2009
Specific Relation Between Abdominal Obesity and Early-Phase Hyperglycemia Is Modulated by Hepatic Insulin Resistance in Healthy Older Women
DiPietro L, Dziura J, Yeckel CW. Specific Relation Between Abdominal Obesity and Early-Phase Hyperglycemia Is Modulated by Hepatic Insulin Resistance in Healthy Older Women. Diabetes Care 2009, 33: 165-167. PMID: 19808930, PMCID: PMC2797964, DOI: 10.2337/dc09-1365.Peer-Reviewed Original ResearchConceptsHepatic insulin resistanceOral glucose tolerance testAbdominal obesityGlucose tolerance testHealthy older womenInsulin resistanceOlder womenTolerance testLow-dose insulin infusionHepatic glucose productionGlucose excursionsInsulin infusionPlasma glucoseAbdominal circumferenceInsulin concentrationsInsulin suppressionMin postchallengeObesityGlycemic responseClamp techniqueGlucose productionWomenHyperglycemiaProduction suppressionPostchallenge
2004
Experience with the continuous glucose monitoring system in a medical intensive care unit.
Goldberg PA, Siegel MD, Russell RR, Sherwin RS, Halickman JI, Cooper DA, Dziura JD, Inzucchi SE. Experience with the continuous glucose monitoring system in a medical intensive care unit. Diabetes Technology & Therapeutics 2004, 6: 339-47. PMID: 15198837, DOI: 10.1089/152091504774198034.Peer-Reviewed Original ResearchConceptsIntensive care unitMedical intensive care unitIll patientsContinuous glucose monitoring systemMedical ICUGlucose monitoring systemGlycemic excursionsCare unitStrict glycemic controlRole of hyperglycemiaBlood glucose levelsMICU patientsDiabetes mellitusGlycemic controlICU patientsClinical outcomesNursing workloadInpatient settingGlucose levelsPatientsStudy subjectsLarger studyBG readingsSES differencesFrequent monitoring
2002
Brain glucose levels are elevated in chronically hyperglycemic diabetic rats: No evidence for protective adaptation by the blood brain barrier
Jacob RJ, Fan X, Evans ML, Dziura J, Sherwin RS. Brain glucose levels are elevated in chronically hyperglycemic diabetic rats: No evidence for protective adaptation by the blood brain barrier. Metabolism 2002, 51: 1522-1524. PMID: 12489061, DOI: 10.1053/meta.2002.36347.Peer-Reviewed Original ResearchConceptsDiabetic ratsBB/Wor diabetic ratsLong-term adverse effectsHyperglycemic diabetic ratsProtective adaptationBlood-brain barrier transferPlasma glucose ratioBlood-brain barrierBeta-hydroxybutyrate levelsBrain glucose levelsECF glucoseAcute hyperglycemiaChronic hyperglycemiaBlood glucoseBrain barrierHyperglycemic groupPeripheral tissuesGlucose levelsBeta-OHBInferior colliculusECF levelsProlonged elevationHyperglycemiaFluid glucoseBrain tissue