2010
Characterization of cytotoxic immune response in skin and mucosal lesions of paracoccidioidomycosis
Pagliari C, Pereira N, Kanashiro L, Stegun F, Croda J, Duarte M, Sotto M. Characterization of cytotoxic immune response in skin and mucosal lesions of paracoccidioidomycosis. Journal Of Cutaneous Pathology 2010, 37: 565-570. PMID: 19702683, DOI: 10.1111/j.1600-0560.2009.01413.x.Peer-Reviewed Original ResearchConceptsNK cellsT cellsMucosal lesionsImmune responseGranzyme BPredominance of CD8Granzyme B expressionNatural killer cellsCytotoxic immune responseNumber of granzymeKiller cellsG3 lesionsCD8G2 lesionsSuch lesionsCompact granulomasLesionsB expressionSame lesionGranulomasMucosaPerforinSkinSuch cellsCells
2009
Leptospirosis pulmonary haemorrhage syndrome is associated with linear deposition of immunoglobulin and complement on the alveolar surface
Croda J, Neto A, Brasil R, Pagliari C, Nicodemo A, Duarte M. Leptospirosis pulmonary haemorrhage syndrome is associated with linear deposition of immunoglobulin and complement on the alveolar surface. Clinical Microbiology And Infection 2009, 16: 593-599. PMID: 19778300, DOI: 10.1111/j.1469-0691.2009.02916.x.Peer-Reviewed Original ResearchConceptsLeptospirosis pulmonary hemorrhage syndromePulmonary hemorrhage syndromeLPHS patientsPulmonary hemorrhageAlveolar surfaceLinear depositionUnique histological patternLife-threatening syndromeImmunoglobulin depositsTreatment regimensPathological featuresPresent studyHistological patternLung specimensLung tissueSevere diseaseAlveolar septaHuman leptospirosisLinear stainingSyndromeZoonotic infectionGranular stainingHemorrhageHeterogeneous stainingPatients