2024
Transmission-reducing and -enhancing monoclonal antibodies against Plasmodium vivax gamete surface protein Pvs48/45
Bansal G, da Silva Araujo M, Cao Y, Shaffer E, Araujo J, Medeiros J, Hayashi C, Vinetz J, Kumar N. Transmission-reducing and -enhancing monoclonal antibodies against Plasmodium vivax gamete surface protein Pvs48/45. Infection And Immunity 2024, 92: e00374-23. PMID: 38289124, PMCID: PMC10929423, DOI: 10.1128/iai.00374-23.Peer-Reviewed Original ResearchDirect membrane feeding assaysTransmission-blocking vaccinesTransmission-blocking vaccine developmentMalaria transmission-blocking vaccineBlocked oocyst developmentInfectivity of gametocytesMale gamete fertilityMonoclonal antibodiesMembrane feeding assaysTransmission-blocking activityPvs48/45Activity of antibodiesNon-overlapping epitopesOocyst developmentPotential vaccine candidatesIndividual MAbsVaccine candidatesEffective immunogensChallenge modelMAbAntibodiesGametocytesEpitopesRecombinant fragmentsEnhanced activity
2016
Evaluation of monoclonal antibodies against pfMSP10 for the prospective use on in vitro growth inhibition assays of peruvian P. falciparum isolates
Villasis E, Bendezu J, Garro K, Nolazco O, Torres K, Infante B, Gamboa D, Vinetz J. Evaluation of monoclonal antibodies against pfMSP10 for the prospective use on in vitro growth inhibition assays of peruvian P. falciparum isolates. International Journal Of Infectious Diseases 2016, 53: 149. DOI: 10.1016/j.ijid.2016.11.365.Peer-Reviewed Original Research