S. Military Veterans. Journal Of Gambling Studies 2022, 39: 1077-1097. PMID: 36378356, DOI: 10.1007/s10899-022-10165-z.Peer-Reviewed Original ResearchConceptsCurrent psychiatric diagnosisU.S. military veteransUse disordersPsychiatric diagnosisMilitary veteransU.S. veteransDrug use disordersMental health treatmentSubstance use disordersChi-square testClinical characteristicsTrauma burdenNational HealthAdjusted associationsRoutine screeningClinical measuresRecreational gamblingCurrent prevalenceMale veteransHealth treatmentHigher household incomeSuicidal ideationVeterans StudyLogistic regressionExtensive involvement
2020
Neurobiology of cue-reactivity, craving, and inhibitory control in non-substance addictive behaviors
Antons S, Brand M, Potenza MN. Neurobiology of cue-reactivity, craving, and inhibitory control in non-substance addictive behaviors. Journal Of The Neurological Sciences 2020, 415: 116952. PMID: 32534370, DOI: 10.1016/j.jns.2020.116952.Peer-Reviewed Original ResearchConceptsNon-substance addictive behaviorsAddictive behaviorsInhibitory controlPotential neurobiological mechanismsExecutive functioningSalience attributionNeurobiological foundationsSubstance use disordersNeurobiological factorsNeurobiological mechanismsBrain networksLife domainsRewarding behaviorNegative consequencesHabit formationCravingSpecific disordersNeurobiologyNeurochemical pathwaysAddictionFunctional impairmentFuture directionsSexual activityDisordersCuesSelf-injurious behavior and gambling-related attitudes, perceptions and behaviors in adolescents
Farhat LC, Roberto AJ, Wampler J, Steinberg MA, Krishnan-Sarin S, Hoff RA, Potenza MN. Self-injurious behavior and gambling-related attitudes, perceptions and behaviors in adolescents. Journal Of Psychiatric Research 2020, 124: 77-84. PMID: 32126363, DOI: 10.1016/j.jpsychires.2020.02.016.Peer-Reviewed Original Research
2018
Searching for Replicable Dopamine-Related Findings in Gambling Disorder
Potenza MN. Searching for Replicable Dopamine-Related Findings in Gambling Disorder. Biological Psychiatry 2018, 83: 984-986. PMID: 29804589, DOI: 10.1016/j.biopsych.2018.04.011.Peer-Reviewed Original ResearchCorrelates of frequent gambling and gambling-related chasing behaviors in individuals with schizophrenia-spectrum disorders
Yakovenko I, Fortgang R, Prentice J, Hoff RA, Potenza MN. Correlates of frequent gambling and gambling-related chasing behaviors in individuals with schizophrenia-spectrum disorders. Journal Of Behavioral Addictions 2018, 7: 375-383. PMID: 29788756, PMCID: PMC6174591, DOI: 10.1556/2006.7.2018.31.Peer-Reviewed Original ResearchMeSH KeywordsAge of OnsetAmbulatory CareCross-Sectional StudiesFemaleGamblingGenetic Predisposition to DiseaseHumansMaleMiddle AgedMotivationPsychiatric Status Rating ScalesPsychotic DisordersRisk FactorsSchizophreniaSchizophrenic PsychologySelf ReportSeverity of Illness IndexSubstance-Related DisordersConceptsSchizophrenia/schizoaffective disorderSchizoaffective disorderCo-occurring disordersDSM-IV criteriaSymptoms of schizophreniaSchizophrenia spectrum disordersPsychotic spectrum disordersHigh prevalenceFamily historyGreater gambling involvementSchizophreniaDisordersLower functioningContinuum of severityHallmark featureMethods DataSample of individualsGambling disorderIndividualsCorrelates
2001
Schizophrenia and Pathological Gambling
POTENZA M, CHAMBERS R. Schizophrenia and Pathological Gambling. American Journal Of Psychiatry 2001, 158: 497-a-498. PMID: 11229999, DOI: 10.1176/appi.ajp.158.3.497-a.Peer-Reviewed Original Research