Air Pollution and Pediatric Respiratory Hospitalizations: Effect Modification by Particle Constituents and Oxidative Potential.
Korsiak J, Lavigne E, You H, Pollitt K, Kulka R, Hatzopoulou M, Evans G, Burnett RT, Weichenthal S. Air Pollution and Pediatric Respiratory Hospitalizations: Effect Modification by Particle Constituents and Oxidative Potential. American Journal Of Respiratory And Critical Care Medicine 2022, 206: 1370-1378. PMID: 35802828, DOI: 10.1164/rccm.202205-0896oc.Peer-Reviewed Original ResearchConceptsRespiratory hospitalizationsConditional logistic regression modelsPediatric respiratory hospitalizationsFine particulate air pollutionCase-crossover studyLogistic regression modelsParticulate air pollutionOxidant gasesRespiratory healthEffect modificationOdds ratioHospitalizationParticle oxidative potentialStrong associationConfidence intervalsOxidative potentialMedianPositive associationChildrenAssociationMedian valueRegression modelsFine particulate matterOutdoor fine particlesAir pollutionLong-term Exposure to Oxidant Gases and Mortality: Effect Modification by PM2.5 Transition Metals and Oxidative Potential
Toyib O, Lavigne E, Traub A, Umbrio D, You H, Ripley S, Pollitt K, Shin T, Kulka R, Jessiman B, Tjepkema M, Martin R, Stieb DM, Hatzopoulou M, Evans G, Burnett RT, Weichenthal S. Long-term Exposure to Oxidant Gases and Mortality: Effect Modification by PM2.5 Transition Metals and Oxidative Potential. Epidemiology 2022, 33: 767-776. PMID: 36165987, PMCID: PMC9531968, DOI: 10.1097/ede.0000000000001538.Peer-Reviewed Original ResearchConceptsLong-term exposureOxidative stressFine particulate air pollutionProportional hazards modelAir pollution health effectsHealth impactsObserved health impactsParticulate air pollutionCohort studyMortality outcomesOxidant gasesEffect modificationInterquartile increaseHazards modelAdverse health impactsNonaccidental mortalityGSH levelsHealth effectsMortalityLand use regression modelsOxidative potentialMedianRegression modelsExposurePM 2.5