2023
Non-targeted analysis (NTA) and suspect screening analysis (SSA): a review of examining the chemical exposome
Manz K, Feerick A, Braun J, Feng Y, Hall A, Koelmel J, Manzano C, Newton S, Pennell K, Place B, Godri Pollitt K, Prasse C, Young J. Non-targeted analysis (NTA) and suspect screening analysis (SSA): a review of examining the chemical exposome. Journal Of Exposure Science & Environmental Epidemiology 2023, 33: 524-536. PMID: 37380877, PMCID: PMC10403360, DOI: 10.1038/s41370-023-00574-6.Peer-Reviewed Original ResearchConceptsHigh-resolution mass spectrometryNon-targeted analysisExposure mediaChemical spaceSoils/sedimentsMass spectrometryPolyfluoroalkyl substancesSemi-volatile organic compoundsChemical exposomePolyaromatic hydrocarbonsLiquid chromatographyEnvironmental mediaOrganic compoundsGC-HRMSHuman exposureLC-HRMSAnalytical platformConsumer productsChemical exposureSedimentsPesticidesEnvironmental chemicalsChemicalsExposure sourcesSpectrometryAdequacy of stationary measurements as proxies for residential personal exposure to gaseous and particle air pollutants
González Serrano V, Lin E, Godri Pollitt K, Licina D. Adequacy of stationary measurements as proxies for residential personal exposure to gaseous and particle air pollutants. Environmental Research 2023, 231: 116197. PMID: 37224948, DOI: 10.1016/j.envres.2023.116197.Peer-Reviewed Original ResearchConceptsVolatile organic compoundsOrganic compoundsTotal volatile organic compoundsPassive samplersSingle COCompoundsCOPollutantsCarbon dioxideStationary samplesEnvironmental monitorsReal-time sensorsSVOCsParticlesHigh concentrationsPersonal exposure monitorsAirborne pollutantsInhalation exposure assessmentAir quality monitoringDioxideAir pollutantsParticle number concentrationConcentrationSamplerParticle pollutants
2022
Personal airborne chemical exposure and epigenetic ageing biomarkers in healthy Chinese elderly individuals: Evidence from mixture approaches
Shi W, Gao X, Cao Y, Chen Y, Cui Q, Deng F, Yang B, Lin E, Fang J, Li T, Tang S, Godri Pollitt K, Shi X. Personal airborne chemical exposure and epigenetic ageing biomarkers in healthy Chinese elderly individuals: Evidence from mixture approaches. Environment International 2022, 170: 107614. PMID: 36375280, DOI: 10.1016/j.envint.2022.107614.Peer-Reviewed Original ResearchConceptsEpigenetic ageing biomarkersPolycyclic aromatic hydrocarbonsOrganic chemical contaminantsVolatile organic compoundsElderly individualsChemical exposureAge-related adverse effectsBayesian kernel machine regression (BKMR) modelsOrganic compoundsAging biomarkersChinese elderly individualsOrganic chemicalsHealthy elderly peopleLinear mixed-effects regression modelsHealthy elderly individualsAirborne chemical exposuresQuantile sum (WQS) regressionPassive samplersNitroaromaticsMixed effects regression modelsEpigenetic biomarkersChemical contaminantsPersonal chemical exposureChlorinated hydrocarbonsChemical mixtures
2021
Exploring personal chemical exposures in China with wearable air pollutant monitors: A repeated-measure study in healthy older adults in Jinan, China
Guo P, Lin EZ, Koelmel JP, Ding E, Gao Y, Deng F, Dong H, Liu Y, Cha Y, Fang J, Shi X, Tang S, Godri Pollitt KJ. Exploring personal chemical exposures in China with wearable air pollutant monitors: A repeated-measure study in healthy older adults in Jinan, China. Environment International 2021, 156: 106709. PMID: 34153889, DOI: 10.1016/j.envint.2021.106709.Peer-Reviewed Original ResearchConceptsVolatile organic compoundsPolycyclic aromatic hydrocarbonsAirborne chemical contaminantsPersonal exposure profilesPassive air samplersOrganic compoundsPassive samplersChemical classesChemical contaminantsChemical analysisPersonal chemical exposureCertain polycyclic aromatic hydrocarbonsChemical exposureAirborne compoundsAirborne contaminantsCompoundsAromatic hydrocarbonsContaminantsAir monitoring sitesComprehensive characterizationPhthalateNitroaromaticsRepeated-measures studyAir samplerNitrobenzeneSurvey of airborne organic compounds in residential communities near a natural gas compressor station: Response to community concern
