2022
Evaluation of the Pfs25-IMX313/Matrix-M malaria transmission-blocking candidate vaccine in endemic settings
Mulamba C, Williams C, Kreppel K, Ouedraogo J, Olotu A. Evaluation of the Pfs25-IMX313/Matrix-M malaria transmission-blocking candidate vaccine in endemic settings. Malaria Journal 2022, 21: 159. PMID: 35655174, PMCID: PMC9161629, DOI: 10.1186/s12936-022-04173-y.Peer-Reviewed Original ResearchConceptsEndemic settingsMalaria transmission-blocking vaccineHuman vaccine trialsTransmission-blocking vaccinesPublic health importanceMosquito vectorsMiddle-income settingsAnti-malarial drugsImmunological mechanismsCandidate vaccinesVaccine trialsHealthy individualsIncome settingsTransmission blockingHealth importanceMalaria controlMalaria parasitesVaccineLocal interventionsDrugsInterventionSettingSexual stagesPfs25Disease
2020
High Plasmodium infection intensity in naturally infected malaria vectors in Africa
Bompard A, Da D, Yerbanga S, Morlais I, Awono-Ambéné P, Dabiré R, Ouédraogo J, Lefèvre T, Churcher T, Cohuet A. High Plasmodium infection intensity in naturally infected malaria vectors in Africa. International Journal For Parasitology 2020, 50: 985-996. PMID: 32681932, DOI: 10.1016/j.ijpara.2020.05.012.Peer-Reviewed Original ResearchConceptsOocyst-positive mosquitoesInfectious blood mealEfficacy of transmissionControl of malariaWild malaria vectorsMalaria parasite transmissionCross-sectional surveyInfection loadSalivary gland sporozoitesMalaria vectorsMalaria endemicityNumber of oocystsInfected mosquitoesMalaria transmissionOocyst prevalenceStrong positive associationPrevalencePositive associationBlood mealOocyst loadInfection intensityEpidemiologyEfficacyParasite transmissionIntervention