2024
Using clinical and genetic risk factors for risk prediction of 8 cancers in the UK Biobank
Hu J, Ye Y, Zhou G, Zhao H. Using clinical and genetic risk factors for risk prediction of 8 cancers in the UK Biobank. JNCI Cancer Spectrum 2024, 8: pkae008. PMID: 38366150, PMCID: PMC10919929, DOI: 10.1093/jncics/pkae008.Peer-Reviewed Original ResearchPolygenic risk scoresUK BiobankCancer riskClinical risk factorsRisk of breast cancerRisk factorsPolygenic risk score modelHigh risk of developing cancerRisk of developing cancerLate-onset patientsRisk predictionClinical variablesHigh-risk individualsCox proportional hazards modelsProportional hazards modelGenetic risk factorsBaseline traitsClinical risk modelRisk scoreEarly-onset patientsHazards modelLate-onset groupEarly-onset groupBreast cancerHigh risk
2023
Predicting Breast Cancer Risk for Women Veterans of African Ancestry in the Million Veteran Program
Luoh S, Minnier J, Zhao H, Gao L. Predicting Breast Cancer Risk for Women Veterans of African Ancestry in the Million Veteran Program. Health Equity 2023, 7: 303-306. PMID: 37284538, PMCID: PMC10240329, DOI: 10.1089/heq.2023.0011.Peer-Reviewed Original ResearchBreast cancer riskBreast cancerMillion Veteran ProgramCancer riskPolygenic risk scoresWomen veteransHigher breast cancer riskRisk prediction instrumentsIncident breast cancerLow-risk womenBreast cancer preventionBreast cancer incidenceIndividual breast cancer riskBreast cancer mortalityPredicting Breast Cancer RiskBreast cancer screeningVeteran ProgramMajor health threatPrediction instrumentGenetic variantsEuropean ancestry womenProspective cohortRisk womenCancer mortalityCancer screening