2012
Effects on post-prandial glucose and AGE precursors from two initial insulin strategies in patients with Type 2 diabetes uncontrolled by oral agents
Sakharova OV, Lleva RR, Dziura JD, Spollett GR, Howell SK, Beisswenger PJ, Inzucchi SE. Effects on post-prandial glucose and AGE precursors from two initial insulin strategies in patients with Type 2 diabetes uncontrolled by oral agents. Journal Of Diabetes And Its Complications 2012, 26: 333-338. PMID: 22541894, DOI: 10.1016/j.jdiacomp.2012.03.027.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, OralAgedBlood GlucoseBody WeightCross-Over StudiesDiabetes Mellitus, Type 2FastingFemaleGlycated HemoglobinGlycation End Products, AdvancedHumansHypoglycemic AgentsInsulin GlargineInsulin LisproInsulin, Long-ActingMaleMiddle AgedPostprandial PeriodTreatment FailureTreatment OutcomeConceptsOral anti-hyperglycemic drugsPost-prandial glucoseInsulin strategiesFree fatty acidsType 2Post-prandial glucose metabolismProgressive β-cell dysfunctionType 2 diabetes patientsPost-prandial glucose levelsDaily insulin glargineInitial insulin regimenPrecursor of AGEsSingle-center studyClinical Research CenterLong-term diabetic complicationsAnti-hyperglycemic drugsType 2 diabetesΒ-cell dysfunctionCross-over designInitial insulinInsulin regimenOral agentsInsulin regimensInsulin therapyOAD therapy
2008
Abdominal Obesity in Older Women: Potential Role for Disrupted Fatty Acid Reesterification in Insulin Resistance
Yeckel CW, Dziura J, DiPietro L. Abdominal Obesity in Older Women: Potential Role for Disrupted Fatty Acid Reesterification in Insulin Resistance. The Journal Of Clinical Endocrinology & Metabolism 2008, 93: 1285-1291. PMID: 18198225, PMCID: PMC2291490, DOI: 10.1210/jc.2007-1875.Peer-Reviewed Original ResearchConceptsFatty acid reesterificationPeripheral insulin resistanceAbdominal obesityInsulin resistanceHepatic glucose productionAbdominal adiposityOlder womenGlucose utilizationGeneral Clinical Research CenterBasal hepatic glucose productionGlucose productionFree fatty acid metabolismExcess abdominal adiposityPerturbed glucose metabolismGlucose-lowering medicationsHormone replacement therapyClinical Research CenterPeripheral glucose utilizationGlycerol appearance rateInactive older womenTotal body fatCross-sectional studyAbdominal circumference valuesInsulin-stimulated suppressionFree fatty acid ratio
2006
A Randomized Controlled Study of Effects of Dietary Magnesium Oxide Supplementation on Bone Mineral Content in Healthy Girls
Carpenter TO, DeLucia MC, Zhang JH, Bejnerowicz G, Tartamella L, Dziura J, Petersen KF, Befroy D, Cohen D. A Randomized Controlled Study of Effects of Dietary Magnesium Oxide Supplementation on Bone Mineral Content in Healthy Girls. The Journal Of Clinical Endocrinology & Metabolism 2006, 91: 4866-4872. PMID: 17018656, PMCID: PMC2995550, DOI: 10.1210/jc.2006-1391.Peer-Reviewed Original ResearchConceptsBone mineral contentHip bone mineral contentDietary Mg intakeMg supplementationBone massMg intakeSpinal bone mineral contentMid-late pubertyOld Caucasian girlDouble-blind trialClinical Research CenterPrimary outcome measureBone mineral densityCommunity pediatricians' officesSerum mineral levelsMagnesium oxide supplementationPill countDietary diariesTotal hipFemoral neckInterventional studyMineral densityHealthy girlsBone markersOutcome measures