2022
Long-term Exposure to Oxidant Gases and Mortality: Effect Modification by PM2.5 Transition Metals and Oxidative Potential
Toyib O, Lavigne E, Traub A, Umbrio D, You H, Ripley S, Pollitt K, Shin T, Kulka R, Jessiman B, Tjepkema M, Martin R, Stieb DM, Hatzopoulou M, Evans G, Burnett RT, Weichenthal S. Long-term Exposure to Oxidant Gases and Mortality: Effect Modification by PM2.5 Transition Metals and Oxidative Potential. Epidemiology 2022, 33: 767-776. PMID: 36165987, PMCID: PMC9531968, DOI: 10.1097/ede.0000000000001538.Peer-Reviewed Original ResearchConceptsLong-term exposureOxidative stressFine particulate air pollutionProportional hazards modelAir pollution health effectsHealth impactsObserved health impactsParticulate air pollutionCohort studyMortality outcomesOxidant gasesEffect modificationInterquartile increaseHazards modelAdverse health impactsNonaccidental mortalityGSH levelsHealth effectsMortalityLand use regression modelsOxidative potentialMedianRegression modelsExposurePM 2.5
2021
The exposome in practice: an exploratory panel study of biomarkers of air pollutant exposure in Chinese people aged 60–69 years (China BAPE Study)
Tang S, Li T, Fang J, Chen R, Cha Y, Wang Y, Zhu M, Zhang Y, Chen Y, Du Y, Yu T, Thompson DC, Godri Pollitt KJ, Vasiliou V, Ji JS, Kan H, Zhang JJ, Shi X. The exposome in practice: an exploratory panel study of biomarkers of air pollutant exposure in Chinese people aged 60–69 years (China BAPE Study). Environment International 2021, 157: 106866. PMID: 34525388, DOI: 10.1016/j.envint.2021.106866.Peer-Reviewed Original ResearchConceptsAir pollutant exposurePotential adverse clinical outcomesPollutant exposureExploratory panel studyAdverse clinical outcomesHealthy elderly subjectsAdverse health outcomesAirborne pollutant exposureAir pollution exposureAdverse health effectsClinical outcomesModifiable factorsElderly subjectsHealthy residentsNovel biomarkersEndogenous exposureExogenous exposureHealth outcomesPotential biomarkersAirborne exposurePollution exposureSuboptimal assessmentAdverse health impactsAssociated biomarkersComprehensive biomarker