2020
Statistical Methods in Genome-Wide Association Studies
Sun N, Zhao H. Statistical Methods in Genome-Wide Association Studies. Annual Review Of Biomedical Data Science 2020, 3: 1-24. DOI: 10.1146/annurev-biodatasci-030320-041026.Peer-Reviewed Original ResearchGenome-wide association studiesAssociation studiesTraits of interestGenetic architectureIdentification of variantsGWAS dataStatistical methodologyStatistical challengesGenetic risk prediction modelsGenetic markersStatistical methodsHuman diseasesPhenotype informationGenetic variantsTraitsGenotype informationScientific goalsRecent progressGenesVariantsTens of thousandsHundreds of thousandsPrediction modelPathwayThousands
2019
Improving Genetic Association Analysis through Integration of Functional Annotations of the Human Genome
Lu Q, Zhao H. Improving Genetic Association Analysis through Integration of Functional Annotations of the Human Genome. 2019, 679-30. DOI: 10.1002/9781119487845.ch24.Peer-Reviewed Original ResearchGenome-wide association studiesFunctional annotationHuman genomeAssociation analysisAnnotation dataFunctional annotation dataPost-GWAS analysisSummary association statisticsGenetic association analysisGWAS findingsGWAS dataIntegrative analysisAssociation studiesComplex diseasesAssociation statisticsGenetic associationGenomeComputational methodsAnnotationTraitsDirect applicationStatistical powerMost diseasesInterpretable metricsTens of thousands