2022
Air Pollution and Pediatric Respiratory Hospitalizations: Effect Modification by Particle Constituents and Oxidative Potential.
Korsiak J, Lavigne E, You H, Pollitt K, Kulka R, Hatzopoulou M, Evans G, Burnett RT, Weichenthal S. Air Pollution and Pediatric Respiratory Hospitalizations: Effect Modification by Particle Constituents and Oxidative Potential. American Journal Of Respiratory And Critical Care Medicine 2022, 206: 1370-1378. PMID: 35802828, DOI: 10.1164/rccm.202205-0896oc.Peer-Reviewed Original ResearchConceptsRespiratory hospitalizationsConditional logistic regression modelsPediatric respiratory hospitalizationsFine particulate air pollutionCase-crossover studyLogistic regression modelsParticulate air pollutionOxidant gasesRespiratory healthEffect modificationOdds ratioHospitalizationParticle oxidative potentialStrong associationConfidence intervalsOxidative potentialMedianPositive associationChildrenAssociationMedian valueRegression modelsFine particulate matterOutdoor fine particlesAir pollutionPersonal air pollutant exposure monitoring in South African children in the VHEMBE birth cohort
DeLay K, Lin EZ, Koelmel JP, Bornman R, Obida M, Chevrier J, Godri Pollitt KJ. Personal air pollutant exposure monitoring in South African children in the VHEMBE birth cohort. Environment International 2022, 170: 107524. PMID: 36260950, PMCID: PMC9982749, DOI: 10.1016/j.envint.2022.107524.Peer-Reviewed Original ResearchConceptsBirth cohortMalaria controlEnvironment (MACE) birth cohortVenda Health ExaminationEnvironmental exposuresBurden of diseaseIndoor residual sprayingSouth African childrenHousehold air pollutionMiddle-income countriesHealth examinationNon-invasive methodAfrican childrenPersonal exposure assessmentResidual sprayingExposure levelsPersonal exposureExposure assessmentExposure monitoringRural regionsChildrenHigh exposureEnvironmental contaminantsCohortExposure
2016
Trace metal exposure is associated with increased exhaled nitric oxide in asthmatic children
Godri Pollitt KJ, Maikawa CL, Wheeler AJ, Weichenthal S, Dobbin NA, Liu L, Goldberg MS. Trace metal exposure is associated with increased exhaled nitric oxide in asthmatic children. Environmental Health 2016, 15: 94. PMID: 27586245, PMCID: PMC5009709, DOI: 10.1186/s12940-016-0173-5.Peer-Reviewed Original ResearchConceptsAsthmatic childrenIQR increaseNitric oxideEmergency room visitsExacerbation of symptomsPersonal daily exposureAcute health effectsResultsA positive associationElevated FeNOFeNO responseAirway inflammationRoom visitsMarker of trafficDaily exposureAsthma experienceConsecutive daysFeNOChildren's exposureHealth effectsPersonal samplesChildrenPositive associationExposureFine particulate matterAmbient PM2.5Particulate Oxidative Burden as a Predictor of Exhaled Nitric Oxide in Children with Asthma
Maikawa CL, Weichenthal S, Wheeler AJ, Dobbin NA, Smargiassi A, Evans G, Liu L, Goldberg MS, Pollitt KJ. Particulate Oxidative Burden as a Predictor of Exhaled Nitric Oxide in Children with Asthma. Environmental Health Perspectives 2016, 124: 1616-1622. PMID: 27152705, PMCID: PMC5047770, DOI: 10.1289/ehp175.Peer-Reviewed Original ResearchOxidative burdenAirway inflammationNitric oxideAsthmatic school-aged childrenExhaled Nitric OxideReactive oxygen speciesPM2.5 personal exposureFeNO levelsFeNO responseCorticosteroid useAsthmatic symptomsAsthmatic childrenSchool-aged childrenRespiratory tractOxygen speciesEpidemiological studiesFeNOFluid liningConsecutive daysPersonal exposurePersonal exposure samplesAsthmaBurdenAllergyChildren