1999
Preliminary Evidence of Low Cortical GABA Levels in Localized 1H-MR Spectra of Alcohol-Dependent and Hepatic Encephalopathy Patients
Behar KL, Rothman DL, Petersen KF, Hooten M, Delaney R, Petroff OA, Shulman GI, Navarro V, Petrakis IL, Charney DS, Krystal JH. Preliminary Evidence of Low Cortical GABA Levels in Localized 1H-MR Spectra of Alcohol-Dependent and Hepatic Encephalopathy Patients. American Journal Of Psychiatry 1999, 156: 952-954. PMID: 10360140, DOI: 10.1176/ajp.156.6.952.Peer-Reviewed Original ResearchConceptsHepatic encephalopathy patientsEncephalopathy patientsGamma-aminobutyric acidHealthy subjectsCortical GABA levelsGABA-ergic systemDetoxified alcohol-dependent patientsAlcohol-dependent patientsNeuroactive amino acidsCerebral cortexGABA levelsOccipital cortexPatientsMetabolite levelsPreliminary evidenceCortexSubjectsLevelsDisease
1998
Dose-Related Ethanol-like Effects of the NMDA Antagonist, Ketamine, in Recently Detoxified Alcoholics
Krystal JH, Petrakis IL, Webb E, Cooney NL, Karper LP, Namanworth S, Stetson P, Trevisan LA, Charney DS. Dose-Related Ethanol-like Effects of the NMDA Antagonist, Ketamine, in Recently Detoxified Alcoholics. JAMA Psychiatry 1998, 55: 354-360. PMID: 9554431, DOI: 10.1001/archpsyc.55.4.354.Peer-Reviewed Original Research
1996
Recurrent self-injurious behavior in forensic patients
Hillbrand M, Young J, Krystal J. Recurrent self-injurious behavior in forensic patients. Psychiatric Quarterly 1996, 67: 33-45. PMID: 8623037, DOI: 10.1007/bf02244273.Peer-Reviewed Original ResearchConceptsSelf-injurious behaviorForensic patientsPsychiatric populationsSelf-injurious patientsGreat therapeutic challengeRecurrent self-injurious behaviorSelf-destructive patientsLonger hospitalizationTherapeutic challengeForensic psychiatric populationHigh prevalencePatientsVigorous interventionDiagnostic measuresPresent studyHospitalizationPopulationPrevalence