Vollet Martin KA, Lin EZ, Hilbert TJ, Godri Pollitt KJ, Haynes EN. Survey of airborne organic compounds in residential communities near a natural gas compressor station: Response to community concern. Environmental Advances 2021, 5: 100076. PMID: 36185588, PMCID: PMC9523739, DOI: 10.1016/j.envadv.2021.100076.Peer-Reviewed Original ResearchSemi-volatile organic compoundsVolatile organic compoundsOrganic compoundsNatural gas compressor stationGas compressor stationsAirborne organic compoundsCompressor stationsPassive air samplersAirborne organicsElevated pollutant levelsNaphthalene derivativesSumma canistersAir sampling campaignsCompoundsVOC concentrationsVOC exposureHealth effectsContaminant levelsIndoor air contaminant levelsPipeline networkGas flowAir qualitySerious health effectsAir contaminantsCommunity members' concernsHead, Shoulders, Knees, and Toes: Placement of Wearable Passive Samplers Alters Exposure Profiles Observed
Koelmel JP, Lin EZ, Nichols A, Guo P, Zhou Y, Pollitt K. Head, Shoulders, Knees, and Toes: Placement of Wearable Passive Samplers Alters Exposure Profiles Observed. Environmental Science And Technology 2021, 55: 3796-3806. PMID: 33625210, DOI: 10.1021/acs.est.0c05522.Peer-Reviewed Original ResearchConceptsSemivolatile organic compoundsOrganic compoundsGas chromatography-high resolution mass spectrometryPassive samplersHigh-resolution mass spectrometryVolatile organic compoundsPersonal exposure profilesChemicals of concernMass spectrometryChemicalsExposure dynamicsExposure profilesCompoundsMajor risk factorComprehensive characterizationPersonal exposureAirborne contaminantsContaminant exposureRisk factorsInhalation routeEpidemiological studiesChemical exposureSpectrometrySamplerParticipants' wrists
2020
Dried blood spots for the identification of bioaccumulating organic compounds: Current challenges and future perspectives
Jobst KJ, Arora A, Pollitt KG, Sled JG. Dried blood spots for the identification of bioaccumulating organic compounds: Current challenges and future perspectives. Current Opinion In Environmental Science & Health 2020, 15: 66-73. PMID: 33073071, PMCID: PMC7560987, DOI: 10.1016/j.coesh.2020.07.001.Peer-Reviewed Original ResearchOrganic compoundsTrace level contaminantsAnalytical chemistryArt mass spectrometryMass spectrometryField of exposomicsChemical pollutantsMost environmental exposuresCompoundsCurrent challengesConstituent compoundsFuture perspectivesChemistryDBS analysisSpectrometryPollutantsExogenous chemicalsContaminantsChemicalsDry blood spotsExposomicsMixtureExposomeReliable approachCharacterization and comparison of PM2.5 oxidative potential assessed by two acellular assays
Gao D, Pollitt K, Mulholland J, Russell A, Weber R. Characterization and comparison of PM2.5 oxidative potential assessed by two acellular assays. Atmospheric Chemistry And Physics 2020, 20: 5197-5210. DOI: 10.5194/acp-20-5197-2020.Peer-Reviewed Original ResearchWater-soluble CuOP assaysMetal ionsOxidative potentialMetal-metal interactionsChemical componentsHumic-like substancesAscorbic acidSynthetic respiratory tract lining fluidDepletion of dithiothreitolMetal speciesOrganic compoundsPM2.5 oxidative potentialBrown carbonMajor chemical componentsOPGSHIonsRespiratory tract lining fluidAcellular assaysParticle composition dataElemental carbonCuCarbonOPAAOPDTT
2017
Biomonitoring-based exposure assessment of benzene, toluene, ethylbenzene and xylene among workers at petroleum distribution facilities
Heibati B, Pollitt K, Charati JY, Ducatman A, Shokrzadeh M, Karimi A, Mohammadyan M. Biomonitoring-based exposure assessment of benzene, toluene, ethylbenzene and xylene among workers at petroleum distribution facilities. Ecotoxicology And Environmental Safety 2017, 149: 19-25. PMID: 29145162, DOI: 10.1016/j.ecoenv.2017.10.070.Peer-Reviewed Original ResearchConceptsGas chromatography-mass spectrometrySolid-phase microextractionChromatography-mass spectrometryVolatile organic compoundsOrganic compoundsPpb tolueneMass spectrometryPassive samplersPersonal passive samplersConcentrations of BTEXPpb benzeneBenzeneBTEX compoundsTolueneUrinary BTEX levelsOil distribution companyPersonal exposureXylenePersonal air exposuresBTEXCompoundsEthylbenzeneOccupational health concernAir exposureRapid method